Abstract:
BACKGROUND:Ambulatory blood pressure (ABP) monitoring and carotid-femoral pulse wave velocity (cfPWV) provide important cardiovascular risk information for dialysis patients. This study aims to evaluate the risk factors of cfPWV and the associations between ambulatory blood pressure, especially night-time blood pressure and cfPWV. METHODS:We conducted a cross-sectional study in patients on maintenance hemodialysis. ABP and cfPWV were measured on a midweek interdialytic day. Associations were determined using Pearson's correlation analysis and multiple stepwise regression model. RESULTS:Systolic BPs and pulse pressures, but not diastolic BPs, were significantly and positively associated with cfPWV. In a stepwise regression model, age, diabetes mellitus and all-period systolic BP were independently associated with cfPWV. When day-time and night-time BPs were included in the analysis, respectively, only night-time systolic BP and age remained as independently associated with cfPWV. CONCLUSION:Ambulatory BPs are potent associates of cfPWV and night-time systolic BP, rather than day-time BPs, is an independently predictor of cfPWV. Our results support the view that controlling of nocturnal hypertension provides a unique cardiovascular protection effect.
journal_name
Clin Exp Nephroljournal_title
Clinical and experimental nephrologyauthors
Li X,Jiang Q,Wu W,Xu X,Miao L,Jin L,Xue L,Huang T,Di J,Liu J,He Xdoi
10.1007/s10157-017-1464-zsubject
Has Abstractpub_date
2018-02-01 00:00:00pages
173-178issue
1eissn
1342-1751issn
1437-7799pii
10.1007/s10157-017-1464-zjournal_volume
22pub_type
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