Oxygen Sensitivity of Placental Trophoblast Connexins 43 and 46: A Role in Preeclampsia?

abstract：:Vascularization is essential for bone development, fracture healing, and bone tissue engineering. We have previously described that coculture of primary human osteoblasts (hOBs) and human umbilical vein endothelial cells (HUVECs) improves differentiation of both cell types. Investigating the role of microRNAs (miRNAs)...

journal_title：Journal of cellular biochemistry

authors： Strassburg S,Nabar N,Lampert F,Goerke SM,Pfeifer D,Finkenzeller G,Stark GB,Simunovic F

更新日期：2017-07-01 00:00:00

abstract：:The microenvironment of the cancer cell is pivotal to its phenotypic regulation. One of the central components of the microenvironment is temperature. An elevation in environmental temperature has been shown to increase the cancer cell's susceptibility to chemo- and radiation therapy. The goal of the studies described...

journal_title：Journal of cellular biochemistry

authors： Zeng Y,Kulkarni P,Inoue T,Getzenberg RH

更新日期：2009-05-01 00:00:00

abstract：:Extracellular nucleotides and nucleosides have emerged as important elements regulating tissue homeostasis. Acting through specific receptors, have the ability to control gene expression patterns to direct cellular fate. We observed that SKOV-3 cells express the ectonucleotidases: ectonucleotide pyrophosphatase 1 (ENP...

journal_title：Journal of cellular biochemistry

authors： Martínez-Ramírez AS,Díaz-Muñoz M,Battastini AM,Campos-Contreras A,Olvera A,Bergamin L,Glaser T,Jacintho Moritz CE,Ulrich H,Vázquez-Cuevas FG

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:It has been reported that the fastigial nucleus (FSN) plays an important role in the development of vascular dementia (VD). Both autophagy and inflammation are functionally involved in the pathogenesis of VD. In this study, we aimed to evaluate the therapeutic effect of electrical cerebellar fastigial nucleu...

journal_title：Journal of cellular biochemistry

authors： Xia D,Sui R,Min L,Zhang L,Zhang Z

更新日期：2019-04-01 00:00:00

abstract：:Ultraprofound hypothermia (< 5 degrees C) induces changes to cell membranes such as liquid-to-gel lipid transitions and oxidative stress that have a negative effect on membrane function and cell survival. We hypothesized that fatty acid substitution of endothelial cell lipids and alterations in their unsaturation woul...

journal_title：Journal of cellular biochemistry

authors： Zieger MA,Gupta MP,Siddiqui RA

更新日期：2006-10-15 00:00:00

abstract：:Using computer stress-induced duplex destabilization (SIDD) analysis and binding experiments, we identified a S/MAR element (-599/-200 bp) (Hp-S/MAR) adjacent to the cis-element (-165/-56 bp) in the rat haptoglobin gene. We examined its functional interactions with the lamins and lamin-associated proteins in the basal...

journal_title：Journal of cellular biochemistry

authors： Vidaković M,Dinić S,Grdović N,Mihailović M,Uskoković A,Quesada P,Poznanović G

更新日期：2009-08-15 00:00:00

abstract：:The human myeloid nuclear differentiation antigen (MNDA) is expressed specifically in maturing cells of the myelomonocytic lineage and in monocytes and granulocytes. Epitope enhancement was used to confirm the strict lineage- and stage-specific expression of MNDA in bone marrow as well as in other paraffin-embedded fi...

journal_title：Journal of cellular biochemistry

authors： Kao WY,Briggs JA,Kinney MC,Jensen RA,Briggs RC

更新日期：1997-05-01 00:00:00

abstract：:The mitogen regulated protein/proliferin (MRP/PLF) gene is transcribed in primary mouse embryo fibroblasts (MEFs), but the pre-mRNA is not properly converted into a stable cytoplasmic mRNA and instead is rapidly degraded, apparently in the nucleus [Malyankar et al. (1994): Proc Natl Acad Sci USA 91:335-359]. In 3T3 ce...

journal_title：Journal of cellular biochemistry

authors： Malyankar UM,Rittling SR,Denhardt DT

更新日期：1996-02-01 00:00:00

abstract：:The promoter of the mouse thymidylate synthase (TS) gene lacks a TATAA box and an initiator element, is bidirectional and initiates transcription at multiple start sites across broad initiation windows upstream and downstream of the 30 nt essential promoter region. The TS promoter also plays an essential role in the p...

journal_title：Journal of cellular biochemistry

authors： Kapadia F,Johnson LF

更新日期：2006-02-15 00:00:00

abstract：OBJECTIVE:Long intergenic noncoding RNA-p21 (lincRNA-p21) has been proved in the pathogenesis of aortic aneurysms, while its functionality in thoracic aortic aneurysms (TAA) and the mechanism of function remains unclear. Therefore our study aimed to investigate the role of lincRNA-p21 in TAA. METHODS:Aortic media spec...

journal_title：Journal of cellular biochemistry

authors： Hu W,Wang Z,Li Q,Wang J,Li L,Jiang G

更新日期：2019-03-01 00:00:00

abstract：:The proteins of 14-3-3 family are substantially involved in the regulation of many biological processes including the apoptosis. We studied the changes in the expression of five 14-3-3 isoforms (beta, gamma, epsilon, tau, and zeta) during the apoptosis of JURL-MK1 and K562 cells. The expression level of all these prot...

journal_title：Journal of cellular biochemistry

authors： Kuzelová K,Grebenová D,Pluskalová M,Kavan D,Halada P,Hrkal Z

更新日期：2009-03-01 00:00:00

abstract：:c-fos gene has a close relationship with the osteoblasts. Mechanical signal effect on osteoblasts would change the expression level of c-fos. Authors introduce the signal pathways of four cis-response elements on the promoter of c-fos, that is, CRE (cAMP responsive element), FAP-1 (Fbs-AP-1 site), SRE (serum response ...

journal_title：Journal of cellular biochemistry

authors： He H,Ping F

更新日期：2009-04-01 00:00:00

abstract：:Recent data suggest that megakaryocytes (MKs) play a role in skeletal homeostasis. In vitro and in vivo data show that MKs stimulate osteoblast (OB) proliferation and inhibit osteoclast (OC) formation, thus favoring net bone deposition. There are several mouse models with dysregulated megakaryopoiesis and resultant hi...

journal_title：Journal of cellular biochemistry

authors： Ciovacco WA,Cheng YH,Horowitz MC,Kacena MA

更新日期：2010-03-01 00:00:00

abstract：:In this report, we describe a human immunodeficiency virus type-1 (HIV-1)-infected promyelocytic cell line, OM, derived from HL-60 cells. Although the OM cell line was biologically cloned twice, the pattern of HIV-1 expression during culture appeared analogous to a classical acute spreading infection and was inhibited...

journal_title：Journal of cellular biochemistry

authors： Butera ST,Perez VL,Besansky NJ,Chan WC,Wu BY,Nabel GJ,Folks TM

更新日期：1991-04-01 00:00:00

abstract：:We examined the mRNA expression of scleraxis, a non-myogenic helix-loop-helix type transcription factor in C2C12 myogenic cells. Scleraxis mRNA has been shown to be expressed in sclerotome and perichondrium of the embryos. We found that C2C12 cells express 1.2 kb scleraxis mRNA constitutively. Since BMP was reported t...

journal_title：Journal of cellular biochemistry

authors： Liu Y,Nifuji A,Tamura M,Wozney JM,Olson EN,Noda M

更新日期：1997-10-01 00:00:00

abstract：:The growth of capillary endothelial cells (BCE) is an important regulatory step in the formation of capillary blood vessels. In vivo, the proliferation of these cells is stringently controlled. In vitro they can be stimulated by polypeptide growth factors, such as acidic fibroblast growth factor (aFGF) and basic fibro...

journal_title：Journal of cellular biochemistry

authors： Weich HA,Iberg N,Klagsbrun M,Folkman J

更新日期：1991-10-01 00:00:00

abstract：:Lysozyme (LYZ) c-like proteins are primarily present in the testis and epididymis of male reproductive tissues. Here, we report a novel member of the c-type LYZ family, the seminal vesicle-secreted LYZ c-like protein (SVLLP). Three forms of SVLLP were purified from mouse seminal vesicle secretions and characterized as...

journal_title：Journal of cellular biochemistry

authors： Ou CM,Lee RK,Lin MH,Lu CH,Yang TH,Yeh LY,Tsai PJ,Li SH

更新日期：2021-01-19 00:00:00

abstract：:Excitatory amino acids (EAAs) are found present in the nervous and reproductive systems of animals. Numerous studies have demonstrated a regulatory role for Glutamate (Glu), d-aspartate ( d-Asp) and N-methyl- d-aspartate (NMDA) in the control of spermatogenesis. EAAs are able to stimulate the Glutamate receptors, incl...

journal_title：Journal of cellular biochemistry

authors： Santillo A,Falvo S,Di Fiore MM,Di Giacomo Russo F,Chieffi P,Usiello A,Pinelli C,Baccari GC

更新日期：2019-02-14 00:00:00

abstract：:The physiologically active form of vitamin D3, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) has influence over osteoclastogenesis and myelopoiesis, but the regulational mechanism is not well-defined. In this report, formation of osteoclast-like (OCL) cells from primitive myeloid colony-forming cells (PM-CFC) as mediated by ...

journal_title：Journal of cellular biochemistry

authors： Qi DY,Perkins SL,Kling SJ,Russell RG

更新日期：1999-03-01 00:00:00

abstract：:Serological proteins of neuroblastoma were profiled and analyzed by ProteinChip-SELDI-TOF MS technology with five types of protein chips. By comparing with normal control, a number of protein or polypeptide signals were found significantly and consistently different in their intensities (expression levels) in tumor se...

journal_title：Journal of cellular biochemistry

authors： He QY,Zhu R,Ren Y,Tam PK,Chiu JF

更新日期：2005-05-01 00:00:00

abstract：:Induced pluripotent stem cells (iPSC) hold tremendous potential for personalized cell-based repair strategies to treat musculoskeletal disorders. To establish human iPSCs as a potential source of viable chondroprogenitors for articular cartilage repair, we assessed the in vitro chondrogenic potential of the pluripoten...

journal_title：Journal of cellular biochemistry

authors： Guzzo RM,Gibson J,Xu RH,Lee FY,Drissi H

更新日期：2013-02-01 00:00:00

abstract：:Receptor activator of NF-kappaB ligand (RANKL) is a critical osteoclastogenic factor that is expressed on bone marrow stromal/preosteoblast cells. Most bone resorption stimuli induce osteoclast formation by modulating RANKL expression in these cells. However, little is known about the mechanisms regulating RANKL gene ...

journal_title：Journal of cellular biochemistry

authors： Sundaram K,Mani SK,Kitatani K,Wu K,Pestell RG,Reddy SV

更新日期：2008-04-15 00:00:00

abstract：:The PML protein and PML nuclear bodies (PML-NB) are implicated in multiple cellular functions relevant to tumor suppression, including DNA damage response. In most cases of acute promyelocytic leukemia, the PML and retinoic acid receptor alpha (RARA) genes are translocated, resulting in expression of oncogenic PML-RAR...

journal_title：Journal of cellular biochemistry

authors： Yeung PL,Denissova NG,Nasello C,Hakhverdyan Z,Chen JD,Brenneman MA

更新日期：2012-05-01 00:00:00

abstract：:Perilipin and ADRP, located on the surface of intracellular lipid droplets, are proposed to be involved in adipocyte lipid metabolism. The aim of the present study was to investigate the effect of PKA and PKC activities on the distribution of perilipin and ADRP in primary cultured adrenal cells, and the role of ERK in...

journal_title：Journal of cellular biochemistry

authors： Fong TH,Yang CC,Greenberg AS,Wang SM

更新日期：2002-01-01 00:00:00

abstract：:The emergence of multi-drug resistant strains and co-occurrence of tuberculosis with HIV creates a major burden to the human health globally. Failure of primary antibacterial therapy necessitates the identification of new mycobacterial drugs. In this study, a comprehensive analysis involving bottom-up systems biology ...

journal_title：Journal of cellular biochemistry

authors： Khan S,Somvanshi P,Bhardwaj T,Mandal RK,Dar SA,Wahid M,Jawed A,Lohani M,Khan M,Areeshi MY,Haque S

更新日期：2018-03-01 00:00:00

abstract：:Angiotensin converting enzyme (ACE) 2 is a carboxypeptidase that shares 42% amino acid homology with ACE. Little is known about the regulation or pattern of expression of ACE2 in the mouse lung, including its definitive cellular distribution or developmental changes. Based on Northern blot and RT-PCR data, we report t...

journal_title：Journal of cellular biochemistry

authors： Wiener RS,Cao YX,Hinds A,Ramirez MI,Williams MC

更新日期：2007-08-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) is an incidence rate nearly equal to its mortality rate. The poor prognosis of the disease can be explained by the absence of effective biomarkers for screening and early detection, together with the aggressive behavior and resistance to the currently available chemotherapy. The...

journal_title：Journal of cellular biochemistry

authors： Barati Bagherabad M,Afzaljavan F,ShahidSales S,Hassanian SM,Avan A

更新日期：2019-03-01 00:00:00

abstract：:The NAD-dependent deacetylase Sirtuin 1 (SIRT1) plays a vital role in leukemogenesis. Nicotinamide (NAM) is the principal NAD+ precursor and a noncompetitive inhibitor of SIRT1. In our study, we showed that NAM enhanced the sensitivity of chronic myeloid leukemia (CML) to doxorubicin (DOX) via SIRT1. We found that SIR...

journal_title：Journal of cellular biochemistry

authors： Pan S,Leng J,Deng X,Ruan H,Zhou L,Jamal M,Xiao R,Xiong J,Yin Q,Wu Y,Wang M,Yuan W,Shao L,Zhang Q

更新日期：2020-01-01 00:00:00

abstract：:The Epstein-Barr virus (EBV) SM protein is a member of a highly conserved family of proteins present in most mammalian herpes viruses. There is a significant amount of functional and sequence divergence among the homologs encoded by the human herpes viruses, including differences in mechanism of action and varying eff...

journal_title：Journal of cellular biochemistry

authors： Swaminathan S

更新日期：2005-07-01 00:00:00

abstract：:Multidrug-resistance due to "β lactamases having the expanded spectrum" (ESBLs) in members of Enterobacteriaceae is a matter of continued clinical concern. CTX-M is among the most common ESBLs in Enterobacteriaceae family. In the present study, a nanoformulation of cefotaxime was prepared using gold nanoparticles to c...

journal_title：Journal of cellular biochemistry

authors： Shaikh S,Rizvi SMD,Shakil S,Hussain T,Alshammari TM,Ahmad W,Tabrez S,Al-Qahtani MH,Abuzenadah AM

更新日期：2017-09-01 00:00:00