Optic nerve blockade influences the retinal responses to flash in rabbits.

Abstract:

:The presence of retinopetal fibers in mammals has been debated many times in the past two decades. Do rabbits have a retinopetal system? This question is addressed with the present investigations. In anesthetized and paralysed rabbits the b-wave and the oscillatory potentials (OP) are recorded at the cornea. The optic nerve is isolated retrobulbarly and is gently hooked to a curved injecting capillary. Through the latter lidocaine hydrochloride is pressure injected. This drug interrupts the neuronal flow travelling along the nerve. A steel electrode is positioned in the optic chiasm allowing us to monitor the evoked field potentials from the tested and untested eyes. The optic nerve blockade produces the following observations: (1) the amplitude of the b-wave is not significantly altered; and (2) the amplitudes of the long latency OP are significantly increased. The retinal capacity to respond to a second flash after the application of an initial light pulse was evaluated by varying the interval between the two flashes. After optic nerve blockade the recovery of the retinal responsiveness is considerably slower. Fourier analysis indicated that the highest power increases occurred around 200 Hz. It is difficult to escape the suggestion that rabbits possess retinopetal fibers.

journal_name

Vision Res

journal_title

Vision research

authors

Molotchnikoff S,Lachapelle P,Casanova C

doi

10.1016/0042-6989(89)90110-7

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

957-63

issue

8

eissn

0042-6989

issn

1878-5646

pii

0042-6989(89)90110-7

journal_volume

29

pub_type

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