Epidural patch with autologous platelet rich plasma: a novel approach.

Abstract:

:We aimed to perform an epidural patch using platelet rich plasma (PRP), which has the potential to regenerate and heal tissues via degranulation of platelets, in a 34-year-old parturient suffering from persistent post-dural puncture headache (PDPH) after failed epidural blood patch (EBP). After her admission to our unit, we reconfirmed the clinical and radiologic diagnosis of PDPH. Cranial MRI with contrast showed diffuse pachymeningeal thickening and contrast enhancement with enlarged pituitary consistent with intracranial hypotension. Clinical and radiological improvements were observed 1 week after the epidural patch using autologous PRP. Therefore, we recommend using autologous PRP for epidural patching in patients with incomplete recovery after standard EBP as a novel successful approach.

journal_name

J Anesth

journal_title

Journal of anesthesia

authors

Gunaydin B,Acar M,Emmez G,Akcali D,Tokgoz N

doi

10.1007/s00540-017-2400-9

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

907-910

issue

6

eissn

0913-8668

issn

1438-8359

pii

10.1007/s00540-017-2400-9

journal_volume

31

pub_type

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