Abstract：
:Immune sera obtained from either BALB/c mice (susceptible) at 7 weeks, or C57BL/6 mice (resistant), at 7 weeks after infection with L. m. amazonensis, were effective in increasing internalization of homologous promastigotes into starch-induced peritoneal macrophages (from both mouse strains). Both the internalization enhancing effect and the levels of anti-leishmanial antibody (ELISA) were removed from sera by absorption with heat-killed promastigotes. Sera at 1/200 dilution obtained from either mouse strain at 2 weeks after infection did not enhance parasite internalization into macrophages. The factors leading to susceptibility or resistance during leishmaniasis do not appear to be related to differences in antibody-mediated opsonic activity.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
Reis MG,Roters SB,Barral-Netto Msubject
Has Abstractpub_date
1987-09-01 00:00:00pages
339-42issue
3eissn
0001-706Xissn
1873-6254journal_volume
44pub_type
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