Factors Influencing the Diagnostic Accuracy of Acoustic Radiation Force Impulse Elastography in Patients with Chronic Hepatitis B.

Abstract:

BACKGROUND/AIMS:To determine factors predictive of discordance in staging liver fibrosis using liver biopsy (LB) and acoustic radiation force impulse (ARFI) elastography in patients with chronic hepatitis B (CHB). METHODS:Consecutive patients with CHB who underwent LB and ARFI elastography on the same day from November 2010 to March 2013 were prospectively recruited from three tertiary hospitals. RESULTS:We analyzed 105 patients (median age of 47 years). The F0-1, F2, F3, and F4 fibrosis stages were identified in 27 (25.7%), 27 (25.7%), 21 (20.0%), and 30 (28.6%) patients, respectively. The areas under the receiver operating characteristics curves for ARFI elastography in assessing ≥ F2, ≥ F3, and F4 was 0.814, 0.848, and 0.752, respectively. The discordance of at least one stage between LB and ARFI was observed in 68 patients (64.8%) and of at least two stages in 16 patients (15.2%). In a multivariate analysis, advanced fibrosis stage (F3-4) was the only factor that was negatively correlated with one-stage discordance (p=0.042). Moreover, advanced fibrosis stage was negatively (p=0.016) correlated and body mass index (BMI) was positively (p=0.006) correlated with two-stage discordance. CONCLUSIONS:Advanced fibrosis stage (F3-4) was a predictor of nondiscordance between LB and ARFI elastography; BMI also influenced the accuracy of ARFI elastography.

journal_name

Gut Liver

journal_title

Gut and liver

authors

Park MS,Kim SW,Yoon KT,Kim SU,Park SY,Tak WY,Kweon YO,Cho M,Kim BK,Park JY,Kim DY,Ahn SH,Han KH

doi

10.5009/gnl14391

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

275-82

issue

2

eissn

1976-2283

issn

2005-1212

pii

gnl14391

journal_volume

10

pub_type

杂志文章
  • Weight Loss as a Nonpharmacologic Strategy for Erosive Esophagitis: A 5-Year Follow-up Study.

    abstract:Background/Aims:Obesity is a risk factor for gastroesophageal reflux disease (GERD), with several studies demonstrating positive associations between body mass index (BMI) and GERD symptoms. However, little is known about the effect of BMI changes on erosive esophagitis (EE). In this study, we investigated whether BMI ...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl18148

    authors: Bang KB,Park JH

    更新日期:2018-11-15 00:00:00

  • Causes, Features, and Outcomes of Drug-Induced Liver Injury in 69 Children from China.

    abstract:BACKGROUND/AIMS:Drug-induced liver injury (DILI) is a frequent cause of pediatric liver disease; however, the data on DILI are remarkably limited. METHODS:All 69 children hospitalized with DILI between January 2009 and December 2011 were retrospectively studied. RESULTS:A total of 37.7% of the children had medical hi...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl14184

    authors: Zhu Y,Li YG,Wang JB,Liu SH,Wang LF,Zhao YL,Bai YF,Wang ZX,Li JY,Xiao XH

    更新日期:2015-07-01 00:00:00

  • Direct Acting Antiviral Agents in Korean Patients with Chronic Hepatitis C and Hemophilia Who Are Treatment-Naïve or Treatment-Experienced.

    abstract:Background/Aims:Chronic hepatitis C (CHC) is a major comorbidity in patients with hemophilia. Methods:Patients (n=30) were enrolled between September 2015 and April 2016. Twenty-six patients were genotype 1 (1b, n=21; 1a, n=5) and four patients were genotype 2a/2b. Among 21 patients with genotype 1b, Y93H resistance-a...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl17209

    authors: Lee HW,Yoo KY,Won JW,Kim HJ

    更新日期:2017-09-15 00:00:00

  • Efficacy of Current Traction Techniques for Endoscopic Submucosal Dissection.

    abstract::This systematic review aimed to assess the efficacy of the current approach to tissue traction during the endoscopic submucosal dissection (ESD) of superficial esophageal cancer, early gastric cancer, and colorectal neoplasms. We performed a systematic electronic literature search of articles published in PubMed and s...

    journal_title:Gut and liver

    pub_type: 杂志文章,评审

    doi:10.5009/gnl19266

    authors: Abe S,Wu SYS,Ego M,Takamaru H,Sekiguchi M,Yamada M,Nonaka S,Sakamoto T,Suzuki H,Yoshinaga S,Matsuda T,Oda I,Saito Y

    更新日期:2020-11-15 00:00:00

  • Remission of cap polyposis maintained for more than three years after infliximab treatment.

    abstract::Cap polyposis is a rare disorder with characteristic endoscopic and histological features; its etiology is still unknown, and no specific treatment has been established. We report a case of cap polyposis that improved remarkably after infliximab infusion and had no recurrence for 3 years. ...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2009.3.4.325

    authors: Kim ES,Jeen YT,Keum B,Seo YS,Chun HJ,Um SH,Kim CD,Ryu HS

    更新日期:2009-12-01 00:00:00

  • Solitary synchronous metastatic gastric cancer arising from t1b renal cell carcinoma: a case report and systematic review.

    abstract::Metastasis to the stomach from renal cell carcinoma (RCC) is extremely rare. Usually, gastric metastasis seems to be a late event in patients with RCC and is accompanied by disseminated tumor spread to other organs. Solitary synchronous gastric metastasis from small, localized RCC has rarely been reported. We report a...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2012.6.3.388

    authors: Kim MY,Jung HY,Choi KD,Song HJ,Lee JH,Kim DH,Choi KS,Kim SA,Lee GH,Kim JH

    更新日期:2012-07-01 00:00:00

  • Bile Acid Transporters Are Expressed and Heterogeneously Distributed in Rat Bile Ducts.

    abstract:Background/Aims:Cholangiocytes are capable of reabsorbing bile salts from bile, but the pathophysiological significance of this process is unclear. To this end, we detected the expression and distribution of bile acid transport proteins in cholangiocytes from normal rat liver and analyzed the possible pathophysiologica...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl18265

    authors: Luo ZL,Cheng L,Wang T,Tang LJ,Tian FZ,Xiang K,Cui L

    更新日期:2019-09-15 00:00:00

  • Navigating the Microbial Basis of Inflammatory Bowel Diseases: Seeing the Light at the End of the Tunnel.

    abstract::Inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, are chronic inflammatory conditions affecting the gastrointestinal tract with variable presentations and disease courses. The cause of IBD is unknown, but it is hypothesized that individuals with a genetic predisposition to disease deve...

    journal_title:Gut and liver

    pub_type: 杂志文章,评审

    doi:10.5009/gnl15491

    authors: Raffals LE,Chang EB

    更新日期:2016-07-15 00:00:00

  • Predictive Factors for Severe Outcomes in Ischemic Colitis.

    abstract:BACKGROUND/AIMS:Ischemic colitis includes a wide clinical spectrum ranging from mild to severe forms. This study aimed to determine the factors that are related to the occurrence of severe ischemic colitis. METHODS:This multicenter study was conducted retrospectively in Korea. The patients were divided into mild and s...

    journal_title:Gut and liver

    pub_type: 杂志文章,多中心研究

    doi:10.5009/gnl15167

    authors: Choi SR,Jee SR,Song GA,Park SJ,Lee JH,Song CS,Park HU

    更新日期:2015-11-23 00:00:00

  • Astaxanthin Inhibits Proliferation of Human Gastric Cancer Cell Lines by Interrupting Cell Cycle Progression.

    abstract:BACKGROUND/AIMS:Astaxanthin is a carotenoid pigment that has antioxidant, antitumoral, and anti-inflammatory properties. In this in vitro study, we investigated the mechanism of anticancer effects of astaxanthin in gastric carcinoma cell lines. METHODS:The human gastric adenocarcinoma cell lines AGS, KATO-III, MKN-45,...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl15208

    authors: Kim JH,Park JJ,Lee BJ,Joo MK,Chun HJ,Lee SW,Bak YT

    更新日期:2016-05-23 00:00:00

  • Incidence of Cholangiocarcinoma with or without Previous Resection of Liver for Hepatolithiasis.

    abstract:BACKGROUND/AIMS:To investigate the incidence of cholangiocarcinoma in patients with hepatolithiasis with or without previous resection of liver. METHODS:From 2002 to 2009, we retrospectively reviewed 117 patients who were diagnosed and treated for hepatolithiasis in Korea University Guro Hospital. Among the 117 patien...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2013.7.4.475

    authors: Lee JY,Kim JS,Moon JM,Lim SA,Chung W,Lim EH,Lee BJ,Park JJ,Bak YT

    更新日期:2013-07-01 00:00:00

  • Diagnostic dilemma in an unusual case of common bile duct obstruction.

    abstract::Biliary obstructions are rarely caused by a foreign body and have received sparse attention. We present an unusual case with pruritis and abdominal pain caused by impacted full length surgical gauze within the common bile duct. The patient had previously undergone an open cholecystectomy. Radiological investigations w...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2011.5.2.245

    authors: Bhandari V,Singh M,Vyas HG,Sharma N,Chejara R

    更新日期:2011-06-01 00:00:00

  • Characterization and Prognostic Value of Mutations in Exons 5 and 6 of the p53 Gene in Patients with Colorectal Cancers in Central Iran.

    abstract:BACKGROUND/AIMS:We aimed to investigate the relation-ships among various mutations of the p53 gene and their protein products, histological characteristics, and disease prognosis of primary colorectal cancer in Isfahan, central Iran. METHODS:Sixty-one patients with colorectal adenocarcinoma were enrolled in the study....

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2013.7.3.295

    authors: Golmohammadi R,Namazi MJ,Nikbakht M,Salehi M,Derakhshan MH

    更新日期:2013-05-01 00:00:00

  • Knowledge Gaps among Physicians Caring for Multiethnic Populations at Increased Gastric Cancer Risk.

    abstract:Background/Aims:Although gastric cancer (GC) prevalence in the United States overall is low, there is significantly elevated risk in certain racial/ethnic groups. Providers caring for high-risk populations may not be fully aware of GC risk factors and may underestimate the potential for selective screening. Our aim was...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl17091

    authors: Shah SC,Itzkowitz SH,Jandorf L

    更新日期:2018-01-15 00:00:00

  • Enteroscopy in Crohn's Disease: Are There Any Changes in Role or Outcomes Over Time? A KASID Multicenter Study.

    abstract:Background/Aims:Although balloon-assisted enteroscopy (BAE) enables endoscopic visualization of small bowel (SB) involvement in Crohn's disease (CD), there is no data on the changes in outcomes over time. We therefore investigated the changes in BAE use on CD patients over different time periods in terms of its role an...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl20023

    authors: Jeon SR,Kim JO,Byeon JS,Yang DH,Ko BM,Goong HJ,Jang HJ,Park SJ,Kim ER,Hong SN,Im JP,Kim SE,Koo JS,Eun CS,Chang DK,Korean Association for the Study of Intestinal Disease(KASID).

    更新日期:2020-07-06 00:00:00

  • Usefulness of Immunohistochemistry for Microsatellite Instability Screening in Gastric Cancer.

    abstract:BACKGROUND/AIMS:The usefulness of immunohistochemistry to screen for the microsatellite instability (MSI) phenotype in gastric cancer remains unclear. Moreover, the prognostic value of MSI phenotypes in gastric cancer has been debated. METHODS:The clinicopathologic parameters and survival outcomes of 203 MSI-high (MSI...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl15133

    authors: Bae YS,Kim H,Noh SH,Kim H

    更新日期:2015-09-23 00:00:00

  • Visceral obesity as a risk factor for left-sided diverticulitis in Japan: a multicenter retrospective study.

    abstract:BACKGROUND/AIMS:Left-sided diverticulitis is increasing in Japan, and many studies report that left-sided diverticulitis is more likely to be severe. Therefore, it is important to identify the features and risk factors for left-sided diverticulitis. We hypothesized that left-sided diverticulitis in Japan is related to ...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2013.7.5.532

    authors: Yamada E,Ohkubo H,Higurashi T,Sakai E,Endo H,Takahashi H,Uchida E,Tanida E,Izumi N,Kanesaki A,Hata Y,Matsuura T,Fujisawa N,Komatsu K,Maeda S,Nakajima A

    更新日期:2013-09-01 00:00:00

  • An inverse relationship between the expression of the gastric tumor suppressor RUNX3 and infection with Helicobacter pylori in gastric epithelial dysplasia.

    abstract:BACKGROUND/AIMS:This study was performed to determine the association between RUNX3 expression and Helicobacter pylori infection in premalignant gastric lesions. METHODS:We examined 107 patients with gastric epithelial dysplasia who had undergone endoscopic mucosal resection or submucosal dissection. All tissue sample...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2013.7.6.688

    authors: Chung WC,Jung SH,Joo KR,Kim MJ,Youn GJ,Kim Y,Lee JS,Lee H,Jung JH,Lee YK

    更新日期:2013-11-01 00:00:00

  • The Immunohistochemical Expression of STAT3, Bcl-xL, and MMP-2 Proteins in Colon Adenoma and Adenocarcinoma.

    abstract:BACKGROUND/AIMS:Signal transducers and activators of transcription (STATs) are a family of transcription factors that are activated in response to cytokines and growth factors. STAT3 activation has been implicated in modulating the activity of downstream mediators, such as Bcl-xL and matrix metalloproteinase-2 (MMP-2)....

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2012.6.1.45

    authors: Lee SW,Ahn YY,Kim YS,Kang SB,Nam SW,Lee DS,Jeong HY,Kim JM

    更新日期:2012-01-01 00:00:00

  • Clinical Implication and Risk Factors for Malignancy of Atypical Gastric Gland during Forceps Biopsy.

    abstract:Background/Aims:Although forceps biopsy is performed for suspicious gastric tumors during endoscopy, it is difficult to determine treatment strategies for atypical gastric glands due to uncertainty of the diagnosis. The aim of this study was to investigate clinical implications and risk factors for predicting malignanc...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl18006

    authors: Kim MS,Kim SG,Chung H,Kim J,Hong H,Lee HJ,Kim HJ,Kim MA,Kim WH,Jung HC

    更新日期:2018-09-15 00:00:00

  • Effect of biofeedback therapy in constipation according to rectal sensation.

    abstract:BACKGROUND/AIMS:The pathophysiologic mechanism of rectal hyposensitivity (RH) is not well documented, and the significance of RH in biofeedback therapy (BFT) has not been evaluated. Thus, we aimed to assess the effect of BFT in constipated patients according to the presence of RH. METHODS:Five hundred and ninety const...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2013.7.2.157

    authors: Ahn JY,Myung SJ,Jung KW,Yang DH,Koo HS,Seo SY,Yoon IJ,Kim KJ,Ye BD,Byeon JS,Jung HY,Yang SK,Kim JH

    更新日期:2013-03-01 00:00:00

  • Comparison of Indomethacin, Diclofenac and Aspirin-Induced Gastric Damage according to Age in Rats.

    abstract:BACKGROUND/AIMS:Aging gastric mucosa is known to have decreased mucosal defenses and increased susceptibility to injury by nonsteroidal anti-inflammatory drugs. Depending on the type of nonsteroidal anti-inflammatory drug (NSAID), the underlying mechanisms and the extent of damage to the stomach or intestine may differ...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2012.6.2.210

    authors: Seo PJ,Kim N,Kim JH,Lee BH,Nam RH,Lee HS,Park JH,Lee MK,Chang H,Jung HC,Song IS

    更新日期:2012-04-01 00:00:00

  • Simeprevir-Based Triple Therapy with Reduced Doses of Pegylated Interferon α-2a Plus Ribavirin for Interferon Ineligible Patients with Genotype 1b Hepatitis C Virus.

    abstract:Background/Aims:The present study aimed to evaluate the safety and efficacy of simeprevir-based triple therapy with reduced doses of pegylated interferon (PEG-IFN) and ribavirin for interferon (IFN) ineligible patients, such as elderly and/or cirrhotic patients, and to elucidate the factors contributing to a sustained ...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl16525

    authors: Tamai H,Ida Y,Kawashima A,Shingaki N,Shimizu R,Moribata K,Nasu T,Maekita T,Iguchi M,Kato J,Nakao T,Kitano M

    更新日期:2017-07-15 00:00:00

  • The clinicopathological features of gastric hyperplastic polyps with neoplastic transformations: a suggestion of indication for endoscopic polypectomy.

    abstract:BACKGROUND/AIMS:Although gastric hyperplastic polyps are usually considered as benign lesions, a low risk of carcinomatous conversion is currently recognized. We aimed to identify the characteristics of hyperplastic polyps undergoing neoplastic transformation. METHODS:A total of 269 gastric hyperplastic polyps from 21...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2009.3.4.271

    authors: Han AR,Sung CO,Kim KM,Park CK,Min BH,Lee JH,Kim JY,Chang DK,Kim YH,Rhee PL,Rhee JC,Kim JJ

    更新日期:2009-12-01 00:00:00

  • The Performance of Multiple Transgastric Procedures Using the Natural Orifice Transluminal Endoscopic Surgery Technique: Is Pure NOTES Satisfactory?

    abstract:BACKGROUND/AIMS:Although several groups have demonstrated the usefulness of natural orifice transluminal endoscopic surgery (NOTES), there is still concern about frequent serious adverse events. We performed this study to determine the technical feasibility and safety of pure NOTES with a transgastric approach in a por...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2012.6.4.457

    authors: Song TJ,Seo DW,Kim SH,Park DH,Lee SS,Lee SK,Kim MH

    更新日期:2012-10-01 00:00:00

  • Comparison of Clinical Outcomes of Borderline Resectable Pancreatic Cancer According to the Neoadjuvant Chemo-Regimens: Gemcitabine versus FOLFIRINOX.

    abstract:Background/Aims:Although many studies have reported the promising effect of neoadjuvant treatment for borderline resectable pancreatic cancer (BRPC) to increase resectability, only a few studies have recommended the use of firstline chemotherapeutic agents as neoadjuvant treatment for BRPC. The current study compared c...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl20070

    authors: Choi YJ,Byun Y,Kang JS,Kim HS,Han Y,Kim H,Kwon W,Oh DY,Paik WH,Lee SH,Ryu JK,Kim YT,Lee K,Kim H,Chie EK,Jang JY

    更新日期:2020-08-26 00:00:00

  • A case of esophageal intramural pseudodiverticulosis.

    abstract::Esophageal intramural pseudodiverticulosis (EIP) is a rare benign disease that is characterized by multiple tiny flask-shaped outpouching lesions of the esophageal wall. The etiology is unknown, but the pathologic findings include dilatation of excretory ducts of submucosal glands. The predominant symptom is dysphagia...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2011.5.1.93

    authors: Chon YE,Hwang S,Jung KS,Lee HJ,Lee SG,Shin SK,Lee YC

    更新日期:2011-03-01 00:00:00

  • Hepatic Steatosis Index in the Detection of Fatty Liver in Patients with Chronic Hepatitis B Receiving Antiviral Therapy.

    abstract:Background/Aims:The hepatic steatosis index (HSI) is a noninvasive method to assess the severity of hepatic steatosis. Antiviral therapy (AVT) can impact aspartate aminotransferase and alanine aminotransferase levels, which are the main components of the HSI. Thus, we investigated the accuracy of the HSI in detecting h...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl19301

    authors: Chang JW,Lee HW,Kim BK,Park JY,Kim DY,Ahn SH,Han KH,Kim SU

    更新日期:2021-01-15 00:00:00

  • Long-term outcome of photodynamic therapy with systemic chemotherapy compared to photodynamic therapy alone in patients with advanced hilar cholangiocarcinoma.

    abstract:BACKGROUND/AIMS:Patients with cholangiocarcinoma usually present at an advanced stage, and more than 50% of cases are not resectable at the time of diagnosis. Recently, photodynamic therapy (PDT) has been proposed as a palliative and neoadjuvant modality. We evaluated whether combination of PDT and chemotherapy is more...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl.2014.8.3.318

    authors: Hong MJ,Cheon YK,Lee EJ,Lee TY,Shim CS

    更新日期:2014-05-01 00:00:00

  • Does lymphocytic colitis always present with normal endoscopic findings?

    abstract:BACKGROUND/AIMS:Although normal endoscopic findings are, as a rule, part of the diagnosis of microscopic colitis, sev-eral cases of macroscopic lesions (MLs) have been reported in collagenous colitis, but hardly in lymphocytic colitis (LC). The aim of this study was to investigate the endoscopic, clini-cal, and histopa...

    journal_title:Gut and liver

    pub_type: 杂志文章

    doi:10.5009/gnl13373

    authors: Park HS,Han DS,Ro YO,Eun CS,Yoo KS

    更新日期:2015-03-01 00:00:00