Exposure to Parental Smoking in Childhood is Associated with High C-Reactive Protein in Adulthood: The Cardiovascular Risk in Young Finns Study.

abstract：AIM:To evaluate the effect of statin therapy on the decrease of common carotid artery intima-media thickness (CCA-IMT) compared to placebo or usual care. METHODS:A systematic search of electronic databases (MEDLINE, EMBASE, and Cochrane Center Register) up to December 2011 was performed. Two reviewers independently de...

journal_title：Journal of atherosclerosis and thrombosis

authors： Huang Y,Li W,Dong L,Li R,Wu Y

更新日期：2013-01-01 00:00:00

abstract：:The agarose gel electrophoresis and differential staining system is an easy and quick method for analyzing the serum lipid composition of each lipoprotein fraction. It has been reported in adults that measured values obtained by this method strongly correlated with those obtained by ultracentrifugation. The aim of thi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kuromori Y,Okada T,Miyashita M,Harada K

更新日期：2006-10-01 00:00:00

abstract：AIM:Myriad biological effects of leptin may lead to broad therapeutic applications for various metabolic diseases, including diabetes and its complications; however, in contrast to its anorexic effect, the molecular mechanisms underlying adipopenic and glucose-lowering effects of leptin have not been fully understood. ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Takanashi M,Taira Y,Okazaki S,Takase S,Kimura T,Li CC,Xu PF,Noda A,Sakata I,Kumagai H,Ikeda Y,Iizuka Y,Yahagi N,Shimano H,Osuga JI,Ishibashi S,Kadowaki T,Okazaki H

更新日期：2017-11-01 00:00:00

abstract：AIM:In Japan, heart disease and cerebral ischemic disease are major causes of death. A decrease in the level of low-density lipoprotein cholesterol (LDL-C) through intensive treatment with statins positively correlates with a reduction in the volume of plaques in patients with cardiovascular disease. The METEOR trial, ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kurabayashi M,Sakuma I,Kawamori R,Daida H,Yamazaki T,Yoshida M,Hata M,Masuda I,Kaku K,Yokoi H,Kishimoto J,Nohara R

更新日期：2010-04-30 00:00:00

abstract：AIM:Sarcopenic obesity (SO) is closely associated with cardiovascular disease (CVD) in elderly women. Increases in body fat and decreases in muscle mass are closely associated with increased carotid intima-media thickness (CIMT). The aim of this study was to examine the influence of a 24-week aerobic and resistance tra...

journal_title：Journal of atherosclerosis and thrombosis

authors： Park J,Kwon Y,Park H

更新日期：2017-11-01 00:00:00

abstract：AIM:Angiotensin-converting enzyme inhibitors (ACEIs) have been shown to block matrix metalloproteinase (MMP)-9 activity, which plays a role in atherogenesis. MMP-9 activity of macrophages is increased during foam cell formation. To investigate the contribution of ACEIs to foam cell formation, we studied the effects of ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kojima C,Ino J,Ishii H,Nitta K,Yoshida M

更新日期：2010-02-01 00:00:00

abstract：AIM:To examine the association between renal vasculature changes and generalized atherosclerosis using autopsy cases. METHODS:We histologically examined 107 autopsy patients(mean age, 68.4 years; 64% men; 81% non-CVD) to investigate the association between renal vasculature changes and generalized atherosclerosis. We ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Iwakiri T,Sato Y,Matsuura Y,Hatakeyama K,Marutsuka K,Yamashita A,Fujimoto S,Kitamura K,Asada Y

更新日期：2014-01-01 00:00:00

abstract：AIM:Obesity and metabolic syndrome (MetS) frequently coexist and are both important risk factors for cardiovascular disease. However, the pathophysiological role of obesity without MetS, also referred to as metabolically healthy obesity (MHO), remains unclear. In this study, we aim to clarify the effect of MHO on the d...

journal_title：Journal of atherosclerosis and thrombosis

authors： Itoh H,Kaneko H,Kiriyama H,Yoshida Y,Nakanishi K,Mizuno Y,Daimon M,Morita H,Yatomi Y,Yamamichi N,Komuro I

更新日期：2020-02-01 00:00:00

abstract：AIM:The INK4b-ARF-INK4a locus in the chromosome 9p21 region is known to play an important role in the development of atherosclerosis. The INK4/ARF transcript p16(INK4a) inhibits the activity of the cyclin-dependent kinases CDK4/CDK6 and arrests cell-cycle progression. CDK inhibitors also regulate G1/S phase progression...

journal_title：Journal of atherosclerosis and thrombosis

authors： Bayoglu B,Arslan C,Gode S,Kaya Dagistanli F,Arapi B,Burc Deser S,Dirican A,Cengiz M

更新日期：2014-01-01 00:00:00

abstract：AIM:To compare the responsiveness to clopidogrel in patients who were prescribed two different types of statins, atorvastatin vs. rosuvastatin, following percutaneous coronary intervention. METHODS:A total of 915 patients were randomized according to the antiplatelet therapy strategy in the CILON-T trial. In this subg...

journal_title：Journal of atherosclerosis and thrombosis

authors： Suh JW,Cha MJ,Lee SP,Chae IH,Bae JH,Kwon TG,Bae JW,Cho MC,Rha SW,Kim HS

更新日期：2014-01-01 00:00:00

abstract：AIM:Hypercholesterolemic patients with inflammation are at high risk for cardiovascular events. Statins exert anti-inflammatory action independent of their cholesterol-lowering action. This study sought to clarify whether statin therapy reduces inflammatory markers in hypercholesterolemic patients and to determine fact...

journal_title：Journal of atherosclerosis and thrombosis

authors： Horiuchi Y,Hirayama S,Soda S,Seino U,Kon M,Ueno T,Idei M,Hanyu O,Tsuda T,Ohmura H,Miida T

更新日期：2010-07-30 00:00:00

abstract：AIM:Since we previously reported that lower levels of HDL-C may be most useful for predicting coronary artery disease (CAD) as assessed by multi-detector row computed tomography (MDCT), we sought to confirm, among the levels of LDL-C, HDL-C, non-HDL-C (total cholesterol minus HDL-C) and the ratio of LDL-C to HDL-C (LDL...

journal_title：Journal of atherosclerosis and thrombosis

authors： Shiga Y,Miura S,Mitsutake R,Kawamura A,Uehara Y,Saku K

更新日期：2010-08-31 00:00:00

abstract：BACKGROUND:Although insulin resistance (IR) is present in non-diabetic subjects, it is unknown whether IR affects statin treatment. We assessed the relationship between IR and the changes of lipid profile in patients with hyperlipidemia treated by atorvastatin. METHODS:Forty-four non-diabetic patients were included. H...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yoshitomi Y,Ishii T,Kaneki M,Tsujibayashi T,Sakurai S,Nagakura C,Miyauchi A

更新日期：2005-01-01 00:00:00

abstract：:Both hyperthyroidism and hypothyroidism affect the cardiovascular system. Hypothyroidism is known to be associated with enhanced atherosclerosis and ischemic heart diseases. The accelerated atherosclerosis in the hypothyroid state has been traditionally ascribed to atherogenic lipid profile, diastolic hypertension, an...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ichiki T

更新日期：2016-01-01 00:00:00

abstract：AIM:Coronary artery stenosis (CAS) ≥ 50% frequently coexists in patients with acute ischemic cerebrovascular disease (AICVD), which portends unfavorable outcomes. We sought to examine whether patients with AICVD with CAS had more severe and more diffused cervicocephalic atherosclerosis (CA). METHODS:Patients with AICV...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kong Q,Ma X,Wang C,Feng W,Ovbiagele B,Zhang Y,Du X

更新日期：2019-09-01 00:00:00

abstract：AIM:Moderate alcohol consumption appears to confer some protection against coronary heart disease, which is related to an increase in high-density lipoprotein cholesterol (HDL-C). The genotype of aldehyde dehydrogenase 2 (ALDH2) is closely related to alcohol metabolism but a relationship between ALDH2 genotypes and HDL...

journal_title：Journal of atherosclerosis and thrombosis

authors： Wada M,Daimon M,Emi M,Iijima H,Sato H,Koyano S,Tajima K,Kawanami T,Kurita K,Hunt SC,Hopkins PN,Kubota I,Kawata S,Kato T

更新日期：2008-08-01 00:00:00

abstract：AIM:Epicardial adipose tissue (EAT) is implicated in the development of coronary atherosclerosis.We sought to investigate the association between the EAT thickness and presence of multivessel disease (MV) in patients with acute myocardial infarction (AMI). METHODS:We enrolled 45 consecutive patients with AMI who under...

journal_title：Journal of atherosclerosis and thrombosis

authors： Fukamachi D,Higuchi Y,Hiro T,Takayama T,Kanai T,Sudo M,Nishida T,Iida K,Saito S,Hirayama A

更新日期：2015-01-01 00:00:00

abstract：:Statins are the main treatment for hypercholesterolemia and the cornerstone of atherosclerotic cardiovascular disease prevention. Many patients taking statins report muscle-related symptoms, one of the most important causes of statin treatment discontinuation, which is associated with an increased risk of cardiovascul...

journal_title：Journal of atherosclerosis and thrombosis

authors： Alonso R,Cuevas A,Cafferata A

更新日期：2019-03-01 00:00:00

abstract：AIM:To study atherosclerosis risk in diabetes, we investigated ATP-binding cassette transporter A1 (ABCA1) expression and high-density lipoprotein (HDL) biogenesis in the liver and hepatocytes under hyperglycemic conditions. METHODS AND RESULTS:In streptozotocin-induced diabetic mice, plasma HDL decreased while ABCA1 ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tsujita M,Hossain MA,Lu R,Tsuboi T,Okumura-Noji K,Yokoyama S

更新日期：2017-11-01 00:00:00

abstract：:Coronary artery calcification (CAC) is a well-established surrogate marker of the total burden of coronary atherosclerosis. The CAC score, as measured on coronary computed tomography (CT), is associated with the prevalence of coronary artery disease (CAD) as well as cardiovascular morbidity and mortality. The CAC scor...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yamamoto H,Kitagawa T,Kihara Y

更新日期：2014-01-01 00:00:00

abstract：AIM:This study aimed to examine whether cardiorespiratory fitness (CRF) is associated with arterial stiffening, evaluated using the cardio-ankle vascular index (CAVI), independent of visceral fat (VF) in middle-aged and elderly Japanese men. We also examined whether the relationship between CRF and the CAVI is modified...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tanisawa K,Ito T,Sun X,Kawakami R,Oshima S,Gando Y,Cao ZB,Sakamoto S,Higuchi M

更新日期：2015-01-01 00:00:00

abstract：:A number of effective drugs have been developed through animal experiments, contributing to the health of many patients. In particular, the WHHL rabbit family (WHHL rabbits and its advanced strains (coronary atherosclerosis-prone WHHL-CA rabbits and myocardial infarction-prone WHHLMI rabbits) developed at Kobe Univers...

journal_title：Journal of atherosclerosis and thrombosis

authors： Shiomi M

更新日期：2020-02-01 00:00:00

abstract：:Patients with chronic kidney disease (CKD) are at an increased risk not only for end-stage kidney disease (ESKD) but also for cardiovascular disease (CVD). In this review article, we summarize the current evidence of CKD as a high-risk condition for CVD based on reports from Japan and other countries to draw attention...

journal_title：Journal of atherosclerosis and thrombosis

authors： Shoji T,Abe T,Matsuo H,Egusa G,Yamasaki Y,Kashihara N,Shirai K,Kashiwagi A,Committee of Renal and Peripheral Arteries, Japan Atherosclerosis Society.

更新日期：2012-01-01 00:00:00

abstract：AIM:The Framingham risk score (FRS) is one of the standard tools used to predict the incidence of coronary heart disease (CHD). No previous study has investigated its efficacy for a Japanese population cohort. The purpose of this study was to develop new coronary prediction algorithms for the Japanese population in the...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nishimura K,Okamura T,Watanabe M,Nakai M,Takegami M,Higashiyama A,Kokubo Y,Okayama A,Miyamoto Y

更新日期：2014-01-01 00:00:00

abstract：AIM:Inflammation plays a critical role in the development of atherosclerotic plaque, and lipopolysaccharide (LPS) is a potentially important source of inflammation. The aim of this study was to develop a rabbit model of spontaneous thrombosis mimicking the pathophysiological and morphological characteristics of atheros...

journal_title：Journal of atherosclerosis and thrombosis

authors： Liu H,Hou J,Hu S,Du X,Fang Y,Jia H,Feng L,Zhang L,Du J,Zhao Q,Xie Z,Yu B

更新日期：2014-01-01 00:00:00

abstract：AIMS:Small arteries can be visualized in the ocular fundus, and findings of retinopathy based on Scheie classification are often applied to evaluate the impact of hypertension and atherosclerosis. However, the relationship between damage in the large and small arteries has not been investigated sufficiently, especially...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sugiura T,Dohi Y,Takagi Y,Yokochi T,Yoshikane N,Suzuki K,Tomiishi T,Nagami T,Iwase M,Takase H,Seo Y,Ohte N

更新日期：2020-11-25 00:00:00

abstract：AIM:A positive association between metabolic syndrome (MetS) and periodontal status has recently been noted. However, no study has evaluated the relationship by sex and in a general urban population using the uniform definition proposed in the 2009 Joint Interim Statement. The aim of this study was to clarify the relat...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kikui M,Kokubo Y,Ono T,Kida M,Kosaka T,Yamamoto M,Watanabe M,Maeda Y,Miyamoto Y

更新日期：2017-05-01 00:00:00

abstract：AIM:Angiotensin (Ang) II-induced abdominal aortic aneurysm (AAA) in apoE-deficient mice has been used as a model of human AAA, but it has been unclear why the progression of AAA continues after stopping the Ang II infusion. The involvement of vascular Ang II-forming enzymes in the progression of AAA was studied. METHO...

journal_title：Journal of atherosclerosis and thrombosis

authors： Inoue N,Muramatsu M,Jin D,Takai S,Hayashi T,Katayama H,Kitaura Y,Tamai H,Miyazaki M

更新日期：2009-06-01 00:00:00

abstract：AIM:Nephrotic syndrome (NS) is associated with an increased rate of cardiovascular events. The YKL-40 level is associated with atherosclerosis, endothelial dysfunction and proteinuria in renal and non-renal populations. The aim of this study was to investigate the relationships between the YKL-40 level and both vascula...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kocyigit I,Gungor O,Dogan E,Karadavut S,Karakukcu C,Eroglu E,Orscelik O,Unal A,Dogan A,Sipahioglu MH,Tokgoz B,Oymak O

更新日期：2015-01-01 00:00:00

abstract：AIM:The importance of sarcopenia in cardiovascular diseases has been recently demonstrated. This study aims to examine whether skeletal muscle mass (SMM), an important component of sarcopenia, is associated with an increased risk of poor outcome in patients after ST-segment elevation myocardial infarction (STEMI). MET...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sato R,Akiyama E,Konishi M,Matsuzawa Y,Suzuki H,Kawashima C,Kimura Y,Okada K,Maejima N,Iwahashi N,Hibi K,Kosuge M,Ebina T,von Haehling S,Anker SD,Tamura K,Kimura K

更新日期：2020-12-01 00:00:00