Abstract：
:Total RNA was extracted from 15-day-old whole rat brains. Microinjection of the RNA into Xenopus laevis oocytes induced electrophysiological responsiveness to cholecystokinin-8 (CCK) and bombesin (BBS) but not to corticotropin-releasing factor (CRF) or somatostatin. The responses to CCK and BBS were similar in shape, time course, and reversal potential to that induced by receptor mediated phospholipid breakdown and that which is induced by intracellular injection of IP3. These responses were not blocked by atropine or by mianserin, did not require extracellular Ca2+ and were completely suppressed by intracellular injection of EGTA.
journal_name
Brain Resjournal_title
Brain researchauthors
Moriarty TM,Gillo B,Sealfon S,Roberts JL,Blitzer RD,Landau EMdoi
10.1016/0169-328x(88)90021-6subject
Has Abstractpub_date
1988-08-01 00:00:00pages
75-9issue
1eissn
0006-8993issn
1872-6240journal_volume
464pub_type
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