Investigation of an outbreak of varicella in Chandigarh, North India, using a real-time polymerase chain reaction approach.

Abstract:

:Outbreaks of varicella are reported when susceptible population accumulates. This study reports a chickenpox outbreak in Burail in August 2014, wherein 20 laboratory-confirmed cases were identified by the detection of varicella zoster virus (VZV) DNA and VZV IgM antibodies. The viral load between vesicular swabs and serum samples from 8 patients with active lesions was found to have good correlation and further also related with disease severity. Real-time polymerase chain reaction can be useful for early diagnosis of an outbreak and vesicular swab can be used as a less invasive sample for assessing the disease severity.

journal_name

Indian J Med Microbiol

authors

Singh MP,Kaur R,Kumar A,Gupta M,Garg S,Ratho RK

doi

10.4103/ijmm.IJMM_16_420

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

417-420

issue

3

eissn

0255-0857

issn

1998-3646

pii

IndianJMedMicrobiol_2017_35_3_417_216620

journal_volume

35

pub_type

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