Of Mice and Man: Differential DNMT Dependence in Mammalian ESCs.

Abstract:

:Liao et al. (2015) recently reported on the effects of disrupting DNA methyltransferase activity in human embryonic stem cells (hESCs). This work highlights key differences between mammalian ESC models upon the loss of these essential proteins and provides comprehensive base resolution methylome maps of DNMT targets during human development.

journal_name

Cell Stem Cell

journal_title

Cell stem cell

authors

Bogdanović O,Lister R

doi

10.1016/j.stem.2015.04.009

subject

Has Abstract

pub_date

2015-05-07 00:00:00

pages

459-60

issue

5

eissn

1934-5909

issn

1875-9777

pii

S1934-5909(15)00167-8

journal_volume

16

pub_type

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