The association between psychosis and severe pain in community-dwelling adults: Findings from 44 low- and middle-income countries.

Abstract:

:Previous studies examining the association between schizophrenia and pain have produced mixed results and data on sub-threshold psychosis or psychotic symptoms and pain are scarce. This study assessed the association between psychosis and severe pain among community-dwelling adults in 44 low- and middle-income countries (LMICs) where no data exists. Data on 235,370 adults aged ≥18 years from the World Health Survey (WHS) 2002-2004 were analyzed. The presence of past 12-month psychotic symptoms was established using four questions from the Composite International Diagnostic Interview. Participants were categorized into four mutually exclusive groups based on whether they had at least one psychotic symptom and/or a lifetime psychosis or schizophrenia diagnosis. Multivariable logistic regression was used to estimate the association between psychosis and past 30-day severe pain. The prevalence of severe pain among those with 0, 1, 2, ≥3 psychotic symptoms was 8.7%, 16.7%, 21.8%, 30.5% respectively. Compared to those with no psychotic symptoms or diagnosis, the ORs (95% CIs) were: at least one symptom without diagnosis [2.17 (1.99-2.38)]; no symptom with diagnosis [2.33 (1.71-3.17)]; at least one symptom and diagnosis [4.27 (3.20-5.71)]. Associations were partly mediated by chronic physical conditions, anxiety, and depression. Despite some limitations such as the use of a single-item question to assess pain, the results of this study suggest that individuals with psychotic symptoms or a psychosis diagnosis should be systematically assessed for pain, and if necessary, receive treatment for pain and its underlying conditions. Future research on the effect of pain management on psychosis outcome is warranted.

journal_name

J Psychiatr Res

authors

Koyanagi A,Stickley A

doi

10.1016/j.jpsychires.2015.07.020

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

19-26

eissn

0022-3956

issn

1879-1379

pii

S0022-3956(15)00213-7

journal_volume

69

pub_type

杂志文章
  • Persistent mental health impacts of disaster. Five-year follow-up after the 2011 great east Japan earthquake and tsunami: Iwanuma Study.

    abstract::Few studies have tracked the long-term mental health outcomes following major disaster. We sought to document the trajectories of depressive symptoms and post-traumatic stress symptoms (PTSS) in the aftermath of the 2011 Great East Japan earthquake and tsunami. A cohort of community-dwelling older adults were followed...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2020.08.016

    authors: Kino S,Aida J,Kondo K,Kawachi I

    更新日期:2020-08-23 00:00:00

  • Illuminating the treatment gap of mental disorders: A comparison of community survey-based and national registry-based prevalence rates in Korea.

    abstract::Estimating the prevalence rates of mental disorders is important for developing prevention, treatment, and research plans. Given that survey-based and registry-based prevalence rates of mental disorders each have pros and cons yet complement one another, it is important to consider both assessments when investigating ...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2020.07.047

    authors: Jo M,Rim SJ,Lee MG,Park S

    更新日期:2020-11-01 00:00:00

  • The somatosensory amplification scale and its relationship to hypochondriasis.

    abstract::Forty-one DSM-III-R hypochondriacs and seventy-five randomly chosen patients were obtained from a medical outpatient clinic, and completed a psychiatric diagnostic interview and a ten-item self-report questionnaire, the Somatosensory Amplification Scale (SSAS); The SSAS asks the respondent how much s/he is bothered by...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/0022-3956(90)90004-a

    authors: Barsky AJ,Wyshak G,Klerman GL

    更新日期:1990-01-01 00:00:00

  • Frequency and correlates of anxiety symptoms during the COVID-19 pandemic in low- and middle-income countries: A multinational study.

    abstract:OBJECTIVE:Studies have documented the significant direct and indirect psychological, social, and economic consequences of the Coronavirus disease 2019 (COVID-19) in many countries but little is known on its impact in low- and middle-income countries (LMICs) already facing difficult living conditions and having vulnerab...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jpsychires.2020.09.031

    authors: Cénat JM,Dalexis RD,Guerrier M,Noorishad PG,Derivois D,Bukaka J,Birangui JP,Adansikou K,Clorméus LA,Kokou-Kpolou CK,Ndengeyingoma A,Sezibera V,Auguste RE,Rousseau C

    更新日期:2021-01-01 00:00:00

  • Neuroendocrine effects of benzodiazepines.

    abstract::Benzodiazepine administration has been associated with alterations in neuroendocrine function both in experimental animals and in humans. Clinical and laboratory data indicate that the beta-carbolines, a class of active benzodiazepine receptor inverse agonists, cause behavioral and neuroendocrine changes characteristi...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章,评审

    doi:10.1016/0022-3956(90)90042-o

    authors: De Souza EB

    更新日期:1990-01-01 00:00:00

  • Markers in psychoses: studies from India.

    abstract::Genetic considerations are important in studying the pathogenesis of the psychoses. There are few reports from India, however, which have pursued a "biological marker" approach to functional illness of this type. A review of such few studies as do exist is presented to add to contemporary knowledge in the area. Recomm...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章,评审

    doi:10.1016/0022-3956(84)90026-8

    authors: Sethi BB,Dube S,Sharma M

    更新日期:1984-01-01 00:00:00

  • Frequency of bulimic behaviors and associated social maladjustment in female graduate students.

    abstract::A questionnaire survey of 550 female medical, business and law students revealed that 12% met criteria for bulimia. The bulimic students reported significantly more social maladjustment than their non-eating disordered peers. Frequency of binging and purging was associated with the degree of social impairment, with si...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/0022-3956(86)90038-5

    authors: Herzog DB,Norman DK,Rigotti NA,Pepose M

    更新日期:1986-01-01 00:00:00

  • The role and interpretation of pilot studies in clinical research.

    abstract::Pilot studies represent a fundamental phase of the research process. The purpose of conducting a pilot study is to examine the feasibility of an approach that is intended to be used in a larger scale study. The roles and limitations of pilot studies are described here using a clinical trial as an example. A pilot stud...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2010.10.008

    authors: Leon AC,Davis LL,Kraemer HC

    更新日期:2011-05-01 00:00:00

  • Metabolic decoupling in daily life in patients with panic disorder and agoraphobia.

    abstract::Various studies have assessed autonomic and respiratory underpinnings of panic attacks, yet the psychophysiological functioning of panic disorder (PD) patients has rarely been examined under naturalistic conditions at times when acute attacks were not reported. We hypothesized that emotional activation in daily life c...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2015.04.027

    authors: Pfaltz MC,Kolodyazhniy V,Blechert J,Margraf J,Grossman P,Wilhelm FH

    更新日期:2015-09-01 00:00:00

  • Sex differences in response to ketamine as a rapidly acting intervention for treatment resistant depression.

    abstract:BACKGROUND:While ketamine has been increasingly studied for treatment resistant depression (TRD), the impact of sex differences on treatment outcomes has not been well studied. The objective was to ascertain whether there were differences in response to a single administration of ketamine for TRD between men and women,...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jpsychires.2019.01.010

    authors: Freeman MP,Papakostas GI,Hoeppner B,Mazzone E,Judge H,Cusin C,Mathew S,Sanacora G,Iosifescu D,DeBattista C,Trivedi MH,Fava M

    更新日期:2019-03-01 00:00:00

  • A comparison between self-report and interviewer-rated retrospective reports of childhood abuse among individuals with first-episode psychosis and population-based controls.

    abstract::The typical reliance on self-report questionnaires in retrospective case-control studies of childhood abuse and psychotic disorders has been criticised, due to the potential for recall bias associated with, amongst other factors, cognitive impairments and detachment from reality, among individuals with psychosis. One ...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2020.02.002

    authors: Gayer-Anderson C,Reininghaus U,Paetzold I,Hubbard K,Beards S,Mondelli V,Di Forti M,Murray RM,Pariante CM,Dazzan P,Craig TJ,Fisher HL,Morgan C

    更新日期:2020-04-01 00:00:00

  • Prevalence of psychiatric morbidity and psychological adaptation of the nurses in a structured SARS caring unit during outbreak: a prospective and periodic assessment study in Taiwan.

    abstract::To assess the rapidly changing psychological status of nurses during the acute phase of the 2003 SARS outbreak, we conducted a prospective and periodic evaluation of psychiatric morbidity and psychological adaptation among nurses in SARS units and non-SARS units. Nurse participants were from two SARS units (regular SA...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2005.12.006

    authors: Su TP,Lien TC,Yang CY,Su YL,Wang JH,Tsai SL,Yin JC

    更新日期:2007-01-01 00:00:00

  • The distribution and morphology of prefrontal cortex pyramidal neurons identified using anti-neurofilament antibodies SMI32, N200 and FNP7. Normative data and a comparison in subjects with schizophrenia, bipolar disorder or major depression.

    abstract::Alterations in the density and size of pyramidal neurons in the prefrontal cortex have been described in schizophrenia and mood disorder. However, the changes are generally modest and have not always been replicated. We investigated the possibility that specific pyramidal neuron sub-populations, defined by their immun...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/s0022-3956(03)00075-x

    authors: Law AJ,Harrison PJ

    更新日期:2003-11-01 00:00:00

  • Zolpidem and the risk of Parkinson's disease: a nationwide population-based study.

    abstract:BACKGROUND:This nationwide population-based study investigated the risk of Parkinson's disease (PD) after zolpidem use in patients with sleep disturbance using the National Health Insurance Research Database (NHIRD) in Taiwan. MATERIAL AND METHODS:In total, 59,548 adult patients newly diagnosed with sleep disturbance ...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2014.07.003

    authors: Yang YW,Hsieh TF,Yu CH,Huang YS,Lee CC,Tsai TH

    更新日期:2014-11-01 00:00:00

  • Cigarette smoking in Chinese male inpatients with schizophrenia: a cross-sectional analysis.

    abstract::Given the high rates of cigarette smoking in schizophrenia in many published studies from around the world, we studied the relationship between smoking status and clinical characteristics in male Chinese schizophrenic inpatients. Two hundred seventy-nine schizophrenic inpatients were assessed using clinical data forms...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2005.10.009

    authors: Tang YL,George TP,Mao PX,Cai ZJ,Chen Q

    更新日期:2007-01-01 00:00:00

  • Trajectories of suicidal ideation in depressed older adults undergoing antidepressant treatment.

    abstract:UNLABELLED:Suicide is a public health concern in older adults. Recent cross sectional studies suggest that impairments in executive functioning, memory and attention are associated with suicidal ideation in older adults. It is unknown whether these neuropsychological features predict persistent suicidal ideation. We an...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2015.11.004

    authors: Kasckow J,Youk A,Anderson SJ,Dew MA,Butters MA,Marron MM,Begley AE,Szanto K,Dombrovski AY,Mulsant BH,Lenze EJ,Reynolds CF 3rd

    更新日期:2016-02-01 00:00:00

  • Vitamin A supplementation at clinical doses induces a dysfunction in the redox and bioenergetics states, but did change neither caspases activities nor TNF-alpha levels in the frontal cortex of adult Wistar rats.

    abstract::Vitamin A and its derivatives, the retinoids, exert modulatory roles on central nervous system (CNS) function. However, the clinical use of vitamin A at moderate to high doses induces serious side effects, including dysfunctional brain metabolism and mood disorders. Then, we have investigated in this work the effects ...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2008.10.002

    authors: De Oliveira MR,Oliveira MW,Behr GA,Moreira JC

    更新日期:2009-05-01 00:00:00

  • Dietary intake and plasma metabolomic analysis of polyunsaturated fatty acids in bipolar subjects reveal dysregulation of linoleic acid metabolism.

    abstract::Polyunsaturated fatty acids (PUFA) profiles associate with risk for mood disorders. This poses the hypothesis of metabolic differences between patients and unaffected healthy controls that relate to the primary illness or are secondary to medication use or dietary intake. However, dietary manipulation or supplementati...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2014.06.001

    authors: Evans SJ,Ringrose RN,Harrington GJ,Mancuso P,Burant CF,McInnis MG

    更新日期:2014-10-01 00:00:00

  • A summary of attentional findings in the New York High-Risk Project.

    abstract::We summarize here our findings with respect to attentional impairment among offspring of schizophrenic, affectively ill, and normal parents followed from childhood to adulthood during the two decades of the New York High-Risk Project (NYHRP). We review our data first, on childhood attentional performance in each of ou...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/0022-3956(92)90043-n

    authors: Erlenmeyer-Kimling L,Cornblatt BA

    更新日期:1992-10-01 00:00:00

  • Age at onset in bipolar-related major affective illness: clinical and genetic implications.

    abstract::Age-of-onset data were collected on 142 bipolar probands (61 males, 81 females) and 110 siblings. After correcting for demographic factors the age at illness onset did not distinguish bipolar from unipolar siblings or siblings from probands. This indicates that in a subset of pedigree data, bipolar and unipolar affect...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/0022-3956(82)90030-9

    authors: Baron M,Risch N,Mendlewicz J

    更新日期:1982-01-01 00:00:00

  • Increased lipid peroxidation and neuron specific enolase in treatment refractory schizophrenics.

    abstract::It is well-known that increased lipid peroxidation and failure of antioxidant mechanisms leads to neuronal damage in schizophrenic patients. However, this neurodegenerative mechanism has not been studied in treatment refractory schizophrenics (TRS). Therefore, the main purpose of this study was to determine neuronal d...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2006.02.010

    authors: Medina-Hernández V,Ramos-Loyo J,Luquin S,Sánchez LF,García-Estrada J,Navarro-Ruiz A

    更新日期:2007-10-01 00:00:00

  • Affective disorders and ABO blood groups: new data and a reanalysis of the literature using the logistic transformation of proportions.

    abstract::No statistically significant associations were found between ABO blood group distributions and RDC subtype diagnoses in 79 subjects with unipolar (single episode and recurrent) and bipolar major depressive disorder using data from our sample. We discuss methodological issues related to the control samples and choice o...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/0022-3956(84)90003-7

    authors: Lavori PW,Keller MB,Roth SL

    更新日期:1984-01-01 00:00:00

  • Narcissistic Personality Disorder and suicidal behavior in mood disorders.

    abstract::The relationship of Narcissistic Personality Disorder (NPD) to suicidal behavior is understudied. The modest body of existing research suggests that NPD is protective against low-lethality suicide attempts, but is associated with high lethality attempts. Mood-disordered patients (N = 657) received structured interview...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2016.10.020

    authors: Coleman D,Lawrence R,Parekh A,Galfalvy H,Blasco-Fontecilla H,Brent DA,Mann JJ,Baca-Garcia E,Oquendo MA

    更新日期:2017-02-01 00:00:00

  • Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia.

    abstract::Schizophrenia (SCZ) is the result of DNA alterations and environmental factors, which together lead to differential protein expression and ultimately to the development of the illness. The diagnosis is based on clinical symptoms, and the molecular background of SCZ is not completely understood. The thalamus, whose dys...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2010.04.014

    authors: Martins-de-Souza D,Maccarrone G,Wobrock T,Zerr I,Gormanns P,Reckow S,Falkai P,Schmitt A,Turck CW

    更新日期:2010-12-01 00:00:00

  • Selective anterior cingulate cortex deficit during conflict solution in schizophrenia: an event-related potential study.

    abstract:BACKGROUND:Schizophrenia research has gained a new focus on identification and further characterization of neurocognitive deficits in the search for behavioural endophenotypes of this disorder. The objective of this study was to explore differential cortical processing during executive control in schizophrenia as asses...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2006.06.012

    authors: Neuhaus AH,Koehler S,Opgen-Rhein C,Urbanek C,Hahn E,Dettling M

    更新日期:2007-10-01 00:00:00

  • Cortical midline structures associated with rumination in women with PTSD.

    abstract::Elevated rumination, characterized by repetitive, negative self-focused cognition, is common in posttraumatic stress disorder (PTSD) and has been shown to predict the onset and maintenance of the disorder. Neuroimaging research has implicated cortical midline brain structures, including the rostral anterior cingulate ...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2020.09.001

    authors: Philippi CL,Pessin S,Reyna L,Floyd T,Bruce SE

    更新日期:2020-12-01 00:00:00

  • Fatty acid composition in the postmortem amygdala of patients with schizophrenia, bipolar disorder, and major depressive disorder.

    abstract::Previous studies with postmortem brain tissues showed abnormalities in n-3 polyunsaturated fatty acids (PUFAs) in the orbitofrontal cortex of individuals with schizophrenia and mood disorders. However, in the hippocampus, we were not able to find any significant differences in PUFAs except for small differences in n-6...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2012.04.012

    authors: Hamazaki K,Hamazaki T,Inadera H

    更新日期:2012-08-01 00:00:00

  • Effect of male-specific childhood trauma on telomere length.

    abstract::Child maltreatment (CM) is a global issue with serious lifelong consequences. In fact, maltreatment during childhood might be an important risk factor for the development of psychiatric disorders. Furthermore, previous studies showed a strong relationship between telomere length (TL) and early life stress. Considering...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2018.10.012

    authors: Xavier G,Spindola LM,Ota VK,Carvalho CM,Maurya PK,Tempaku PF,Moretti PN,Mazotti DR,Sato JR,Brietzke E,Miguel EC,Grassi-Oliveira R,Mari J,Bressan RA,Gadelha A,Pan PM,Belangero SI

    更新日期:2018-12-01 00:00:00

  • Decoding rumination: A machine learning approach to a transdiagnostic sample of outpatients with anxiety, mood and psychotic disorders.

    abstract:OBJECTIVE:To employ machine learning algorithms to examine patterns of rumination from RDoC perspective and to determine which variables predict high levels of maladaptive rumination across a transdiagnostic sample. METHOD:Sample of 200 consecutive, consenting outpatient referrals with clinical diagnoses of schizophre...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2019.12.005

    authors: Silveira ÉM Júnior,Passos IC,Scott J,Bristot G,Scotton E,Teixeira Mendes LS,Umpierre Knackfuss AC,Gerchmann L,Fijtman A,Trasel AR,Salum GA,Kauer-Sant'Anna M

    更新日期:2020-02-01 00:00:00

  • Psychopathology factors in first-episode affective and non-affective psychotic disorders.

    abstract:BACKGROUND:Since the onset, prevalence, and course of specific psychopathological features rarely have been analyzed simultaneously from the start of dissimilar psychotic illnesses, we compared symptom-clusters in first-episode DSM-IV affective and non-affective psychotic disorders. METHODS:Subjects (N=377) from the M...

    journal_title:Journal of psychiatric research

    pub_type: 杂志文章

    doi:10.1016/j.jpsychires.2006.04.008

    authors: Salvatore P,Khalsa HM,Hennen J,Tohen M,Yurgelun-Todd D,Casolari F,Depanfilis C,Maggini C,Baldessarini RJ

    更新日期:2007-11-01 00:00:00