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Increased efficacy and toxicity of lidocaine in patients on beta-blockers.

Abstract：

:The greatest differences in ventricular arrhythmias and adverse effects of lidocaine observed in this study were between patients on both lidocaine and a beta-adrenoceptor blocking agent and those on neither drug. Although free fractions of lidocaine and methylglycylxylidine tended to be higher in patients on beta-adrenoceptor blocking agents, this difference was not significant nor were any other differences in serum drug levels observed.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Wyse DG,Kellen J,Tam Y,Rademaker AW

doi

10.1016/0167-5273(88)90009-5

subject

Has Abstract

pub_date

1988-10-01 00:00:00

pages

59-70

issue

1

eissn

0167-5273

issn

1874-1754

pii

0167-5273(88)90009-5

journal_volume

21

pub_type

临床试验,杂志文章

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