Abstract：
:Over the last two decades virus-like particles (VLPs) have become an important tool in biomedical research and medicine. VLPs are multiprotein structures that resemble viable virus particles in conformation but lack the viral genome. Consequently, they are non-infectious and non-replicative, but retain the ability to penetrate cells, making them useful for a vast spectrum of applications. Above all, VLPs mimicking genuine viruses in antigenic structure provide a safe alternative to attenuated and inactivated viruses in vaccine development. Moreover, due to their transducing proprieties, VLPs may efficiently deliver foreign nucleic acids, proteins, or conjugated compounds to the organism, or even to specific cell types. Additionally, VLPs are versatile nanovectors due to their flexibility in terms of composition and expression systems. In this review, different approaches for of virus-like particle synthesis and manipulation, as well as their potential applications, will be discussed.
journal_name
Pol J Microbioljournal_title
Polish journal of microbiologyauthors
Naskalska A,Pyrć Ksubject
Has Abstractpub_date
2015-01-01 00:00:00pages
3-13issue
1eissn
1733-1331issn
2544-4646journal_volume
64pub_type
杂志文章,评审abstract：:The influence of free base of quinolinilporphyrin and its Zn complex on infectivity of lactophages E3, E5 and E17 has been studied. The results of our investigations show that inhibition of lactophage activity by Zn complex of quinolinilporphyrin at concentration 10 microM and 20 microM was in the range 53-62% and 65-...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:In vitro studies aimed at studying the mechanism of action of carvacrol and oregano as natural anti-bacterial agents to control multiple antibiotic-resistant avian pathogenic Escherichia coli (APEC) strain O23:H52 isolated from chicken were performed. Derivatives with increased minimum inhibitory concentrations (MIC) ...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.33073/pjm-2020-003
更新日期：2020-01-01 00:00:00
abstract：:The use of microbial exopolysaccharides (EPS) in the food, pharmaceutical, and chemical industries has steadily increased during the past decade. A bioactive EPS producing microorganism, Streptomyces nasri was isolated from Kuwait tropical soil and the proteopolysaccharide was tested for its antimicrobial activity. Th...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:The composition of vagina lactic acid bacteria (LAB) differs within the different ethnic group. This study is aimed at determining the prevalence of LAB with their antimicrobial properties in Nigerian women's vagina during different stages of the menstrual cycle. Microorganisms were isolated from vaginal swabs of ten ...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.33073/pjm-2019-020
更新日期：2019-01-01 00:00:00
abstract：:The aim of this study was to develop a non-invasive diagnostic test for the detection of Helicobacter pylori in stool samples from digestive symptomatic patients, using a new protocol of nested-qPCR. A total of 143 patients were invited to participate in the study. A gastric biopsy of each patient was collected for Ra...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.5604/01.3001.0011.5881
更新日期：2018-03-09 00:00:00
abstract：:Repetitive element polymorphism-PCR (REP-PCR) is one of the tools that has been used to elucidate genetic diversity of related microorganisms. Using the MB1 primer, REP-PCR fingerprints from 110 Bacillus strains within the "B. cereus group" have identified eighteen distinct categories, while other more distantly relat...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:The application of DNA-based methods enables to identify Yersinia enterocolitica carrying the ail-gene with a greater sensitivity compared to culture methods and biochemical tests used for detection of pathogenic Y. enterocolitica in animal and food samples. In this study, 100 samples of pig tonsils were examined, amo...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.21307/pjm-2018-023
更新日期：2018-06-30 00:00:00
abstract：:Four ethanologenic ethanol-tolerant yeast strains, Saccharomyces cerevisiae (ATKU132), Saccharomycodes ludwigii (ATKU47), and Issatchenkia orientalis (ATKU5-60 and ATKU5-70), were isolated by an enrichment technique in yeast extract peptone dextrose (YPD) medium supplemented with 10% (v/v) ethanol at 30°C. Among non-S...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2012-09-28 00:00:00
abstract：:It is estimated that one third of the world's population have latent tuberculosis infection and that this is a significant reservoir for future tuberculosis cases. Most cases occur within two years following initial infection. The identification of individuals with latent tuberculosis infection is difficult due to the...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.5604/17331331.1234987
更新日期：2017-03-30 00:00:00
abstract：:Pseudomonas aeruginosa has emerged as a major healthcare associated pathogen that creates a serious public health disaster in both developing and developed countries. In this work we aimed at studying the occurrence of metallo-beta-lactamase (MBL) producing P. aeruginosa in a healthcare setting in Alexandria, Egypt. T...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.5604/01.3001.0010.4855
更新日期：2017-09-27 00:00:00
abstract：:Ixodes ricinus and other representatives of the order Ixodida are vectors of typical pathogens: Borrelia burgdorferi sensu lato, Anaplasma phagocytophilium, Babesia spp., a tick-borne encephalitis virus, and other microorganisms which are important from a medical and veterinary point of view. The presented study focus...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2012-09-28 00:00:00
abstract：:Despite the enormous progress in understanding the process of bacterial pathogenesis and interactions of pathogens with eucaryotic cells the infectious diseases still remain the main cause of human premature deaths. It is now recognized that Helicobacter pylori infects about half of the world's population. Based on re...
journal_title：Polish journal of microbiology
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
abstract：:In this work evaluation of usefulness of monoclonal antibodies (MAbs) CCH2 and AAC10 directed against early--pUL44(DB52) and late--ppUL83(pp65) CMV antigens, utilized in Department of Virology, NIH for routine diagnosis of CMV infection by shell vial and pp65 antigenemia assay, for determination of CMV antigens by flo...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:The aim of this study was to determine if there are quantitative differences in Candida fungi between pediatric patients with Crohn's disease (before and after exclusive enteral nutrition (EEN), and the biologic therapy with anti-tumor necrosis factor alpha - (IFX)), and healthy controls. DNA was isolated from fecal s...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.21307/pjm-2019-014
更新日期：2019-01-01 00:00:00
abstract：:Quorum sensing (QS), or cell-to-cell communication in bacteria, is achieved through the production and subsequent response to the accumulation of extracellular signal molecules called autoinductors. The main role of QS is regulation of production of virulence factors in bacteria. Bacterial pathogenicity is often manif...
journal_title：Polish journal of microbiology
pub_type： 杂志文章,评审
doi：
更新日期：2009-01-01 00:00:00
abstract：:Biofilm forming multidrug resistant Staphylococcus spp. are major reservoirs for transmission of ophthalmic infections. They were isolated from ocular patients suffering from conjunctivitis. In this study we analyzed biofilm forming ability, antibiotic resistance profile of the Staphylococcus spp. isolated from clinic...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:Abortion in small ruminants is a significant problem in Iraq and causes severe economic losses in sheep farms. Chlamydia abortus causes enzootic abortion in ewes and is associated with reproductive problems in sheep in Sulaimani province - Northern Iraq. During a lambing season in 2017, abortion was widespread among s...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.33073/pjm-2020-009
更新日期：2020-01-01 00:00:00
abstract：:The antibacterial activities of five antibiotics, three brands of Ofloxacins (Obenasin, Floxavid and Drovid) and two brands of Ciprofloxacins (Uroxin and Siprosan), and five commonly used disinfectants (Lysol, Dettol, Purit, Roberts and Wex-cide) against Staphylococcus aureus, Escherichia coli, Proteus spp., Pseudomon...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Paeonia ostii is known for its excellent medicinal values as Chinese traditional plant. To date, the diversity of culturable endophytes associated with P. ostii is in its initial phase of exploration. In this study, 56 endophytic bacteria and 51 endophytic fungi were isolated from P. ostii roots in China. Subsequent c...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.21307/pjm-2018-052
更新日期：2018-01-01 00:00:00
abstract：:Mollusk shells provide a hard substrate for aquatic biofilm colonization. While most work has focused on bivalve shells and grazing, little work has focused on gastropod shells and the microbes growing on them. We sampled biofilms from 14 Pleuroceracanaliculatum and analyzed them using a metagenomic approach. Microbia...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2015-01-01 00:00:00
abstract：:The aim of this study was to compare the prevalence of EBV genotype and del-LMP-1 in saliva from Polish, Taiwanese and Arabic healthy students. The study group consisted of 56 healthy students; 24 of them Polish, 25 Taiwanese, and 7 Arabic. Typing was carried out using PCR with EBNA-2 primers. A detection of LMP-1 var...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：:Coxiella burnetii is the etiologic agent of Q fever, a worldwide distributed zoonosis, accountable for serious health problem both for humans and animals. The exposure to C. burnetii infected animals and their products is the main risk factor for Q fever in humans. Several outbreaks of Q fever have been described in P...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:The caecal chyme of pigs was incubated anaerobically in McDougall buffer with and without fumonisin B1 (5 μg/ml) for 0, 24 and 48 h. The plate count agar technique was applied for enumerating the amount of bacteria including aerobic, anaerobic bacteria, coliform, Escherichia coli and Lactobacillus sp. The quantitative...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.5604/01.3001.0010.7858
更新日期：2017-07-06 00:00:00
abstract：:Pathogenicity and ultrastructural investigation of the inoculation of peppermint stems and rhizomes with Phoma strasseri conidia was undertaken using scanning and transmission electron microscopy to examine the host-parasite relationship. Pathogenicity experiments demonstrated that all tested P. strasseri isolates had...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:The aim of the study was evaluation of qualitative and quantitative changes in bacterial ecosystem in 109 children with inflammatory bowel diseases. Stools obtained from patients were analysed for selected bacteria and concentration of faecal inflammatory markers (calprotectin, lactoferrin, M2-PK). The number of selec...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：:Growing cultures of the green obligate photolithotroph, Chlorobaculum parvum DSM 263T (formerly Chlorobium vibrioforme forma specialis thiosulfatophilum NCIB 8327), oxidized sulfide quantitatively to elemental sulfur, with no sulfate formation. In the early stages of growth and sulfide oxidation, the sulfur product be...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:The effects of inorganic nutrients (N, P) enrichment of mesotrophic lake water on changes in bacterial and protistan (heterotrophic nanoflagellates and ciliates) communities compositions were studied in the mesocosm experiment. Phosphorus (PO4(3-)) and nitrogen (NH4+) alone and in combination were added to three types...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:Unravelling of the interplay between the immune system and non-diphtheria corynebacteria would contribute to understanding their increasing role as medically important microorganisms. We aimed at the analysis of pro- (TNF, IL-1β, IL-6, IL-8, and IL-12p70) and anti-inflammatory (IL-10) cytokines produced by Jurkat T ce...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.33073/pjm-2019-045
更新日期：2019-12-01 00:00:00
abstract：:The economic losses caused by postharvest fruits diseases have attracted global attention. Traditional chemical fungicide could not meet the need of humans. In recent years, microbial agent which has begun to take the place of chemical fungicide comes into people's vision. The aim of this paper was to investigate the ...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：10.5604/17331331.1204476
更新日期：2016-06-07 00:00:00
abstract：:Many bacterial species can be a cause of various heart diseases, such as: Borrelia burgdorferi sensu lato, Coxiella burnetii and Bartonella spp. The aim of the present studies was to establish if any tick-borne infections can contribute to serious heart disorders resulting in the need for heart transplantation. Myocar...
journal_title：Polish journal of microbiology
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
