Fbxl11 Is a Novel Negative Element of the Mammalian Circadian Clock.

abstract：:Among the scientific resources that Colin Pittendrigh passed on to his colleagues after his death in 1996 were two unpublished papers. These manuscripts, developed first in the mid-1960s and continually updated and refined through the late 1970s, centered on the development and experimental exploration of a model of c...

journal_title：Journal of biological rhythms

authors： Tackenberg MC,Johnson CH,Page TL,Daan S

更新日期：2017-08-01 00:00:00

abstract：:Honey bee workers care for ("nurse") the brood around the clock without circadian rhythmicity, but then they forage outside with strong circadian rhythms and a consolidated nightly rest. This chronobiological plasticity is associated with variation in the expression of the canonical "clock genes" that regulate the cir...

journal_title：Journal of biological rhythms

authors： Rodriguez-Zas SL,Southey BR,Shemesh Y,Rubin EB,Cohen M,Robinson GE,Bloch G

更新日期：2012-02-01 00:00:00

abstract：:The SCN has long had organizational schemas imposed on it. In most, the SCN is dichotomized, with one region typically associated with the presence of vasopressin cells and the other associated with cells containing vasoactive intestinal polypeptide and certain afferent terminal fields. If assumed to be accurate, the ...

journal_title：Journal of biological rhythms

authors： Morin LP

更新日期：2007-02-01 00:00:00

abstract：:Previous research has demonstrated a clear link between late chronotype and depression. The vulnerability factors underpinning this link, however, are unclear. Here the relationship between two specific emotion regulation strategies, cognitive reappraisal and expressive suppression, and chronotype was investigated usi...

journal_title：Journal of biological rhythms

authors： Watts AL,Norbury R

更新日期：2017-08-01 00:00:00

abstract：:The circadian rhythm of eclosion activity and its pacemaker were analyzed in a series of latitudinal races of Drosophila auraria ranging from 34.2 degrees to 42.9 degrees N in Japan. The phase of the rhythm (psi EL) to the daily photoperiod (PP) changes as daylength is increased, and the slope of psi EL (PP) changes w...

journal_title：Journal of biological rhythms

authors： Pittendrigh CS,Takamura T

更新日期：1989-07-01 00:00:00

abstract：:Siberian hamsters (Phodopus sungorus) exhibit changes in immune function following adaptation to short photoperiods, including a marked attenuation of energetically expensive thermoregulatory and behavioral responses to gram-negative bacterial infections. Whether this seasonal attenuation of the immune response is idi...

journal_title：Journal of biological rhythms

authors： Baillie SR,Prendergast BJ

更新日期：2008-02-01 00:00:00

abstract：:The synchronizing stimulus, its transduction site, and the afferent pathways responsible for feeding entrainment remain unknown. In fish, the role of the diet in the development of feeding anticipatory activity (FAA) is not well understood and fundamental questions on the mechanisms of feeding entrainment, such as the...

journal_title：Journal of biological rhythms

authors： Sánchez-Vázquez FJ,Aranda A,Madrid JA

更新日期：2001-02-01 00:00:00

abstract：:The authors examined spatial working memory in the Morris water maze during the activity and rest periods of Wistar rats. Wheel-running activity was measured continuously as a marker of circadian phase. To minimize possible masking effects on performance, animals were placed in constant dim light the day before testin...

journal_title：Journal of biological rhythms

authors： Valentinuzzi VS,Menna-Barreto L,Xavier GF

更新日期：2004-08-01 00:00:00

abstract：:An outstanding unresolved issue in chronobiology is how the level of locomotor activity influences length of the free-running, endogenous circadian period (tau). To address this issue, the authors studied a novel model, 4 replicate lines of laboratory house mice (Mus domesticus) that had been selectively bred for high...

journal_title：Journal of biological rhythms

authors： Koteja P,Swallow JG,Carter PA,Garland T Jr

更新日期：2003-12-01 00:00:00

abstract：:Activity patterns are the product of interactions between an internal circadian clock and direct responses to photic and nonphotic features of the environment that are said to "mask" the influence of that clock. Evolutionary transitions between nocturnality and diurnality involve changes in mechanisms underlying both ...

journal_title：Journal of biological rhythms

authors： Cohen R,Smale L,Kronfeld-Schor N

更新日期：2010-02-01 00:00:00

abstract：:Sleep disturbances are an all-too-familiar symptom of jet lag and a prime source of complaints for transmeridian travelers and flight crews alike. They are the result of a temporary loss of synchrony between an abruptly shifted sleep period, timed in accordance with the new local day-night cycle, and a gradually reent...

journal_title：Journal of biological rhythms

authors： Boulos Z,Campbell SS,Lewy AJ,Terman M,Dijk DJ,Eastman CI

更新日期：1995-06-01 00:00:00

abstract：:Subjective well-being largely depends on mood, which shows circadian rhythmicity and can be linked to rhythms in many physiological circadian markers, such as melatonin and cortisol. In healthy young volunteers mood is influenced by an interaction of circadian phase and the duration of time awake. The authors analyzed...

journal_title：Journal of biological rhythms

authors： Birchler-Pedross A,Schröder CM,Münch M,Knoblauch V,Blatter K,Schnitzler-Sack C,Wirz-Justice A,Cajochen C

更新日期：2009-06-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) drives circadian rhythms in locomotion through coupled, single-cell oscillations. Global genetic deletion of the neuropeptide Vip or its receptor Vipr2 results in profound deficits in daily synchrony among SCN cells and daily rhythms in locomotor behavior and glucocorticoid secretion....

journal_title：Journal of biological rhythms

authors： Mazuski C,Chen SP,Herzog ED

更新日期：2020-10-01 00:00:00

abstract：:Casein kinase 1ε (CK1ε) performs key phosphorylation reactions in the circadian clock mechanism that determine period. We show that the central clock protein PERIOD2 (PER2) not only acts as a transcriptional repressor but also inhibits the autoinactivation of CK1ε, thereby promoting CK1ε activity. Moreover, PER2 recip...

journal_title：Journal of biological rhythms

authors： Qin X,Mori T,Zhang Y,Johnson CH

更新日期：2015-06-01 00:00:00

abstract：:Temperature compensation and period determination by casein kinase 1 (CK1) are conserved features of eukaryotic circadian rhythms, whereas the clock gene transcription factors that facilitate daily gene expression rhythms differ between phylogenetic kingdoms. Human red blood cells (RBCs) exhibit temperature-compensate...

journal_title：Journal of biological rhythms

authors： Beale AD,Kruchek E,Kitcatt SJ,Henslee EA,Parry JSW,Braun G,Jabr R,von Schantz M,O'Neill JS,Labeed FH

更新日期：2019-04-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) drives and synchronizes daily rhythms at the cellular level via transcriptional-translational feedback loops comprising clock genes such as Bmal1 and Period (Per). Glycogen synthase kinase 3 (GSK3), a serine/threonine kinase, phosphorylates at least 5 core clock proteins and shows diu...

journal_title：Journal of biological rhythms

authors： Besing RC,Paul JR,Hablitz LM,Rogers CO,Johnson RL,Young ME,Gamble KL

更新日期：2015-04-01 00:00:00

abstract：:We examine theoretical models for circadian oscillations based on transcriptional regulation in Drosophila and Neurospora. For Drosophila, the molecular model is based on the negative feedback exerted on the expression of the per and tim genes by the complex formed between the PER and TIM proteins. For Neurospora, sim...

journal_title：Journal of biological rhythms

authors： Leloup JC,Gonze D,Goldbeter A

更新日期：1999-12-01 00:00:00

abstract：:Abstract The cyanobacterial clock protein KaiC regulates the circadian cycle by exhibiting rhythms in transcription, translation, and phosphorylation. KaiC phosphorylation persists in circadian cycling even under transcription-less conditions and was reconstituted in vitro by incubating KaiC, KaiA, and KaiB. This pres...

journal_title：Journal of biological rhythms

authors： Takigawa-Imamura H,Mochizuki A

更新日期：2006-10-01 00:00:00

abstract：:Transplantation of the fetal suprachiasmatic nucleus (SCN) in arrhythmic SCN-lesioned rats can reinstate circadian drinking rhythms in 40% to 50% of the cases. In the current article, it was investigated whether the failure in the other rats could be due to the absence of a circadian rhythm in the grafted SCN, using a...

journal_title：Journal of biological rhythms

authors： van Esseveldt KE,van der Geest BA,Duindam H,Rietveld WJ,Boer GJ

更新日期：1999-02-01 00:00:00

abstract：:The human circadian timing system has previously been shown to free run with a period slightly longer than 24 h in subjects living in the laboratory under conditions of forced desynchrony. In forced desynchrony, subjects are shielded from bright light and periodic time cues and are required to live on a day length out...

journal_title：Journal of biological rhythms

authors： Kelly TL,Neri DF,Grill JT,Ryman D,Hunt PD,Dijk DJ,Shanahan TL,Czeisler CA

更新日期：1999-06-01 00:00:00

abstract：:Photoreception in the mammalian retina is not restricted to rods and cones but extends to a small number of intrinsically photosensitive retinal ganglion cells expressing the photopigment melanopsin. These mRGCs are especially important contributors to circadian entrainment, the pupil light reflex, and other so-called...

journal_title：Journal of biological rhythms

authors： Enezi Ja,Revell V,Brown T,Wynne J,Schlangen L,Lucas R

更新日期：2011-08-01 00:00:00

abstract：:We investigated the extent to which photoperiodic fluctuations synchronize annual thyroid and gonadal rhythmicity in edible dormice. The effects of different daylength manipulations (LD 4:20, LD 6:18, LD 18:6, LD 20:4) were examined during the two critical ascending and regressive phases of the annual plasma testoster...

journal_title：Journal of biological rhythms

authors： Jallageas M,Mas N,Nouguier-Soulé J

更新日期：1991-01-01 00:00:00

abstract：:Seasonal changes in numerous aspects of mammalian immune function arise as a result of the annual variation in environmental day length (photoperiod), but it is not known if absolute photoperiod or relative change in photoperiod drives these changes. This experiment tested the hypothesis that an individual's history o...

journal_title：Journal of biological rhythms

authors： Prendergast BJ,Pyter LM

更新日期：2009-12-01 00:00:00

abstract：:Honey bee (Apis mellifera) workers emerge from the pupae with no circadian rhythms in behavior or brain clock gene expression but show strong rhythms later in life. This postembryonic development of circadian rhythms is reminiscent of that of infants of humans and other primates but contrasts with most insects, which ...

journal_title：Journal of biological rhythms

authors： Eban-Rothschild A,Shemesh Y,Bloch G

更新日期：2012-06-01 00:00:00

abstract：:The safety and efficacy of chemotherapeutics can vary as a function of the time of their delivery during the day. This study aimed to improve the treatment of glioblastoma (GBM), the most common brain cancer, by testing whether the efficacy of the DNA alkylator temozolomide (TMZ) varies with the time of its administra...

journal_title：Journal of biological rhythms

authors： Slat EA,Sponagel J,Marpegan L,Simon T,Kfoury N,Kim A,Binz A,Herzog ED,Rubin JB

更新日期：2017-04-01 00:00:00

abstract：:Testicular growth was monitored in male ferrets subjected to one of the following photoperiodic treatments begun at weaning (8 weeks of age): 8 hr light/day (short days), 18 hr light/day (long days), or short days followed by transition to long days at either 10, 12, or 14 weeks of age. Mean ages to achieve adult test...

journal_title：Journal of biological rhythms

authors： Sisk CL

更新日期：1990-10-01 00:00:00

abstract：:The authors analyzed the upstream regulatory region of purF, a gene that is expressed in a minority phase that peaks at dawn (class 2 circadian phasing) in Synechococcus elongatus, to determine whether specific cis elements are responsible for this characteristic expression pattern. Fusions of various promoter-bearing...

journal_title：Journal of biological rhythms

authors： Min H,Liu Y,Johnson CH,Golden SS

更新日期：2004-04-01 00:00:00

abstract：:We have recently shown that molecular rhythms in the murine suprachiasmatic nucleus (SCN) are affected by repeated social defeat (SD) during the dark/active phase (social defeat dark [SDD]), while repeated SD during the light/inactive phase (social defeat light [SDL]) had no influence on PERIOD2::LUCIFERASE explant rh...

journal_title：Journal of biological rhythms

authors： Bartlang MS,Oster H,Helfrich-Förster C

更新日期：2015-06-01 00:00:00

abstract：:On the southern Iberian Peninsula, the seasonal life history of the large white butterfly, Pieris brassicae, comprises 2 different photoperiodically induced developmental arrests: a hibernation diapause at photophases < 11 h and an estivation diapause at photophases > 14 h. At intermediate photophases (12 h to 13 h), ...

journal_title：Journal of biological rhythms

authors： Spieth HR,Xue F,Strau K

更新日期：2004-12-01 00:00:00

abstract：:The mammalian endogenous circadian clock, the suprachiasmatic nuclei, receives environmental inputs, namely the light-dark cycle, through photopigments located in the eye and from melanopsin-expressing retinal ganglion cells. The authors investigated the influence of light wavelength and intensity on the synchronizati...

journal_title：Journal of biological rhythms

authors： Perret M,Gomez D,Barbosa A,Aujard F,Théry M

更新日期：2010-06-01 00:00:00