Scientific validation of cardioprotective attribute by standardized extract of Bombyx mori against doxorubicin-induced cardiotoxicity in murine model.

abstract：:The effect of leaf essential oil of Hoslundia opposita (Vahl) on the haematological parameters of alloxan-induced diabetic rats was investigated. Forty-eight albino rats (Rattus norvegicus), of average weight 132.5 g, were randomly selected into normal and diabetic groups, each with four sub-groups. The rats were trea...

journal_title：EXCLI journal

authors： Muhammad NO,Akolade JO,Usman LA,Oloyede OB

更新日期：2012-09-25 00:00:00

abstract：:Hematopoietic stem cells (HSCs) form a rare population of multipotent stem cells, which give rise to all hematopoietic lineages. HSCs home to bone marrow niches and circulate between blood and bone marrow. Many factors, especially SDF1a, affect the circulation of HSCs, but these have not been fully recognized. SDF1a h...

journal_title：EXCLI journal

authors： Asri A,Sabour J,Atashi A,Soleimani M

更新日期：2016-02-15 00:00:00

abstract：:Phoenix sylvestris (Arecaceae family) known as Indian Date Palm has been identified as a component of traditional medicine against various ailments. The present study was focused on phytochemical screening of crude hexane, dichloromethane and methanol leaf extracts. The crude extracts showed the presence of alkaloids,...

journal_title：EXCLI journal

authors： Sharma DC,Shukla R,Ali J,Sharma S,Bajpai P,Pathak N

更新日期：2016-02-05 00:00:00

abstract：:Spontaneous eye-blinks occur much more often than it would be necessary to maintain the tear film on the eyes. Various factors like cognitive demand, task engagement, or fatigue are influencing spontaneous blink rate. During cognitive information processing there is evidence that blinks occur preferably at moments tha...

journal_title：EXCLI journal

authors： Wascher E,Heppner H,Möckel T,Kobald SO,Getzmann S

更新日期：2015-11-27 00:00:00

abstract：:The essential oil obtained from leaves of Melissa officinalis L. (Family of Lamiaceae) growing in Algeria, was investigated for its chemical composition and in vitro antimicrobial activity. The chemical composition was determined by hydrodistillation and analyzed by GC/MS and GC-FID. Sixty-three compounds were identif...

journal_title：EXCLI journal

authors： Abdellatif F,Boudjella H,Zitouni A,Hassani A

更新日期：2014-07-17 00:00:00

abstract：:Bladder cancer (BC) is the sixth most common malignancy in men and 17th in women. Exosomal long non-coding RNAs (lncRNAs) have been defined as a novel biomarker for BC. The aim of this study is to evaluate the clinical significance of urine exosomal PVT-1, ANRIL and PCAT-1 as a biomarker in BC patients with tumors cla...

journal_title：EXCLI journal

authors： Abbastabar M,Sarfi M,Golestani A,Karimi A,Pourmand G,Khalili E

更新日期：2020-03-04 00:00:00

abstract：:Achillea eriophora (Asteraceae) is a medicinal plant commonly used in Iran. This study was performed to determine the cardiovascular effects of hydroethanolic extract of A. eriophora (HEAE) and the underlying mechanisms in anaesthetized rats. The acute effects of intravenous (i.v.) administration of different doses of...

journal_title：EXCLI journal

authors： Anvari S,Bahaoddini A,Moein M,Khosravi AR

更新日期：2016-12-07 00:00:00

abstract：:We present the case of a 77 year old male patient with metastatic pancreatic neuroendocrine tumor (NET). The patient was initially treated by extensive surgical resection that however, led to severe complications with delayed recovery. During follow-up, a number of new liver metastases were detected, one of which was ...

journal_title：EXCLI journal

authors： Ataeinia B,Loberg C,Kravets H,Beheshti M,von Mallek D,Mottaghy FM,Heinzel A

更新日期：2019-05-21 00:00:00

abstract：:Vitamin D deficiency, common in the population with irritable bowel syndrome (IBS), can induce the main factors that lead to IBS clinical symptoms, such as depression, anxiety, and inflammation. Serotonin (5-HT) plays an important role in the pathophysiology of IBS, and its production and secretion are increased from ...

journal_title：EXCLI journal

authors： Khalighi Sikaroudi M,Mokhtare M,Shidfar F,Janani L,Faghihi Kashani A,Masoodi M,Agah S,Dehnad A,Shidfar S

更新日期：2020-05-19 00:00:00

abstract：:Recently, many articles have reported different levels and distribution of amphetamine hitherto detected in biological fluids now appreciably found in aquatic environment at ng/L levels. Identification and measurement of amphetamine and its metabolites in surface and sewage waters using higher performance liquid chrom...

journal_title：EXCLI journal

authors： Mustapha AO,Ajao UL

更新日期：2011-08-19 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) is a major metabolic regulator that has been shown to be elevated in a number of metabolic disturbances including type 2 diabetes mellitus (T2DM) and the metabolic syndrome, but few studies about the relationship between serum FGF21 and the complications of diabetes have been done. ...

journal_title：EXCLI journal

authors： Mousavi Z,Bonakdaran S,Sahebkar A,Yaghoubi G,Yaghoubi MA,Davoudian N,Mohebbi M

更新日期：2017-11-22 00:00:00

abstract：:Experimentally-induced total sleep deprivation (TSD) and chronic partial sleep restriction (CPSR) leads to the emergence of cognitive impairments. This is hypothesized to result from a consequent neuroinflammation which may also hasten the neurodegenerative processes. Neuroinflammatory markers such as tumor necrosis f...

journal_title：EXCLI journal

authors： Torabi-Nami M,Nasehi M,Zarrindast MR

更新日期：2013-04-14 00:00:00

abstract：:Recently, bioinformatics has advanced to the level that it allows almost accurate prediction of molecular interactions that hold together a protein and a ligand in the bound state. For instance, the program AutoDock has been developed to provide a procedure for predicting the interaction of small molecules with macrom...

journal_title：EXCLI journal

authors： Rizvi SM,Shakil S,Haneef M

更新日期：2013-09-23 00:00:00

abstract：:The present study deals with the isolation and partial purification of bioactive compounds from the crude methanol extracts of the leaves of Ageratum houstonianum (Asteraceae). The quantification and the identification of compounds in the crude extract and active bands isolated by preparative TLC were accomplished usi...

journal_title：EXCLI journal

authors： Zeeshan M,Rizvi SM,Khan MS,Kumar A

更新日期：2012-02-28 00:00:00

abstract：:The present study is conducted to determine the potential mechanisms of Boron compounds, boric acid (BA) and borax (BX), on genotoxicity of zebrafish Danio rerio for 24, 48, 72 and 96-hours acute exposure (level:1, 4, 16, 64 mg/l BA and BX) in semi-static bioassay experiment. For that purpose, peripheral erythrocytes ...

journal_title：EXCLI journal

authors： Gülsoy N,Yavas C,Mutlu Ö

更新日期：2015-07-30 00:00:00

abstract：:Endometriosis is defined by presence of endometrial-like-tissue outside the uterus. Recently, ectopic endometriotic lesions have been suggested to originate by abnormal differentiation of endometrial mesenchymal stem cells (eMSCs). MicroRNAs (miRNAs) play an important role in the pathophysiology of endometriosis. Thro...

journal_title：EXCLI journal

authors： Abdel-Rasheed M,Nour Eldeen G,Mahmoud M,ElHefnawi M,Abu-Shahba N,Reda M,Elsetohy K,Nabil M,Elnoury A,Taha T,Azmy O

更新日期：2017-06-14 00:00:00

abstract：:Considering the therapeutic values of bioflavonoids in colon cancer treatment, six 2'-hydroxy chalcones (C1-C6) were synthesized, characterized and screened for in vitro cytotoxicity on human colon carcinoma (HCT116) and African green monkey kidney epithelial cells (Vero). Only C5 showed selective cytotoxicity against...

journal_title：EXCLI journal

authors： Pande AN,Biswas S,Reddy ND,Jayashree BS,Kumar N,Rao CM

更新日期：2017-04-03 00:00:00

abstract：:Dibutyltin dichloride (DBTC) is an organotin compound used as model for acute and chronic pancreatitis. Oxidative stress is one of the mechanisms of propagation of acinar cell injury in acute pancreatitis. Selenium is an essential cofactor in the antioxidant glutathione peroxidase pathway. Selenium levels are describe...

journal_title：EXCLI journal

authors： Merkord J,Görl N,Lemke M,Berg A,Weber H,Ramer R,Hennighausen G

更新日期：2017-02-16 00:00:00

abstract：:Serum concentration of lipids and lipoproteins changes during the course of acute coronary syndrome as a consequence of the inflammatory response. The objective of this study was to evaluate the effect of acute myocardial infarction (AMI) on the levels of lipid profile and inflammatory markers. We investigated 400 pat...

journal_title：EXCLI journal

authors： Shrivastava AK,Singh HV,Raizada A,Singh SK

更新日期：2015-04-10 00:00:00

abstract：:Healthcare professionals, especially nurses and pre-hospital emergency (PHE) staff, are influenced by many stressors due to their responsibility to provide comfort as well as care and treatment of patients. The aim of the present study was to identify and rank the occupational stressors in nurses and PHE staff using F...

journal_title：EXCLI journal

authors： Rajabi F,Jahangiri M,Molaeifar H,Honarbakhsh M,Farhadi P

更新日期：2018-08-20 00:00:00

abstract：:Patients with diabetes tend to have an increased risk of osteoporosis that may be related to hyperglycemia. In vitro evidence has shown that high glucose can affect the proliferation and osteogenic differentiation of mesenchymal stem cells (MSCs). Tissue regeneration depends mainly on MSCs. However, the exact mechanis...

journal_title：EXCLI journal

authors： Wang J,Wang B,Li Y,Wang D,Lingling E,Bai Y,Liu H

更新日期：2013-06-27 00:00:00

abstract：:To date, a number of significant herbal drug interactions have their origins in the alteration of cytochrome P450 (CYP) activity by various phytochemicals. Among the most noteworthy are those involving St. John's wort and drugs metabolized by human CYP3A4 enzyme. This review article is the continued work from our prev...

journal_title：EXCLI journal

authors： Wanwimolruk S,Phopin K,Prachayasittikul V

更新日期：2014-08-20 00:00:00

abstract：:Unlike conventional materials that covalent bonds connecting atoms as the major force to hold the materials together, supramolecular biomaterials rely on noncovalent intermolecular interactions to assemble. The reversibility and biocompatibility of supramolecular biomaterials render them with diverse range of function...

journal_title：EXCLI journal

authors： Guo J,Tian C,Xu B

更新日期：2020-08-05 00:00:00

abstract：:A series of phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides (TTa-TTg) were synthesized by the ring closure reaction of phenyl-1-(thiophen-2-yl) prop-2-en-1-ones with thiosemicarbazide in alcoholic basic medium. All the final derivatives were evaluated for their antidepressant and neurotoxicity scre...

journal_title：EXCLI journal

authors： Mathew B,Suresh J,Anbazhagan S

更新日期：2014-04-29 00:00:00

abstract：:Renin Angiotensin Aldosterone System (RAAS) plays an important role in the development of hypertension. On the other hand, hypertension is a well-known and independent risk factor for cognitive impairment. The aim of the present study was to evaluate the relationship of blood pressure control, plasma angiotensin pepti...

journal_title：EXCLI journal

authors： Sen S,Gürel N,Ufuktepe B,Özünal ZG,Büyüklü Ç,Üresin Y

更新日期：2017-03-10 00:00:00

abstract：:To investigate whether offspring sex ratio at birth (SRB) was associated with maternal breast cancer risk, the present case-control study and a meta-analysis of literature were done. A total of 389 female breast cancer patients who had at least one offspring participated in the study. From general population 356 healt...

journal_title：EXCLI journal

authors： Saadat M

更新日期：2010-07-26 00:00:00

abstract：:Sleep deprivation affects all aspects of health. Adverse health effects by sleep deviation are still underestimated and undervalued in clinical practice and, to a much greater extent in monitoring human health. We hypothesized that sleep deprivation-induced mild organ injuries; oxidative stress and inflammation might ...

journal_title：EXCLI journal

authors： Periasamy S,Hsu DZ,Fu YH,Liu MY

更新日期：2015-05-18 00:00:00

abstract：:[This retracts the article DOI: 10.17179/excli2015-642.]. ...

journal_title：EXCLI journal

authors： Finelli C,Crispino P,Gioia S,La Sala N,D'amico L,La Grotta M,Miro O,Colarusso D

更新日期：2016-09-19 00:00:00

abstract：:Oxidative stress is the common underlying mechanism of damage in ischemic stroke. Therefore, we aimed to evaluate the possible protective effects of polyhydroxylated fullerene derivatives on brain infarction and oxidative/nitrosative stress in a rat model of ischemic stroke. The experiment was performed by four groups...

journal_title：EXCLI journal

authors： Vani JR,Mohammadi MT,Foroshani MS,Jafari M

更新日期：2016-06-20 00:00:00

abstract：:R273H mutant p53 is a DNA-contact mutant that renders p53 dysfunctional due to a single substitution of Arg273 for His273. Rescuing R273 mutant p53 implies that a competent molecule would have to bind to the site of DNA-contact hot spots to complement the loss of contact with the DNA-binding domain. Here, curcumin, fl...

journal_title：EXCLI journal

authors： Malami I,Muhammad A,Etti IC,Waziri PM,Alhassan AM

更新日期：2017-12-08 00:00:00