Abstract：
OBJECTIVE:To assess the monetary savings resulting from a pharmacist intervention on the appropriateness of prescribed drugs in community-dwelling polymedicated (≥8 drugs) elderly people (≥70 years). METHOD:An evaluation of pharmaceutical expenditure reduction was performed within a randomised, multicentre clinical trial. The study intervention consisted of a pharmacist evaluation of all drugs prescribed to each patient using the "Good Palliative-Geriatric Practice" algorithm and the "Screening Tool of Older Persons Prescriptions/Screening Tool to Alert doctors to Right Treatment" criteria (STOPP/START). The control group followed the routine standard of care. A time horizon of one year was considered and cost elements included human resources and drug expenditure. RESULTS:490 patients (245 in each group) were analysed. Both groups experienced a decrease in drug expenditure 12 months after the study started, but this decrease was significantly higher in the intervention group than in the control group (-14.3% vs.-7.7%; p=0.041). Total annual drug expenditure decreased 233.75 €/patient (95% confidence interval [95%CI]: 169.83-297.67) in the intervention group and 169.40 €/patient (95%CI: 103.37-235.43) in the control group over a one-year period, indicating that 64.30 € would be the drug expenditure savings per patient a year attributable to the study intervention. The estimated return per Euro invested in the programme would be 2.38 € per patient a year on average. CONCLUSIONS:The study intervention is a cost-effective alternative to standard care that could generate a positive return of investment.
journal_name
Gac Sanitjournal_title
Gaceta sanitariaauthors
Campins L,Serra-Prat M,Palomera E,Bolibar I,Martínez MÀ,Gallo Pdoi
10.1016/j.gaceta.2017.09.002subject
Has Abstractpub_date
2019-01-01 00:00:00pages
106-111issue
2eissn
0213-9111issn
1578-1283pii
S0213-9111(17)30220-0journal_volume
33pub_type
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