Potential Efficacy of Pegylated Interferon-α and a Nucleos(t)ide Analogue as Combination Therapy for HBeAg-Positive Chronic Hepatitis B.

abstract：BACKGROUND/AIMS:M2 pyruvate kinase (M2-PK) is an enzyme that is produced in undifferentiated and proliferating tissues. This study aims to evaluate the usefulness of the immunochromatographic M2 pyruvate kinase (iM2-PK) for the screening of colorectal cancer (CRC) and premalignant lesions. METHODS:Healthy volunteers a...

journal_title：Gut and liver

authors： Kim YC,Kim JH,Cheung DY,Kim TH,Jun EJ,Oh JW,Kim CW,Chung WC,Kim BW,Kim SS,Kim JI,Park SH,Kim JK

更新日期：2015-09-23 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fifth most common cancer globally and the fourth most common cancer in men in Korea, where the prevalence of chronic hepatitis B infection is high in middle-aged and elderly patients. These practice guidelines will provide useful and constructive advice for the clinical management...

journal_title：Gut and liver

authors： Korean Liver Cancer Association.,National Cancer Center.

更新日期：2019-05-15 00:00:00

abstract：Background/Aims:Data regarding the prognosis of early esophageal cancer are lacking. This study investigated the long-term outcomes and factors affecting the survival of patients with mucosal esophageal squamous cell carcinoma (T1aESCC). Methods:We analyzed the clinical and tumor-specific parameters of 263 patients wh...

journal_title：Gut and liver

authors： Kim GH,Na HK,Ahn JY,Lee JH,Jung KW,Kim DH,Kim HR,Choi KD,Song HJ,Kim YH,Lee GH,Jung HY,Park SI

更新日期：2021-01-19 00:00:00

abstract：:A 75-year-old Japanese man with chronic hepatitis C was found to have a large liver tumor and multiple nodules in the bilateral lungs. We diagnosed the tumor as hepatocellular carcinoma (HCC) with multiple lung metastases based on imaging studies and high titers of HCC tumor markers. Remarkably, without any anticancer...

journal_title：Gut and liver

authors： Saito T,Naito M,Matsumura Y,Kita H,Kanno T,Nakada Y,Hamano M,Chiba M,Maeda K,Michida T,Ito T

更新日期：2014-09-01 00:00:00

abstract：Background/Aims:Although gastric cancer (GC) prevalence in the United States overall is low, there is significantly elevated risk in certain racial/ethnic groups. Providers caring for high-risk populations may not be fully aware of GC risk factors and may underestimate the potential for selective screening. Our aim was...

journal_title：Gut and liver

authors： Shah SC,Itzkowitz SH,Jandorf L

更新日期：2018-01-15 00:00:00

abstract：:Whether Helicobacter pylori eradication actually reduces the risk of metachronous gastric cancer (MGC) development remains a controversial question. In this review, we addressed this topic by reviewing the results of clinical investigations and molecular pathological analyses of the roles of H. pylori eradication and ...

journal_title：Gut and liver

authors： Watari J,Tomita T,Tozawa K,Oshima T,Fukui H,Miwa H

更新日期：2020-05-15 00:00:00

abstract：BACKGROUND/AIMS:Although gastric hyperplastic polyps are usually considered as benign lesions, a low risk of carcinomatous conversion is currently recognized. We aimed to identify the characteristics of hyperplastic polyps undergoing neoplastic transformation. METHODS:A total of 269 gastric hyperplastic polyps from 21...

journal_title：Gut and liver

authors： Han AR,Sung CO,Kim KM,Park CK,Min BH,Lee JH,Kim JY,Chang DK,Kim YH,Rhee PL,Rhee JC,Kim JJ

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND/AIMS:As the incidence rate of and mortality from pseudomembranous colitis (PMC) are increasing worldwide, it is important to study the simple predictive risk factors for PMC among patients with hospital-acquired diarrhea (HAD). This study focused on identifying the clinical risk factors that can easily predi...

journal_title：Gut and liver

authors： Yang BK,Do BJ,Kim EJ,Lee JU,Kim MH,Kang JG,Kim HS,Kim KH,Jang MK,Lee JH,Kim HY,Shin WG

更新日期：2014-01-01 00:00:00

abstract：:During the past few decades, liver transplant has developed from a high-mortality procedure to an almost routine procedure with good survival outcomes. The development of living donor liver transplant has increased the availability of liver grafts, and the scope of indications for liver transplant has been expanding e...

journal_title：Gut and liver

authors： Chu KK,Wong KH,Chok KS

更新日期：2021-01-15 00:00:00

abstract：:This review article describes morphological aspects, gene abnormalities, and mucin expression profiles in precursor lesions such as pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and mucinous cystic neoplasm (MCN) of the pancreas, as well as their relation to pancreatic d...

journal_title：Gut and liver

authors： Yonezawa S,Higashi M,Yamada N,Goto M

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND/AIMS:The pathophysiologic mechanism of rectal hyposensitivity (RH) is not well documented, and the significance of RH in biofeedback therapy (BFT) has not been evaluated. Thus, we aimed to assess the effect of BFT in constipated patients according to the presence of RH. METHODS:Five hundred and ninety const...

journal_title：Gut and liver

authors： Ahn JY,Myung SJ,Jung KW,Yang DH,Koo HS,Seo SY,Yoon IJ,Kim KJ,Ye BD,Byeon JS,Jung HY,Yang SK,Kim JH

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND/AIMS:Endoscopic submucosal dissection (ESD), a new and potentially curative method for treating gastrointestinal neoplasms, may have longer procedure time and the risk of complications when compared to conventional endoscopic mucosal resection. This study evaluated the efficacy and safety of ESD in patients ...

journal_title：Gut and liver

authors： Kim BJ,Chang TH,Kim JJ,Min BH,Lee JH,Son HJ,Rhee PL,Rhee JC,Kim KM,Park CK

更新日期：2010-06-01 00:00:00

abstract：Background/Aims:We evaluated whether anti-Saccharomyces cerevisiae antibody (ASCA) titers are associated with diagnostic findings, disease activity, Paris classification phenotypes, and persistence after infliximab (IFX) treatment in children with Crohn's disease (CD). We also investigated the role of ASCA as a predict...

journal_title：Gut and liver

authors： Kim MJ,Kim E,Kang B,Lee Y,Kang ES,Choe YH

更新日期：2020-12-30 00:00:00

abstract：:Biliary obstructions are rarely caused by a foreign body and have received sparse attention. We present an unusual case with pruritis and abdominal pain caused by impacted full length surgical gauze within the common bile duct. The patient had previously undergone an open cholecystectomy. Radiological investigations w...

journal_title：Gut and liver

authors： Bhandari V,Singh M,Vyas HG,Sharma N,Chejara R

更新日期：2011-06-01 00:00:00

abstract：Background/Aims:The hepatic steatosis index (HSI) is a noninvasive method to assess the severity of hepatic steatosis. Antiviral therapy (AVT) can impact aspartate aminotransferase and alanine aminotransferase levels, which are the main components of the HSI. Thus, we investigated the accuracy of the HSI in detecting h...

journal_title：Gut and liver

authors： Chang JW,Lee HW,Kim BK,Park JY,Kim DY,Ahn SH,Han KH,Kim SU

更新日期：2021-01-15 00:00:00

abstract：BACKGROUND/AIMS:The notion that acute hepatitis A superimposed on chronic hepatitis B infection leads to a worse outcome than acute hepatitis A alone remains controversial. The aim of this study was to determine the influence of the presence of hepatitis B surface antigen (HBsAg) on the severity of acute hepatitis A. ...

journal_title：Gut and liver

authors： Kim KM,Eo SJ,Gwak GY,Choi MS,Lee JH,Koh KC,Yoo BC,Paik SW

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND/AIMS:Benign bronchoesophageal fistula (BEF) is a rare condition that is usually treated surgically; however, less invasive endoscopy procedures have been attempted to overcome the disadvantages of surgery. The aim of this study was thus to determine the results of endoscopic management as a primary treatment...

journal_title：Gut and liver

authors： Ahn JY,Jung HY,Choi JY,Kim MY,Lee JH,Choi KS,Kim DH,Choi KD,Song HJ,Lee GH,Kim JH

更新日期：2010-12-01 00:00:00

abstract：:Pseudoachalasia secondary to primary squamous cell carcinoma (SCC) of the liver is extremely rare and has not been reported until now. Here, we report a unique case of primary SCC of the liver initially presenting with progressive dysphagia along with short periods of significant weight loss. A 58-year-old man initial...

journal_title：Gut and liver

authors： Choi MK,Kim GH,Song GA,Nam HS,Yi YS,Ahn KH,Kim S,Kim JY,Park DY

更新日期：2012-04-01 00:00:00

abstract：Background/Aims:The present study aimed to evaluate the safety and efficacy of simeprevir-based triple therapy with reduced doses of pegylated interferon (PEG-IFN) and ribavirin for interferon (IFN) ineligible patients, such as elderly and/or cirrhotic patients, and to elucidate the factors contributing to a sustained ...

journal_title：Gut and liver

authors： Tamai H,Ida Y,Kawashima A,Shingaki N,Shimizu R,Moribata K,Nasu T,Maekita T,Iguchi M,Kato J,Nakao T,Kitano M

更新日期：2017-07-15 00:00:00

abstract：BACKGROUND/AIMS:Cytapheresis (CAP) is a novel strategy for ulcerative colitis (UC). However, there is insufficient data on the long-term outcome of UC patients who achieve remission by CAP. This study involved patients with severe UC who refracted to intravenous (iv) corticosteroid. METHODS:Forty-seven UC patients who...

journal_title：Gut and liver

authors： Fukunaga K,Nagase K,Kusaka T,Hida N,Ohda Y,Yoshida K,Tozawa K,Kamikozuru K,Iimuro M,Nakamura S,Miwa H,Matsumoto T

更新日期：2009-03-01 00:00:00

abstract：:Liver transplantation has become a lifesaving procedure for patients who have chronic end-stage liver disease and acute liver failure. The satisfactory outcome of liver transplantation has led to insufficient supplies of deceased donor organs, particularly in East Asia. Hence, East Asian surgeons are concentrating on ...

journal_title：Gut and liver

authors： Moon DB,Lee SG

更新日期：2009-09-01 00:00:00

abstract：:The management of Helicobacter pylori infection in Singapore remains a clinical challenge. Similar to other regions, there has been an increase in antibiotic resistance rates through the years. Nonetheless, over the past two decades, clarithromycin-based triple therapy has continued to be used as the first line treatm...

journal_title：Gut and liver

authors： Ang TL,Ang D

更新日期：2021-01-15 00:00:00

abstract：BACKGROUND/AIMS:Although colorectal endoscopic submucosal dissection (ESD)-related perforation is not uncommon, the factors affecting clinical outcomes after perforation have not been investigated. This study was designed to investigate the factors influencing the clinical course of ESD-related colon perforation. METH...

journal_title：Gut and liver

authors： Kang DU,Choi Y,Lee HS,Lee HJ,Park SH,Yang DH,Yoon SM,Kim KJ,Ye BD,Myung SJ,Yang SK,Kim JH,Byeon JS

更新日期：2016-05-23 00:00:00

abstract：Background/Aims:Chronic hepatitis C (CHC) is a major comorbidity in patients with hemophilia. Methods:Patients (n=30) were enrolled between September 2015 and April 2016. Twenty-six patients were genotype 1 (1b, n=21; 1a, n=5) and four patients were genotype 2a/2b. Among 21 patients with genotype 1b, Y93H resistance-a...

journal_title：Gut and liver

authors： Lee HW,Yoo KY,Won JW,Kim HJ

更新日期：2017-09-15 00:00:00

abstract：BACKGROUND/AIMS:Left-sided diverticulitis is increasing in Japan, and many studies report that left-sided diverticulitis is more likely to be severe. Therefore, it is important to identify the features and risk factors for left-sided diverticulitis. We hypothesized that left-sided diverticulitis in Japan is related to ...

journal_title：Gut and liver

authors： Yamada E,Ohkubo H,Higurashi T,Sakai E,Endo H,Takahashi H,Uchida E,Tanida E,Izumi N,Kanesaki A,Hata Y,Matsuura T,Fujisawa N,Komatsu K,Maeda S,Nakajima A

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND/AIMS:Recent data from Western populations have suggested that patients with sporadic duodenal adenomas are at a higher risk for the development of colorectal neoplasia. In this study, we compared the frequency of colorectal neoplasia in patients with sporadic duodenal adenomas to healthy control subjects. M...

journal_title：Gut and liver

authors： Chung WC,Lee BI,Roh SY,Kwak JW,Hwang SM,Ko YH,Oh JH,Cho H,Chae HS,Cho YS

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND/AIMS:Although several groups have demonstrated the usefulness of natural orifice transluminal endoscopic surgery (NOTES), there is still concern about frequent serious adverse events. We performed this study to determine the technical feasibility and safety of pure NOTES with a transgastric approach in a por...

journal_title：Gut and liver

authors： Song TJ,Seo DW,Kim SH,Park DH,Lee SS,Lee SK,Kim MH

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND/AIMS:The presence of Helicobacter pylori (H. pylori) infection represents a high-risk state of gastric cancer, but the risk is even higher in gastric atrophy. H. pylori stool antigen (HpSA) and serum pepsinogen (PG) tests are useful tools for screening present infection and gastric atrophy, respectively. To ...

journal_title：Gut and liver

authors： Yamaoka M,Nakajima S

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND/AIMS:To determine factors predictive of discordance in staging liver fibrosis using liver biopsy (LB) and acoustic radiation force impulse (ARFI) elastography in patients with chronic hepatitis B (CHB). METHODS:Consecutive patients with CHB who underwent LB and ARFI elastography on the same day from Novembe...

journal_title：Gut and liver

authors： Park MS,Kim SW,Yoon KT,Kim SU,Park SY,Tak WY,Kweon YO,Cho M,Kim BK,Park JY,Kim DY,Ahn SH,Han KH

更新日期：2016-03-01 00:00:00

abstract：:It is known that neutropenia caused by combination pegylated interferon plus ribavirin therapy for hepatitis C virus (HCV) infection is well tolerated and carries a negligible risk of infection. Neutropenic enterocolitis is encountered most frequently in patients with hemato-oncologic diseases who are undergoing inten...

journal_title：Gut and liver

authors： Kim JH,Jang JW,You CR,You SY,Jung MK,Jung JH

更新日期：2009-09-01 00:00:00