Abstract:
BACKGROUND:Chocolate consumption has been inconsistently associated with risk of atrial fibrillation (AF). We investigated the association between chocolate consumption and risk of AF in Swedish adults from two cohort studies and conducted a meta-analysis to summarize available evidence from cohort studies on this topic. METHODS:Our study population comprised 40,009 men from the Cohort of Swedish Men and 32,486 women from the Swedish Mammography Cohort. Incident AF cases were ascertained through linkage with the Swedish National Patient Register. Published cohort studies of chocolate consumption in relation to risk of AF were identified by a PubMed search through September 14, 2017. RESULTS:During a mean follow-up of 14.6 years, AF was diagnosed in 9978 Swedish men and women. Compared with non-consumers, the multivariable hazard ratio of AF for those in the highest category of chocolate consumption (≥3-4 servings/week) was 0.96 (95% CI 0.88-1.04). In a random-effects meta-analysis of 5 cohort studies, including 180,454 participants and 16,356 AF cases, the hazard ratios of AF were 0.97 (95% CI 0.94-1.01) per 2 servings/week increase in chocolate consumption and 0.96 (95% CI 0.90-1.03) for the highest versus lowest category of chocolate consumption. CONCLUSION:Available data provide no evidence of an association of chocolate consumption with risk of AF.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Larsson SC,Drca N,Jensen-Urstad M,Wolk Adoi
10.1016/j.ahj.2017.09.013subject
Has Abstractpub_date
2018-01-01 00:00:00pages
86-90eissn
0002-8703issn
1097-6744pii
S0002-8703(17)30287-9journal_volume
195pub_type
杂志文章,meta分析,评审abstract::Between 1982 and 1988, we observed 312 patients who were affected by syncope or presyncope and whose spontaneous symptoms could be reproduced by means of carotid sinus massage (CSH); no other definite cause of syncope could be identified. The clinical outcome during a 2- to 8-year follow-up period (mean 44 +/- 24 mont...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(92)90507-r
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND:The aim of this study was to describe the effect of intravenous metoprolol on the intensity of chest pain before hospital admission in patients with suspected acute myocardial infarction AMI). METHODS AND RESULTS:Two hundred sixty-two patients with acute chest pain and suspected AMI were randomly assigned b...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-8703(99)70405-9
更新日期:1999-05-01 00:00:00
abstract::A 47-year-old man presented with exertional angina. Selective coronary arteriography showed complete systolic segmental occlusion of the left anterior descending coronary artery producing milking effect. Permanent relief of symptoms was achieved by surgical excision of myocardial bridges. Postoperative angiography per...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(80)90118-0
更新日期:1980-08-01 00:00:00
abstract:BACKGROUND:Although recent data support an early invasive management in acute coronary syndromes (ACS), overall evidence appears conflicting. We performed a metaregression to explore the impact of intracoronary stenting and aggressive antiplatelet treatment on the risk/benefit ratio of an early invasive approach. METH...
journal_title:American heart journal
pub_type: 杂志文章,评审
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journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
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更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:There is growing interest in assessing therapy for acute myocardial infarction. Because thrombolysis was not a study therapy in the GISSI-3 trial, the decision about thrombolysis was left to the responsible physicians. We evaluated the data on thrombolytic therapy among patients with acute myocardial infarct...
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pub_type: 杂志文章
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更新日期:1998-03-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,多中心研究
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更新日期:2000-02-01 00:00:00
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journal_title:American heart journal
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更新日期:1994-05-01 00:00:00
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更新日期:2000-08-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(05)80010-9
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(95)90390-9
更新日期:1995-06-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90283-n
更新日期:1991-12-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(98)70351-5
更新日期:1998-01-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(94)90505-3
更新日期:1994-01-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(75)90080-0
更新日期:1975-03-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(97)70226-6
更新日期:1997-03-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2010-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2005-06-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2007-11-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2008-02-01 00:00:00
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:1996-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2000-07-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(05)80050-x
更新日期:1990-03-01 00:00:00
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journal_title:American heart journal
pub_type: 社论
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更新日期:1991-02-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
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更新日期:1994-03-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2010.05.024
更新日期:2010-08-01 00:00:00