Abstract：
PURPOSE:To review the fundamental principles of susceptibility-weighted imaging (SWI) and quantitative susceptibility mapping (QSM), and to discuss recent clinical developments. METHODS:SWI is a magnetic resonance imaging method that takes advantage of magnitude signal loss and phase information to reveal anatomic and physiologic information about tissue and venous vasculature. The method enhances image contrast qualitatively, relying on phase shifts due to differences in magnetic susceptibility between tissues. QSM, extending SWI in an elegant way, is a new sophisticated postprocessing technique that numerically solves the inverse source-effect problem to derive local tissue magnetic susceptibility (source) from the measured magnetic field distribution (effect) as it is reflected in the phase images of gradient-echo sequences. RESULTS:SWI has meanwhile been established in numerous clinical as well as basic biomedical applications due to its ability to highlight tissue structures and compounds that are difficult to detect by conventional magnetic resonance imaging (MRI), including iron, calcifications, small veins, blood, and bones. The field of QSM has also progressed rapidly, both in terms of optimizing the post-processing strategies and algorithms as well as in gaining ground for new clinical applications that take advantage of its quantitative nature and improved specificity to identify the magnetic signature of lesions. CONCLUSIONS:Though magnetic susceptibility may be a major nuisance producing image artifacts in MRI, recent work has transformed it into a useful source of image contrast. Both SWI and QSM are gaining increasing acceptance in clinical practice. In particular, QSM provides new insights into tissue composition and organization due to its more direct relation to the actual physical tissue magnetic properties.
journal_name
Clin Neuroradioljournal_title
Clinical neuroradiologyauthors
Reichenbach JR,Schweser F,Serres B,Deistung Adoi
10.1007/s00062-015-0432-9subject
Has Abstractpub_date
2015-10-01 00:00:00pages
225-30eissn
1869-1439issn
1869-1447pii
10.1007/s00062-015-0432-9journal_volume
25 Suppl 2pub_type
杂志文章,评审abstract：BACKGROUND:Temporary balloon test occlusion (BTO) might be performed prior to procedures in which occlusion of the internal carotid artery (ICA) might be necessary. We tested the hypothesis that parametric color coding (PCC) of angiographic series (digital subtraction angiography (DSA)) along with the assessment of cer...
journal_title：Clinical neuroradiology
pub_type： 临床试验,杂志文章
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更新日期：2013-12-01 00:00:00
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journal_title：Clinical neuroradiology
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journal_title：Clinical neuroradiology
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journal_title：Clinical neuroradiology
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journal_title：Clinical neuroradiology
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journal_title：Clinical neuroradiology
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journal_title：Clinical neuroradiology
pub_type： 杂志文章,评审
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更新日期：2014-12-01 00:00:00
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journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-017-0575-y
更新日期：2018-09-01 00:00:00
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journal_title：Clinical neuroradiology
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更新日期：2016-09-01 00:00:00
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更新日期：2013-06-01 00:00:00
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journal_title：Clinical neuroradiology
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journal_title：Clinical neuroradiology
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journal_title：Clinical neuroradiology
pub_type： 杂志文章,评审
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更新日期：2015-10-01 00:00:00
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journal_title：Clinical neuroradiology
pub_type： 杂志文章
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更新日期：2010-06-01 00:00:00
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journal_title：Clinical neuroradiology
pub_type： 杂志文章
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journal_title：Clinical neuroradiology
pub_type： 杂志文章
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更新日期：2019-03-01 00:00:00
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