Abstract:
:B-cell lymphomas represent approximately 20% to 25% of primary cutaneous lymphomas. Within this group, most cases (>99%) are encompassed by 3 diagnostic entities: primary cutaneous marginal zone lymphoma, primary cutaneous follicle center lymphoma, and primary cutaneous diffuse large B-cell lymphoma, leg type. In this article, the authors present clinical, histopathologic, immunophenotypic, and molecular features of each of these entities and briefly discuss the rarer intravascular large B-cell lymphoma.
journal_name
Clin Lab Medjournal_title
Clinics in laboratory medicineauthors
Hope CB,Pincus LBdoi
10.1016/j.cll.2017.05.009subject
Has Abstractpub_date
2017-09-01 00:00:00pages
547-574issue
3eissn
0272-2712issn
1557-9832pii
S0272-2712(17)30045-8journal_volume
37pub_type
杂志文章,评审abstract::Pet guinea pigs are presented to veterinary clinics for routine care and treatment of clinical diseases. In addition to obtaining clinical history and exam findings, diagnostic testing may be required, including hematological assessments. This article describes common blood collection methods, including venipuncture s...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2015.05.012
更新日期:2015-09-01 00:00:00
abstract::The authors describe a system for collecting usage metrics from widely distributed automation systems. An application that records and stores usage data centrally, calculates run times, and charts the data was developed. Data were collected over 20 months from at least 28 workstations. The application was used to plot...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章
doi:10.1016/j.cll.2006.12.001
更新日期:2007-03-01 00:00:00
abstract::Automated image processing analysis for leukocyte differential counting started 30 years ago principally as a mimic of the traditional microscopic method. Several types of systems were used in the 1970s and 1980s. In the late 1990s, two new image processing systems were developed with new technology for cell image ana...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/s0272-2712(03)00076-3
更新日期:2002-03-01 00:00:00
abstract::Vitamin D has been associated with many health conditions. Because of widespread deficiency in the general population, laboratory testing of vitamin D has increased exponentially in recent years. Currently, 25-hydroxyvitamin D (25[OH]D) is considered the best marker of vitamin D status. Automated immunoassays and tand...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2018.05.007
更新日期:2018-09-01 00:00:00
abstract::Technical advances in laboratory testing such as sensitive chemical tests and standardized commercial slides have significantly altered our entire approach to urinalysis. In addition, the recognition of the association of microhematuria with urologic neoplasms and the morphologically altered red blood cells with renal...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1985-06-01 00:00:00
abstract::This article describes a method for evaluating some of the medical, economic, and personal consequences of different policies of monitoring patients for various disorders. The problem is difficult because it is dynamic. Most conditions develop over time, and in many cases the sensitivity of the test as well as the cos...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1982-12-01 00:00:00
abstract::Variation in the genome of hepatitis B virus has been associated with a number of clinical parameters, but there is a paucity of functional data to show a causal relationship. For example, variants of the core and X genes have been linked with the pathogenesis of chronic hepatitis, viral replication efficiency, and se...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1996-06-01 00:00:00
abstract::This article has presented information concerning the ultrastructural features and, to a lesser degree, the immunohistochemical characteristics of lung neoplasms. Electron microscopy and immunohistochemistry are useful techniques for diagnosing and understanding common and rare lung tumors. Electron microscopy is part...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract::There is growing evidence supporting the genetic variability outside of HLA system that is contributing to the variation in transplant outcomes. Determining novel predictors could help to identify patients at risk and tailor their immunosuppressive regimens. This article discusses the various single nucleotide polymor...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2018.10.002
更新日期:2019-03-01 00:00:00
abstract::A decision model was developed to evaluate the costs and benefits of further reducing the risk of transfusion-transmitted disease. The model addresses recipient risk factors as well as operational considerations. Application of the model to prior risk reduction decisions documents its validity as a decision-making too...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::To date, CRP remains the single standard biochemical marker for predicting the severity of AP. Because the combination of clinico-physiological scores and CRP provides good information at 48 hours, research has focused on the predictive ability of various markers when applied in the initial 24 hours after admission to...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2004.12.003
更新日期:2005-03-01 00:00:00
abstract::Advances in molecular genetics have had a major impact on our understanding of the pathogenesis of neurologic disorders. This article discusses molecular genetic contributions to our knowledge of Huntington's disease, amyotrophic lateral sclerosis, and Alzheimer's disease, as well as their implications for diagnosis a...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1995-12-01 00:00:00
abstract::Contemporary bacterial serology relevant to medicine involves poly- and monoclonal antibodies to study pathogenic bacteria and nonpathogenic organisms useful in controlling infectious diseases. Monoclonal antibody applications include immunodiagnostics, prophylaxis and serotherapy, and microbial biotechnology and mole...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1985-09-01 00:00:00
abstract::Neonatal alloimmune thrombocytopenia (NAIT) is the most common cause of severe thrombocytopenia in the healthy newborn, occurring in 1 in 1000 live births. NAIT is analogous to rhesus alloimmunization in pathophysiology; however, it often presents unexpectedly in first pregnancies. Presentation of NAIT varies from mil...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2013.03.024
更新日期:2013-06-01 00:00:00
abstract::This study examines the relationship between D-dimer concentration and patient age, gender, race, and renal function, and the role of D-dimer concentration as a predictor of in-hospital mortality, in a critically ill patient population. The results demonstrate there is a correlation between increased D-dimer concentra...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2014.06.015
更新日期:2014-09-01 00:00:00
abstract::Diabetes mellitus affects almost 16 million Americans. It has become a major public health problem and the number one cause of adult blindness, end-stage renal disease, and nontraumatic amputations in the United States. It also markedly increases the risk for cardiovascular, cerebrovascular, and peripheral artery dise...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:2001-03-01 00:00:00
abstract::This article reviews congenital melanocytic nevi (CMN), which are present at birth or appear shortly thereafter, and their main histologic features. Several histologic variants and histopathologic criteria that differentiate CMN from other nevi, such as atypical or dysplastic nevi, and from nevoid malignant melanoma, ...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2011.03.004
更新日期:2011-06-01 00:00:00
abstract::Market forces and service demands are driving a segment of laboratory testing away from centralized laboratories and closer to the patient's bedside. Placed into a historical perspective, this should be neither surprising nor distressing. Terminology is being clarified and professional societies are beginning to take ...
journal_title:Clinics in laboratory medicine
pub_type: 历史文章,杂志文章,评审
doi:
更新日期:1994-09-01 00:00:00
abstract::I have reviewed many of the methods available for the assessment of fetal lung maturity. The difficulty of using diagnostic tests for diseases of low prevalence has been discussed. By reviewing the nature of the amniotic fluid surfactant material, and some of the principles underlying analytical methods, the bases of ...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract::The development of antimicrobic susceptibility testing is outlined with particular reference to standardization of procedures and organizational developments that have led to substantially improved performance. Special problems continue to be posed by increased proportions of opportunistic pathogens and newly recogniz...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1989-06-01 00:00:00
abstract::Clinical decision support (CDS) can greatly enhance patient blood management through optimizing ordering and providing patient-specific information. At present, modeling and prediction have small roles in inventory management; they will likely have increasing applications to help guide donor center collections based o...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2019.01.006
更新日期:2019-06-01 00:00:00
abstract::Salmonella, Shigella, and Yersinia cause a well-characterized spectrum of disease in humans, ranging from asymptomatic carriage to hemorrhagic colitis and fatal typhoidal fever. These pathogens are responsible for millions of cases of food-borne illness in the United States each year, with substantial costs measured i...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2015.02.002
更新日期:2015-06-01 00:00:00
abstract::The pharmacologic field that studies antimicrobial pharmacokinetics and pharmacodynamics (PK/PD) has had a major impact on the choice and dosing regimens used for many antibiotics especially those used in the treatment of respiratory tract infections. PK/PD parameters are particularly important in light of increasing ...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2004.03.009
更新日期:2004-06-01 00:00:00
abstract::From the inception of TBS in 1988, it has been well received by the pathology and clinical communities. The need for a unifying system of nomenclature was so great that most of the laboratories in the United States, as well as in numerous countries worldwide, quickly adopted TBS. By 1991, only 2 years after the initia...
journal_title:Clinics in laboratory medicine
pub_type: 共识发展会议,杂志文章,评审
doi:10.1016/s0272-2712(03)00053-2
更新日期:2003-09-01 00:00:00
abstract::Standard business inventory procedures can be cost effective when they are adapted to hospital laboratory inventory management in a 500-bed hospital. The investment in a central laboratory store-room and one additional employee yields financial benefits and indirect service benefits. The system requires consistent use...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1985-12-01 00:00:00
abstract::Yellow fever (YF) is a viral disease, endemic to tropical regions of Africa and the Americas, which principally affects humans and nonhuman primates and is transmitted via the bite of infected mosquitoes. Yellow fever virus (YFV) can cause devastating epidemics of potentially fatal, hemorrhagic disease. Despite mass v...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2010.01.001
更新日期:2010-03-01 00:00:00
abstract::Automation of AST has come quite some way and is here to stay. In particular, fully automated, "hands off" instruments have great appeal to laboratories with a limited number of well-trained and experienced clinical microbiology personnel. None of the evaluated instruments is perfect, but then neither are the standard...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1989-06-01 00:00:00
abstract::A formal therapeutic drug monitoring consultation service (TDMCS) will enhance the clinical benefits of drug level determinations. It can result in decreased length of stay and improved risk management posture. The successful implementation of a TDMCS requires the coordinated efforts of a multidisciplinary team that m...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1987-06-01 00:00:00
abstract::At the start of the twenty-first century, a dramatic change occurred in the clinical laboratory community. Concepts from Metrology, the science of measurement, began to be formally applied to clinical laboratory field methods, resulting in a new appreciation of metrological calibrator traceability. It is a change beca...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2016.09.010
更新日期:2017-03-01 00:00:00
abstract::Diseases due to nontuberculous mycobacteria are increasing in frequency, especially in patients with compromised immunity. A number of "new" mycobacterial species have been described in the last decade, largely as the result of the use of new tools to identify previously unrecognized mycobacteria found in the environm...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2004.05.011
更新日期:2004-09-01 00:00:00