The rabbit immune system: cells regulating the proliferative response of purified T cells to concanavalin A and phytohaemagglutinin.

Abstract:

:T cell specific, B cell specific and Ia specific polyclonal antisera, as well as monoclonal antibodies, were employed to characterize cells involved in regulation of T cells, proliferating upon stimulation with concanavalin A or phytohaemagglutinin. Evidence for Ia+ accessory cells was obtained and the constellation of membrane antigens was determined by cytotoxic cell kill with the above mentioned antibodies. Help given by Ia+ cells was not blocked by polyclonal antibody against Ia, in the absence of complement. There was indirect evidence that a fraction of helper/accessory cells were Ia-.

journal_name

Immunol Lett

journal_title

Immunology letters

authors

Ponsard DC,Chou CT,Cinader B,Dubiski S

doi

10.1016/0165-2478(86)90127-6

subject

Has Abstract

pub_date

1986-08-01 00:00:00

pages

63-9

issue

1-2

eissn

0165-2478

issn

1879-0542

pii

0165-2478(86)90127-6

journal_volume

13

pub_type

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