Acute toxicity of binary-metal mixtures of copper, zinc, and nickel to Pimephales promelas: Evidence of more-than-additive effect.

Abstract:

:Metal mixture toxicity has been studied for decades. However, the results are not consistent, and thus ecological risk assessment and regulation of mixtures has been difficult. The objective of the present study was to use a systematic experimental design to characterize the toxicity of binary-metal mixture of Cu, Zn, and Ni to Pimephales promelas, typically to determine whether the effect of these binary-metal mixtures on P. promelas is more-than-additive. Standard 96-h toxicity tests were conducted with larval P. promelas based on US Environmental and Protection Agency methods to determine metal mixture effects. All experiments were conducted in synthetic moderately hard water with no addition of dissolved organic matter. Three different effect analysis approaches, the MixTox model, the Finney model, and the toxic unit method, were used for comparison. The results indicate that the toxicity of Cu+Zn, Cu+Ni, and Zn+Ni mixtures to P. promelas was more-than-additive. Among the 3 mixtures, the effect of the Cu+Ni mixture was the most profound. The results of the present study are useful for applications to models such as the metal mixture biotic ligand model. More research should be conducted to determine the mechanisms of acute and chronic toxicity of metal mixtures.

journal_name

Environ Toxicol Chem

authors

Lynch NR,Hoang TC,O'Brien TE

doi

10.1002/etc.3204

subject

Has Abstract

pub_date

2016-02-01 00:00:00

pages

446-57

issue

2

eissn

0730-7268

issn

1552-8618

journal_volume

35

pub_type

杂志文章
  • Predicting ready biodegradability of premanufacture notice chemicals.

    abstract::Chemical substances other than pesticides, drugs, and food additives are regulated by the U.S. Environmental Protection Agency (U.S. EPA) under the Toxic Substances Control Act (TSCA), but the United States does not require that new substances be tested automatically for such critical properties as biodegradability. T...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:

    authors: Boethling RS,Lynch DG,Thom GC

    更新日期:2003-04-01 00:00:00

  • Acute-to-chronic species sensitivity distribution extrapolation.

    abstract::Seeking to make greater use of available data for risk assessment of substances, we constructed, for the situation in which chronic data are limited or even nonexistent but acute data are relatively large, an acute to chronic transformation (ACT) methodology based on the concept of species sensitivity distributions (S...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:

    authors: Duboudin C,Ciffroy P,Magaud H

    更新日期:2004-07-01 00:00:00

  • Potentiation of the vitellogenic response to 17alpha-ethinylestradiol by cortisol in the fathead minnow Pimephales promelas.

    abstract::The effects of elevated plasma cortisol levels on vitellogenin (VTG) induction were examined in the fathead minnow (Pimephales promelas) in an attempt to evaluate the potential influence of stress on this commonly used biomarker of estrogenicity. Two separate experiments were conducted in which fish plasma cortisol wa...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/04-309r.1

    authors: Brodeur JC,Woodburn KB,Klecka GM

    更新日期:2005-05-01 00:00:00

  • Species-specific metabolism of naphthalene and phenanthrene in 3 species of marine teleosts exposed to Deepwater Horizon crude oil.

    abstract::The 2 most abundant polycyclic aromatic hydrocarbons (PAHs) measured in Deepwater Horizon crude oil, naphthalene and phenanthrene, and their associated homologs have both been shown to be acutely toxic in fish. Although fish have a relatively high metabolic capacity for PAHs, hydroxylated PAH (OH-PAH) derivatives form...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3898

    authors: Pulster EL,Main K,Wetzel D,Murawski S

    更新日期:2017-11-01 00:00:00

  • Occurrence and mass loadings of n-alkanes in riverine runoff of the Pearl River Delta, South China: global implications for levels and inputs.

    abstract::Riverine runoff samples were collected monthly from March 2005 to February 2006 from the eight major outlets of the Pearl River Delta (PRD), South China, and analyzed to obtain the concentrations of n-alkanes in both the filtrate and particulate phases. The average concentrations of Sigma(C15-C34) (i.e., sum of C15 to...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/08-034.1

    authors: Wang JZ,Ni HG,Guan YF,Zeng EY

    更新日期:2008-10-01 00:00:00

  • Chronic toxicity of binary-metal mixtures of cadmium and zinc to Daphnia magna.

    abstract::The present study characterized the chronic effect of binary-metal mixtures of cadmium (Cd) and zinc (Zn) on Daphnia magna. The titration design was chosen to characterize the 21-d chronic effects of the binary-metal mixtures on survival, growth, reproduction, and metal accumulation in D. magna. Using this design, inc...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3830

    authors: Pérez E,Hoang TC

    更新日期:2017-10-01 00:00:00

  • Ecotoxicological assessment of glyphosate-based herbicides: Effects on different organisms.

    abstract::Glyphosate-based herbicides are the most commonly used worldwide because they are effective and relatively nontoxic to nontarget species. Unlimited and uncontrolled use of such pesticides can have serious consequences for human health and ecological balance. The present study evaluated the acute toxicity and genotoxic...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3580

    authors: de Brito Rodrigues L,de Oliveira R,Abe FR,Brito LB,Moura DS,Valadares MC,Grisolia CK,de Oliveira DP,de Oliveira GAR

    更新日期:2017-07-01 00:00:00

  • The toxicity of different lead salts to Enchytraeus crypticus in relation to bioavailability in soil.

    abstract::The present study aimed to assess the bioavailability and toxicity of lead nitrate and lead chloride to Enchytraeus crypticus in a natural standard soil. Worms were exposed to Pb-spiked soil for 21 d, and survival and reproduction were related to total, 0.01 M CaCl2 -extractable, and porewater Pb concentrations in the...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3738

    authors: Zhang L,Van Gestel CAM

    更新日期:2017-08-01 00:00:00

  • Toxicity of extracts from municipal wastewater to early life stages of Japanese medaka (Oryzias latipes) to evaluate removals of micropollutants by wastewater treatment.

    abstract::Treatment of municipal wastewater reduces the concentrations of some pharmaceuticals and personal care products (PPCPs), hormones, and drugs of abuse. However, reduced concentrations of these micropollutants in wastewater may not correlate with reduced toxicity because transformations of micropollutants and/or the for...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3939

    authors: Maya N,Crispo C,McFarland V,Nasuhoglu D,Isazadeh S,Yargeau V,Metcalfe CD

    更新日期:2018-01-01 00:00:00

  • Assessment of the estrogenicity and toxicity of a domestic wastewater effluent flowing through a constructed wetland system using biomarkers in male fathead minnows (Pimephales promelas rafinesque, 1820).

    abstract::The toxicity and estrogenicity of a final treated municipal effluent was examined while flowing through a constructed wetland in north-central Texas, USA. Fish data were collected, and a baseline wetland characterization was performed to assess wetland treatment potential for these effluent properties. Vitellogenin (V...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/1551-5028(2001)020<2268:aoteat>2.0.co;2

    authors: Hemming JM,Waller WT,Chow MC,Denslow ND,Venables B

    更新日期:2001-10-01 00:00:00

  • A benchmarking method to measure dietary absorption efficiency of chemicals by fish.

    abstract::Understanding the dietary absorption efficiency of chemicals in the gastrointestinal tract of fish is important from both a scientific and a regulatory point of view. However, reported fish absorption efficiencies for well-studied chemicals are highly variable. In the present study, the authors developed and exploited...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.2361

    authors: Xiao R,Adolfsson-Erici M,Åkerman G,McLachlan MS,MacLeod M

    更新日期:2013-12-01 00:00:00

  • Influence of sorbate planarity on the magnitude of rapidly desorbing fractions of organic compounds in sediment.

    abstract::Organic compounds in sediments are known to distribute between rapid, slowly, and very slowly desorbing sites. This distribution is relevant to bioavailability and risk assessment of organic compounds in sediment. In this study, the fraction desorbing to Tenax in 6 h was measured for a range of organic compounds in se...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:

    authors: van Noort PC,Cornelissen G,ten HT,Belfoid A

    更新日期:2002-11-01 00:00:00

  • Effects of carbaryl on green frog (Rana clamitans) tadpoles: timing of exposure versus multiple exposures.

    abstract::The majority of studies on pesticide impacts have evaluated the effects of single exposures. However, multiple exposures to a pesticide may be more prevalent. The objective of our study was to determine how multiple exposures versus single exposure at different times during development affected survival to metamorphos...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/02-401

    authors: Boone MD,Bridges CM

    更新日期:2003-11-01 00:00:00

  • Effects of silver nanoparticles on zebrafish (Danio rerio) and Escherichia coli (ATCC 25922): a comparison of toxicity based on total surface area versus mass concentration of particles in a model eukaryotic and prokaryotic system.

    abstract::Silver nanoparticles (Ag NPs) have been classified as the most abundant NP found in commercial products. In the present study, zebrafish (Danio rerio) and bacteria (Escherichia coli; ATCC 25922) were used to test the size-dependent toxicological effects of Ag NPs, the effects of ionic silver versus Ag NPs, and Ag NP e...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.1881

    authors: Bowman CR,Bailey FC,Elrod-Erickson M,Neigh AM,Otter RR

    更新日期:2012-08-01 00:00:00

  • Passive air sampling of polycyclic aromatic hydrocarbons and polychlorinated naphthalenes across Europe.

    abstract::This study presents concurrently sampled ambient air data for a range of polycyclic aromatic hydrocarbons (PAHs) and polychlorinated naphthalenes (PCNs) at the continental scale. This was achieved with a passive air sampling system, by deploying polyurethane foam disks, which were prepared in one laboratory, sealed to...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/03-420

    authors: Jaward FM,Farrar NJ,Harner T,Sweetman AJ,Jones KC

    更新日期:2004-06-01 00:00:00

  • Insights into the development of fungal biomarkers for metal ecotoxicity assessment: case of Trametes versicolor exposed to copper.

    abstract::The relationship between the physiological state of fungi and the response of their functional system to metals is not known, limiting the use of fungal enzymes as tools for assessing metal ecotoxicity in terrestrial ecosystems. The present study attempts to establish how the development phases modulate the secretion ...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.101

    authors: Lebrun JD,Trinsoutrot-Gattin I,Laval K,Mougin C

    更新日期:2010-04-01 00:00:00

  • Influence of developmental stage on sensitivity to ammonium nitrate of aquatic stages of amphibians.

    abstract::In static renewal experiments, we studied how developmental stage influences the effect of ammonium nitrate on embryonic and larval stages of anuran amphibians. The observed lethal effects caused by ammonium nitrate increased with both concentration and duration of exposure. Significant differences were observed in se...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/05-023r.1

    authors: Ortiz-Santaliestra ME,Marco A,Fernández MJ,Lizana M

    更新日期:2006-01-01 00:00:00

  • Response predictions for organisms water-exposed to metal mixtures: a meta-analysis.

    abstract::To develop a multimetal toxicity model requires insight into the relationships between the composition of metal mixtures and their toxicological effects on organisms. As a first step in developing such a model, quantitative data from binary and higher mixture studies of Cu, Cd, and Zn were compiled and used to assess ...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章,meta分析

    doi:10.1002/etc.499

    authors: Vijver MG,Elliott EG,Peijnenburg WJ,de Snoo GR

    更新日期:2011-06-01 00:00:00

  • Metal distribution and metallothionein induction after cadmium exposure in the terrestrial snail Helix aspersa (Gastropoda, Pulmonata).

    abstract::The aim of the present work was to study the effect of Cd2+ exposure on metallothionein (MT) induction and on the distribution of metals (Cd, Cu, and Zn) in the terrestrial pulmonate Helix aspersa. In particular, the soluble and nonsoluble pools of the accumulated metals and their tissue distribution in uncontaminated...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/07-232.1

    authors: Hispard F,Schuler D,de Vaufleury A,Scheifler R,Badot PM,Dallinger R

    更新日期:2008-07-01 00:00:00

  • Determination of in situ polychlorinated biphenyl elimination rate coefficients in the freshwater mussel biomonitor Elliptio complanata deployed in the Huron-Erie corridor, southeast Michigan, USA, and southwest Ontario, Canada.

    abstract::Quantitative mussel biomonitoring studies often use laboratory-measured whole-body elimination rate coefficients (k(tot) in conjunction with concentration data from field-deployed mussels to estimate bioavailable steady-state contaminant concentrations (C(m(ss)) in aquatic systems. However, the validity of applying la...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/08-115.1

    authors: Raeside AA,O'Rourke SM,Drouillard KG

    更新日期:2009-02-01 00:00:00

  • Heavy metal-induced toxicity in the Indian green frog: Biochemical and histopathological alterations.

    abstract::Heavy metal contamination may have adverse effects on wetland biota, particularly on amphibians. Severe immunotoxic effects elicited in Euphlyctis hexadactylus (Indian green frog) because of metal exposure (Cd, Cr, Cu, Pb, and Zn) in the Bellanwila-Attidiya Sanctuary, a polluted urban wetland in Sri Lanka, provided th...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.3848

    authors: Jayawardena UA,Angunawela P,Wickramasinghe DD,Ratnasooriya WD,Udagama PV

    更新日期:2017-10-01 00:00:00

  • Accumulation and maternal transfer of polychlorinated biphenyls in snapping turtles of the upper Hudson River, New York, USA.

    abstract::We conducted field studies over three years to assess body burdens and maternal transfer of polychlorinated biphenyls (PCBs) as well as indices of sexual dimorphism in snapping turtles (Chelydra serpentina) of the upper Hudson River (NY, USA.) We collected adult turtles in areas known to be contaminated with PCBs and ...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/08-098.1

    authors: Kelly SM,Eisenreich KM,Baker JE,Rowe CL

    更新日期:2008-12-01 00:00:00

  • Assessing causation of the extirpation of stream macroinvertebrates by a mixture of ions.

    abstract::Increased ionic concentrations are associated with the impairment of benthic invertebrate assemblages. However, the causal nature of that relationship must be demonstrated so that it can be used to derive a benchmark for conductivity. The available evidence is organized in terms of six characteristics of causation: co...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.2059

    authors: Cormier SM,Suter GW 2nd,Zheng L,Pond GJ

    更新日期:2013-02-01 00:00:00

  • Changes in growth and secondary sex characteristics of fathead minnows exposed to bleached sulfite mill effluent.

    abstract::Yellow perch captured downstream of a bleached sulfite mill had reduced gonad size and fecundity, and circulating steroid levels declined in goldfish exposed to final effluent for 21 d. To assess bleached sulfite mill (BSM) effluent, long-term fathead minnow (Pimephales promelas) growth and reproduction tests were car...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/02-237

    authors: Parrott JL,Wood CS,Boutot P,Dunn S

    更新日期:2003-12-01 00:00:00

  • Implications of global climate change for the assessment and management of human health risks of chemicals in the natural environment.

    abstract::Global climate change (GCC) is likely to alter the degree of human exposure to pollutants and the response of human populations to these exposures, meaning that risks of pollutants could change in the future. The present study, therefore, explores how GCC might affect the different steps in the pathway from a chemical...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.2046

    authors: Balbus JM,Boxall AB,Fenske RA,McKone TE,Zeise L

    更新日期:2013-01-01 00:00:00

  • Assessment of Transcriptomic and Apical Responses of Daphnia magna Exposed to a Polyethylene Microplastic in a 21-d Chronic Study.

    abstract::There is global concern regarding the fate and effects of microplastics in the environment, particularly in aquatic systems. In the present study, ethylene acrylic acid copolymer particles were evaluated in a chronic toxicity study with the aquatic invertebrate Daphnia magna. The study design included a natural partic...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.4745

    authors: Coady KK,Burgoon L,Doskey C,Davis JW

    更新日期:2020-08-01 00:00:00

  • Bioassay of cadmium using a DNA microarray: genome-wide expression patterns of Saccharomyces cerevisiae response to cadmium.

    abstract::DNA microarray technology enables genome-wide detection of cell response at the transcriptional level. We are planning to make bioassay systems that can detect environmental chemicals to screen for potential bioreactive agents. To develop a DNA microarray for our purposes, the changes in gene expression underlying the...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/1551-5028(2001)020<2353:bocuad>2.0.co;2

    authors: Momose Y,Iwahashi H

    更新日期:2001-10-01 00:00:00

  • Accumulation and distribution of polychlorinated dibenzo-p-dioxin, dibenzofuran, and polychlorinated biphenyl congeners in Atlantic salmon (Salmo salar).

    abstract::Adult Atlantic salmon (Salmo salar) were fed on four diets containing polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) for 30 weeks. Lipid-normalized concentrations showed that all congeners were equally partitioned between whole-fish and fillet sam...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1897/03-367

    authors: Isosaari P,Kiviranta H,Lie O,Lundebye AK,Ritchie G,Vartiainen T

    更新日期:2004-07-01 00:00:00

  • Assessing the sublethal effects of in-river concentrations of parameters contributing to cumulative effects in the Athabasca river basin using a fathead minnow bioassay.

    abstract::The Athabasca River basin, located in Alberta, Canada, covers 157, 000 km(2) and holds significant cultural and economic importance. Recent research assessed changes in several water quality and quantity parameters that have changed both spatially (along the river continuum) and temporally (pre-development and present...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:10.1002/etc.2081

    authors: Squires AJ,Dubé MG,Rozon-Ramilo LD

    更新日期:2013-03-01 00:00:00

  • Toxicity evaluation of a commercial bioremediation agent mixed with crude oil.

    abstract::The toxicity and efficacy of a bacteria-based commercial bioremediation agent (CBA) was assessed through bioassays with juvenile inland silverside minnows, Menidia beryllina, and flask studies of oil degradation. Addition of the CBA to weathered Alaska, USA North Slope crude oil (ANS-521) prior to testing increased to...

    journal_title:Environmental toxicology and chemistry

    pub_type: 杂志文章

    doi:

    authors: Bidwell JR,Cherry DS,Merski AT

    更新日期:2003-01-01 00:00:00