Abstract:
:Oligomerization of thiol-unprotected L-cysteine ethyl ester (Cys-OEt) catalyzed by proteinase K in aqueous solution has been used to synthesize oligo(L-cysteine) (OligoCys) with a well-defined chemical structure and relatively large degree of polymerization (DP) up to 16-17 (average 8.8). By using a high concentration of Cys-OEt, 78.0% free thiol content was achieved. The thermal properties of OligoCys are stable, with no glass transition until 200 °C, and the decomposition temperature could be increased by oxidation. Chemoenzymatically synthesized OligoCys has great potential for use as a thermostable bio-based material with resistance to oxidation.
journal_name
Macromol Bioscijournal_title
Macromolecular bioscienceauthors
Ma Y,Sato R,Li Z,Numata Kdoi
10.1002/mabi.201500255subject
Has Abstractpub_date
2016-01-01 00:00:00pages
151-9issue
1eissn
1616-5187issn
1616-5195journal_volume
16pub_type
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