Abstract：
:Objective Hypertrophic cardiomyopathy (HCM) is associated with a risk of sudden cardiac death (SCD). Several models have been developed to estimate SCD risk and guide preventive therapy. The comparison of the previous 2003 with novel 2014 SCD risk models have never been studied. Methods Over a year we included 103 consecutive HCM patients without previous cardiac arrest and/or ICD implanted (65% males; aged 53.3 ± 13.9 years; mean EF 62.3 ± 18%). The SCD risk was calculated for each patient. Results Based on the 2003 model, patients had following scores: 0 points -15 (15%) patients, 1-28 (27%), 2-34 (33%), 3-18 (17%), ≥ 4-8 (8%). According to the 2014 model 83 (80%) had low risk, 12 (12%) intermediate risk, and only 8 (8%) high risk. Patients who had an intermediate or high risk in the 2003 model but a low risk in 2014 model were the oldest, experienced less frequently syncope and nsVT, but had more often abnormal blood pressure response to exercise and an intermediate LVOT gradient in comparison to the patients who had consistently low or high risk in both models. Conclusions Calculation of SCD risk using two models provides completely different risk estimates and consequently different guidance on SCD primary prevention. According to the 2003 model up to 85% of patients have indications for ICD, whereas based on the 2014 risk model only 20% of the patients had non-negligible SCD risk and are candidates for ICD therapy. SCD risk markers, used in the 2003 and 2014 models, have various discriminating power.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Rubis P,Biernacka-Fijalkowska B,Khachatryan L,Karabinowska A,Faltyn P,Dzwiecka E,Wisniowska-Smialek S,Tomkiewcz-Pająk L,Podolec Pdoi
10.1080/00015385.2017.1310843subject
Has Abstractpub_date
2017-08-01 00:00:00pages
446-452issue
4eissn
0001-5385issn
1784-973Xjournal_volume
72pub_type
杂志文章abstract：:Hereditary diseases under the age of 35 are the most common underlying heart disease, leading to sudden cardiac death (SCD) in competitive sports, while in older people, atherosclerotic coronary artery disease (CAD) is the main cause. The following preventive measures are recommended: (a) The pre-participation cardiov...
journal_title：Acta cardiologica
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更新日期：2021-01-08 00:00:00
abstract：:The authors present a case of permanent atrial standstill with syncopal attacks, in a patient with chronic Chagas' Heart Disease. The recognition of this dysrhythmia was based upon the conventional and intracavity electrocardiographic tracings in addition to phonomecanographic and hemodynamic data. The recording of th...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：:We report the case of a 73-year-old man admitted to our hospital for acute hepatic failure. Antemortem diagnosis of systemic AA amyloidosis was made because of typical electrocardiographic and echocardiographic findings, in the absence of the classic clinical picture of kidney involvement. ...
journal_title：Acta cardiologica
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更新日期：2010-08-01 00:00:00
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journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
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journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.62.5.2023412
更新日期：2007-10-01 00:00:00
abstract：:An 18-year-old male patient, known with familial hypertrophic obstructive cardiomyopathy underwent a septal myectomy 10 years ago for significant left ventricular outflow tract (LVOT) obstruction. During follow-up a progressive increase in LVOT gradient was noted in association with severe mitral valve regurgitation. ...
journal_title：Acta cardiologica
pub_type： 杂志文章
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更新日期：2008-04-01 00:00:00
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journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.59.5.2005229
更新日期：2004-10-01 00:00:00
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journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.1080/ac.69.2.3017300
更新日期：2014-04-01 00:00:00
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pub_type： 杂志文章
doi：10.1080/ac.67.5.2174134
更新日期：2012-10-01 00:00:00
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journal_title：Acta cardiologica
pub_type： 临床试验,杂志文章
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更新日期：2011-10-01 00:00:00
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journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
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doi：10.2143/AC.58.5.2005309
更新日期：2003-10-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2006-04-01 00:00:00
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pub_type： 杂志文章
doi：10.2143/AC.63.3.1020306
更新日期：2008-06-01 00:00:00
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pub_type： 杂志文章
doi：10.2143/AC.57.3.2005392
更新日期：2002-06-01 00:00:00
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更新日期：2010-12-01 00:00:00
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更新日期：2015-12-01 00:00:00
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pub_type： 杂志文章
doi：10.2143/AC.55.5.2005757
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pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
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journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
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更新日期：2019-12-01 00:00:00
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更新日期：2013-04-01 00:00:00
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journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:The clinical, hemodynamic findings and surgical results of forty patients with rheumatic tricuspid stenosis are presented. It is concluded that tricuspid stenosis is a frequent lesion. Its signs should be sought carefully and documented by simultaneous measurements of the right ventricular diastolic and right atrial p...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
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journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.63.2.2029528
更新日期：2008-04-01 00:00:00
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doi：
更新日期：1984-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1080/ac.67.3.2160721
更新日期：2012-06-01 00:00:00
