Abstract:
:The aim of the present study was to compare the clinical characteristics of acute lymphoblastic leukemia (ALL) that occurred in male and female patients at one institution in Southern China. The medical electronic records of Nanfang Hospital, affiliated to Southern Medical University, were searched for patients with a definite diagnosis of ALL that were diagnosed between January 1, 2001 and December 31, 2012. The clinical data of the patients were collected and analyzed. A total of 705 eligible patients were identified. The gender ratio of male to female patients was 1.84:1. The average ages at the time of diagnosis were 16.43 and 19.54 years for male and female patients, respectively (P=0.007). No significant differences were identified in the seasonal occurrence distribution, blood group distribution or ratio for the presence of the Ph chromosome between males and females. However, a higher incidence of T-cell type ALL was identified in males (P=0.023). The present study reveals that ALL demonstrates a male predominance, but similar clinical characteristics of ALL are present in males and females in Southern China.
journal_name
Oncol Lettjournal_title
Oncology lettersauthors
Li SY,Ye JY,Meng FY,Li CF,Yang MOdoi
10.3892/ol.2015.3202subject
Has Abstractpub_date
2015-07-01 00:00:00pages
453-458issue
1eissn
1792-1074issn
1792-1082pii
OL-0-0-3202journal_volume
10pub_type
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