Abstract:
:The microvasculature and macrovasculature undergo extensive, organ-specific perinatal maturation. Multiple studies show associations between low birth weight and subsequent cardiovascular dysfunction in adulthood, suggesting that extreme preterm birth interferes with this maturation process. Therefore, we designed PREMATCH (PREMATurity as predictor of Cardiovascular-renal Health) to phenotype the microcirculation and macrocirculation during childhood in former preterm infants. A well-characterized cohort of former extreme preterm birth survivors and gender- and age-matched controls (aged 8-13 years) will be investigated for microvascular and macrovascular structure and function. In addition to cognitive performance and anthropometrics, we will investigate (i) the microvascular structure and function by endothelial function (photoplethysmography), sublingual capillary glycocalyx function (sidestream dark field imaging) and retinal structure (diameters of arterioles and venules); and (ii) the macrovascular phenotype by cardiac and renal ultrasound, repeated blood pressure measurements and arterial pulse-wave recordings. The PREMATCH study is unique in its design, and ongoing recruitment demonstrates excellent feasibility. The expectation is that the results of this study will identify risk factors during childhood for subsequent cardiovascular-renal disease in the adult life of former preterm infants, while further analysis on mediators in neonatal life of this cardiovascular-renal outcome may provide new information on perinatal risk factors.
journal_name
Blood Pressjournal_title
Blood pressureauthors
Raaijmakers A,Petit T,Gu Y,Zhang Z,Wei F,Cools B,Jacobs L,Thijs L,Thewissen L,Levtchenko E,Staessen JA,Allegaert Kdoi
10.3109/08037051.2015.1053220subject
Has Abstractpub_date
2015-01-01 00:00:00pages
275-83issue
5eissn
0803-7051issn
1651-1999journal_volume
24pub_type
临床试验,杂志文章相关文献
BLOOD PRESSURE文献大全abstract:PURPOSE:Event-based clinical outcome trials have shown limited evidence to support guidelines recommendations to lower blood pressure (BP) to <130/80 mmHg in middle-aged and elderly hypertensive patients with diabetes mellitus or with general high cardiovascular (CV) risk. We addressed this issue by post-hoc analysing ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037051.2020.1856642
更新日期:2021-01-06 00:00:00
abstract::Ascending aortic blood pressure-derived indices were shown to be related to coronary atherosclerosis. However, no study so far has analyzed the relation between ascending aortic pulsatility and the extent of coronary atherosclerosis in normotensives. Therefore, the aim of the present analysis was to assess the relatio...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050701428125
更新日期:2007-01-01 00:00:00
abstract:AIMS:To assess safety and efficacy of valsartan/amlodipine combination in hypertensive Taiwanese patients. METHODS:This 12-week, multi-center, prospective, observational, post-marketing study enrolled 1029 patients to receive valsartan/amlodipine combination alone or as add-on to other antihypertensives. Efficacy was ...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,多中心研究
doi:10.3109/08037051.2012.697629
更新日期:2012-07-01 00:00:00
abstract:AIMS:The purpose of the study was to assess the effect of percutaneous transluminal coronary angioplasty (PTCA) on plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) level in hypertensive and normotensive subjects with and without systolic left ventricular dysfunction. METHODS AND RESULTS:Forty patients affec...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050600804814
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:The clinical effects of percutaneous transluminal renal artery angioplasty (PTRA) in patients with renal vascular stenosis and hypertension is controversial. METHODS:We consecutively recruited all 23 patients referred for evaluation of renovascular hypertension that eventually underwent unilateral PTRA, to ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050500339275
更新日期:2005-01-01 00:00:00
abstract::Serum uric acid (SUA) but also hemorheological parameters such as hematocrit (Hct) and whole blood viscosity (WBV) are markers of cardiovascular risk. Increased blood cell volume is one of the known causes of hyperuricemia. We therefore aimed to investigate the relationship between SUA and hemorheology in untreated bo...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::It has been reported that the number of circulating endothelial progenitor cells (EPCs) reflects the endogenous vascular repair ability, with the EPCs pool declining in the presence of cardiovascular risk factors. However, their relationship with hypertension and the effects of anti-hypertensive treatment remain uncle...
journal_title:Blood pressure
pub_type: 杂志文章,随机对照试验
doi:10.3109/08037051.2010.535973
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Significant numbers of asymptomatic hypertensive patients are attacked by subclinical target organ damage (TOD) such as proteinuria, left ventricular hypertrophy and carotid atherosclerosis. Platelets become activated in uncontrolled hypertension and play a crucial role in increased thrombotic tendency. Mean...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2010.532317
更新日期:2011-04-01 00:00:00
abstract::This 1-year, dose-titration, General Practitioner (GP) study compared efficacy, tolerability and safety of oral temocapril (10-40 mg once daily) with atenolol (25-100 mg once daily) in mild to moderate adult hypertensives (diastolic blood pressure (DBP) 95-114 mmHg). A 12-week dose-titration period, randomized 3:1 tem...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.3109/08037059709062074
更新日期:1997-07-01 00:00:00
abstract::Medullipin I (Med I) is a vasodepressor prohormone which is continuously elaborated into the renal venous effluent (RVE) of isolated rat kidneys perfused under high pressure. We have improved the yield of Med I by substituting saline for the albumin perfusate previously reported; and considerably improved refinement b...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059409102295
更新日期:1994-11-01 00:00:00
abstract::There is compelling evidence to indicate an important role for increased local renin-angiotensin system activity in the pathogenesis of cardiac hypertrophy and heart failure. Resveratrol is a natural polyphenol that activates SIRT1, a novel cardioprotective and longevity factor having NAD(+)-dependent histone deacetyl...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2010.481808
更新日期:2010-06-01 00:00:00
abstract::The aim of this study was to assess the associations between single nucleotide polymorphisms (SNPs) of the apelin and APJ (apelin receptor) genes and the risk of hypertension in people living in the south-east coastal area of China. A cross-sectional study involving 1031 participants was performed. Genotypes of the ap...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2016.1156905
更新日期:2016-08-01 00:00:00
abstract::BACKGROUND AND AIM. The ratio of deceleration time to early mitral wave velocity (mitral deceleration index, MDI) has been recently shown to predict cardiovascular events more precisely than deceleration time alone in human hypertension. Data, however, about the relationship of this parameter with cardiac structure ar...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2011.553926
更新日期:2011-08-01 00:00:00
abstract::Plasma atrial natriuretic peptide (ANP), plasma and 24-h urine catecholamines, plasma renin activity (PRA), and serum aldosterone were studied in offspring of hypertensive and normotensive families [n = 82; age 37 +/- 7 years (mean +/- SD)]. Despite higher age, higher blood pressure, and higher urine excretion of cate...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059409102261
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND:Orthostatic hypotension (OH) is common amongst the older population and is associated with morbidity and mortality. We sought to investigate predictors of OH to assist the clinician in identifying patients at risk. METHODS AND RESULTS:Database of 2696 patients attending a transient ischaemic attack (TIA) cl...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2012.732780
更新日期:2013-04-01 00:00:00
abstract:OBJECTIVE:To compare unattended blood pressure (BP) with two attended BP, with 24-h ambulatory (ABPM) and central BP measurements in hypertensive patients with (DMs) and without diabetes (HTs). METHODS:In the same hypertension clinic we evaluate 129 consecutive HTs (56% female, 59 + 16 yrs) and 91 DMs (62% female, 64 ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037051.2019.1568184
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:The most common ophthalmologic manifestation of hypertension is hypertensive retinopathy. Our study was designed to evaluate the factors that determine retinal vessel caliber in hypertensive subjects. METHODS:During a 6-month period, retinal photographs were taken of participants during a routine yearly che...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2012.645336
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:To investigate if young normotensive subjects with a familial history of essential hypertension (FHH) or young borderline-hypertensive (BHT) subjects have a defect endothelial function. METHODS:Fifteen young (26 +/- 4 years) healthy normotensive (115 +/- 8/71 +/- 6 mmHg) subjects with a FHH, 31 matched healt...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/080370502320779485
更新日期:2002-01-01 00:00:00
abstract::Low compliance to therapeutic regimens can have serious impact on patient health. A variety of technologies such as tablet dispensers and reminders has been developed to improve compliance. The aim of this study was to assess the acceptance of patients and physicians with regard to the functions and usefulness of a re...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037050903289598
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The lack of nocturnal BP fall less than 10% of the daytime, called non-dipper hypertension, is associated with increased cardiovascular morbidity and mortality. The aim of our study was to investigate atrial conduction time in patients with non-dipper hypertension using electromechanical coupling interval an...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2010.532302
更新日期:2011-02-01 00:00:00
abstract::BACKGROUND. Ganglioneuromas (GNs) are neural crest cell-derived tumors and rarely occur in the adrenal gland. They are usually asymptomatic and hormonally silent. The majority of cases are detected incidentally during work-up for unrelated conditions. Hormone-secreting pure adrenal GNs in adults are extremely rare. To...
journal_title:Blood pressure
pub_type: 杂志文章,评审
doi:10.3109/08037051.2013.796103
更新日期:2014-02-01 00:00:00
abstract::Plasma level of adrenaline has been reported to be elevated in borderline hypertension. However, its role in developing and maintaining hypertension is still not completely understood. This study aimed to estimate the role of plasma adrenaline in developing hypertension. Ten patients with borderline hypertension (BHT)...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059509077578
更新日期:1995-03-01 00:00:00
abstract::The BBB study (Swedish for Behandla Blodtryck Bättre or Treat Blood Pressure Better) was a multicenter trial designed to investigate three aspects of antihypertensive treatment: i) Is it possible to lower the diastolic blood pressure further in "well-treated" hypertensive patients through intensified therapy? ii) Can ...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.3109/08037059409102265
更新日期:1994-07-01 00:00:00
abstract::NORDIL--the Nordic Diltiazem Study (NORDIL)--is a prospective, randomized, open blinded-endpoint (PROBE), multicenter, parallel-group morbidity/mortality outcome study in hypertensive patients designed to compare an intervention strategy based on the calcium antagonist diltiazem with a strategy based on conventional a...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1080/080370599439517
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Endothelial dysfunction plays a major role in erectile dysfunction (ED). Uric acid (UA) is a marker of endothelial dysfunction. We hypothesized that increased UA levels may be associated with ED and aimed to investigate whether there is a relationship between, UA and ED in hypertensive patients. METHODS:A t...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2014.933032
更新日期:2014-12-01 00:00:00
abstract::Purpose: Previous studies that evaluated the prevalence of hypertension in Nigeria were either clinic based, non-standardized or did not include out-of-clinic blood pressure (BP) measurement. Materials and Methods: We selected a rural and an urban community in one state in each of the 6 geopolitical zones of Nigeria. ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037051.2019.1612706
更新日期:2019-08-01 00:00:00
abstract::Arterial hypertension is accompanied by increased morbidity and mortality and constitutes a substantial part of medical care. Antihypertensive intervention reduces the cardiovascular morbidity and mortality. The aims of the study were to evaluate the relationship between cardiovascular risk factors and the blood press...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050050151780
更新日期:2000-01-01 00:00:00
abstract::Several lines of evidence show that metabolic syndrome represents an important therapeutic challenge for the forthcoming years. This is because of the epidemic burden of this multifaceted disease, the adverse impact on cardiovascular risk, as well as the problems posed in its management. This paper will provide an up-...
journal_title:Blood pressure
pub_type: 杂志文章,评审
doi:10.1080/08037050802677695
更新日期:2009-01-01 00:00:00
abstract::We have previously shown that the angiotensin receptor blocker valsartan is associated with a lower incidence of new-onset type 2 diabetes than that with the calcium-channel antagonist amlodipine in the treatment of hypertensive patients at high cardiovascular risk. We have now investigated the benefits of valsartan v...
journal_title:Blood pressure
pub_type: 杂志文章,随机对照试验
doi:10.1080/08037050802169644
更新日期:2008-01-01 00:00:00
abstract::To investigate further the relationship between atherosclerotic vascular disease and blood pressure, and the phenomenon of white coat hypertension, we performed a cross-sectional study of patients referred for carotid Doppler scanning, to determine the relationship between ambulatory blood pressure monitoring (ABPM) a...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/080370599439652
更新日期:1999-01-01 00:00:00