Increased sign-tracking behavior in adolescent rats.

Abstract:

:An autoshaping procedure was used to test the notion that conditioned stimuli (CSs) gain greater incentive salience during adolescence than young adulthood under conditions of social isolation rearing and food restriction. Rats were single-housed and placed on food restriction during 10 daily training sessions in which a lever (CS+ ) was presented then followed immediately by a food unconditioned stimulus (US). A second lever (CS- ) was presented on intermixed trials and was not reinforced. Despite the fact that food delivery was not contingent on the rats' behavior, all rats exhibited behaviors directed towards the lever (i.e., sign-tracking). In the adolescent group, the rate of lever pressing and the percentage of trials with a lever press were higher than in young adults. Initially, group differences were observed when rats were retrained when the adolescents had reached young adulthood. These findings support the hypothesis that cues that come to predict reward become imbued with excessive motivational value in adolescents, perhaps contributing to the hyper-responsiveness to reward-related stimuli typically observed during this period of development.

journal_name

Dev Psychobiol

authors

DeAngeli NE,Miller SB,Meyer HC,Bucci DJ

doi

10.1002/dev.21548

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

840-847

issue

7

eissn

0012-1630

issn

1098-2302

journal_volume

59

pub_type

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