Measurements of angular distributions of Rayleigh and Mie scattering events in biological models.

Abstract:

:Remission spectroscopy in living tissues can only be performed because scattering processes induce a pronounced amount of backscattered light. New types of scattering chambers were constructed in order to investigate the angular distribution of light intensities caused by scattering events typical for living tissues. Different solutions and suspensions containing microspheres, haemoglobin molecules, erythrocytes and liver homogenate were used in order to gain basic information applicable to remission spectrophotometry in tissue. Reflection spectroscopy in biological tissues is only possible because of the scattering properties of the material under observation. Light which penetrates the sample is remitted from the tissue. The remission is caused by the scattering of the light by different biological structures and particles. This scattered light gives information about the optical properties of the particles and structures in an integral form. A scattering chamber for small sample volumes has been developed for measurements of the optical properties of various particles in suspension. Measurements of scattering diagrams from microspheres with an average diameter of 7 microns, artificial particles, haemoglobin solutions, mixtures of microspheres and haemoglobin as well as erythrocytes and mitochondria have been performed. The different optical behaviour of the measured signals is qualitatively discussed.

journal_name

Phys Med Biol

authors

Frank KH,Kessler M,Appelbaum K,Albrecht HP,Mauch ED

doi

10.1088/0031-9155/34/12/012

subject

Has Abstract

pub_date

1989-12-01 00:00:00

pages

1901-16

issue

12

eissn

0031-9155

issn

1361-6560

journal_volume

34

pub_type

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