Abstract:
BACKGROUND:Naphthoquinone is a class of phenolic compounds derived from naphthalene. 7-Methyljuglone (7-MJ) is a naphthoquinone also known as ramentaceone or 6-Methyl-8-hydroxy-1,4-naphthoquinone or 5-Hydroxy-7-methyl-1,4-naphthoquinone or 7-Methyl-5-hydroxy-1,4-naphthoquinone or 5-Hydroxy-7-methyl-,1,4-naphtoquinone or 7-Methyl-5-hydroxynaphthalene-1,4-dione. This compound is a biologically active naphtoquinone, with a molecular weight of 188 g/mol mostly isolated in the genus Diospyros and Euclea. OBJECTIVES:This review was aimed at providing available chemically and pharmacological data on 7-MJ. METHODS:The chemical and pharmacological data were retrieved from the well-known scientific websites such as Pubmed, Google Scholar, Reaxys, Scirus, Scopus, Sciencedirect, Web-of-knowledge and Scifinder. RESULTS:7-MJ was reported to have a variety of pharmacological activities such as antibacterial, antifungal, anticancer, antitubercular, anti-inflammatory and antiviral activities. The hemi-synthesis of the compound have been described. CONCLUSIONS:The present review pooled out together the knowledge on 7-MJ, and can serve as the start point for future research and valorization accomplishments.
journal_name
Afr Health Scijournal_title
African health sciencesauthors
Mbaveng AT,Kuete Vdoi
10.4314/ahs.v14i1.31subject
Has Abstractpub_date
2014-03-01 00:00:00pages
201-5issue
1eissn
1680-6905issn
1729-0503pii
jAFHS.v14.i1.pg201journal_volume
14pub_type
杂志文章,评审abstract:BACKGROUND:Over a third of the world's population is infected with the tuberculin bacteria. In 1993 WHO launched the DOTS-strategy to enhance treatment compliance. Despite Gambia's adaption in 1985 it falls below WHO target of 85% cure rate. The defaulter rate was 14% in 2001, which reached 16% in the urban areas of th...
journal_title:African health sciences
pub_type: 杂志文章
doi:
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abstract:BACKGROUND:Despite the slight progress made on Antenatal Care (ANC) utilization, skilled delivery care service utilization in Ethiopia is still far-below any acceptable standards. Only 10% of women receive assistance from skilled birth attendants either at home or at health institutions, and as a result the country is ...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v14i4.29
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abstract:Background:Hospital-acquired infections (HAIs), one of the leading causes of, morbidity and mortality, are common in developing countries. Methicillin-resistant staphylococcus aureus (MRSA), commonest cause of HAIs, has been isolated from the hands of more than half of health care workers. Practice of hand hygiene may ...
journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v18i1.11
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journal_title:African health sciences
pub_type: 杂志文章,评审
doi:
更新日期:2011-09-01 00:00:00
abstract:Background:Propofol is administered as intermittent boluses to achieve deep sedation to facilitate oesophagogastroduodenoscopy. Target controlled infusion (TCI) can be employed for this purpose. Methods:176 adults were randomly allocated into two groups of 88 patients. Control group: Received an initial bolus of propo...
journal_title:African health sciences
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journal_title:African health sciences
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doi:10.4314/ahs.v15i4.8
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journal_title:African health sciences
pub_type: 杂志文章,随机对照试验
doi:10.4314/ahs.v14i1.11
更新日期:2014-03-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v11i3.70075
更新日期:2011-08-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v15i4.38
更新日期:2015-12-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
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journal_title:African health sciences
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
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journal_title:African health sciences
pub_type: 杂志文章
doi:10.4314/ahs.v19i4.6
更新日期:2019-12-01 00:00:00
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journal_title:African health sciences
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doi:10.4314/ahs.v17i2.9
更新日期:2017-06-01 00:00:00
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pub_type: 杂志文章
doi:10.4314/ahs.v18i1.21
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journal_title:African health sciences
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doi:10.4314/ahs.v17i1.21
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pub_type: 杂志文章
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更新日期:2019-06-01 00:00:00
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journal_title:African health sciences
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pub_type: 杂志文章
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更新日期:2019-03-01 00:00:00
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更新日期:2020-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-03-01 00:00:00
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journal_title:African health sciences
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doi:10.4314/ahs.v14i3.17
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