Relationships between transporter expression and the status of BRAF V600E mutation and F-18 FDG uptake in papillary thyroid carcinomas.

abstract：:Atrial natriuretic peptide (ANP) is released from the atria and acts to regulate blood volume and pressure. The release of ANP appears to be stimulated by atrial distension, initiated by stretch on the cardiocytes. The purpose of the present study was to develop an assay that would allow for the detection of ANP relea...

journal_title：Endocrine research

authors： Miller HA 3rd,Southerland CM

更新日期：1990-01-01 00:00:00

abstract：:The presence of vasoactive intestinal peptide and neuropeptide Y in thyroid nerves and their effects on thyroid blood flow are well known. However, the effects of these two neuropeptides on the various processes involved in thyroid hormone biosynthesis and release have not been fully explored. We have now tested these...

journal_title：Endocrine research

authors： Pietrzyk Z,Michalkiewicz M,Huffman LJ,Hedge GA

更新日期：1992-01-01 00:00:00

abstract：:Purpose: Transthyretin (TTR) is a protein with a growing number of biological functions in addition to its well-established binding and circulatory transport of thyroxine, and indirect retinoid transport through interaction with retinol-binding protein. Misfolded and aggregated wild-type and mutant TTRs are involved i...

journal_title：Endocrine research

authors： Fong VH,Wong S,Jintaridhi P,Vieira A

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:Thyroglobulin (Tg) assessment in the needle washout after fine-needle aspiration biopsy (FNAB) of a suspicious neck lymph node (LN) is known to improve the diagnostic accuracy in patients with papillary thyroid cancer (PTC). However, there is still controversy on the best diagnostic cut-off levels for FNAB-Tg a...

journal_title：Endocrine research

authors： Konca Degertekin C,Yalcin MM,Cerit T,Ozkan C,Kalan I,Iyidir OT,Altinova AE,Akturk M,Toruner F,Akin M,Cakir N

更新日期：2016-11-01 00:00:00

abstract：:Mouse Y1 adrenocortical tumor cells harbor amplified and overexpressed c-Ki-ras gene, displaying relatively high constitutive levels of Ras x GTP. Here we report that Y1 cells also constitutively display high levels of phosphorylated AKT/PKB, that are dependent on Ras x GTP and PI3K. ACTH rapidly causes dephosphorylat...

journal_title：Endocrine research

authors： Forti FL,Armelin HA

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:Monthly regimen of minodronate for osteoporosis more than two years has not been reported yet. The aim of this study is to elucidate the effect of monthly minodronate (M-MIN) on bone mineral density (BMD) and serum pentosidine (Pen) during 27 months. MATERIALS AND METHODS:The study consisted of 52 newly treate...

journal_title：Endocrine research

authors： Ohishi T,Fujita T,Suzuki D,Nishida T,Yamamoto K,Okabayashi R,Ushirozako H,Banno T,Matsuyama Y

更新日期：2017-08-01 00:00:00

abstract：:Type 1 angiotensin II (AII) receptors (AT1 receptors), besides stimulation of aldosterone secretion, seem to transduce the growth factor-like activity of AII on glomerulosa cells. Although a local renin-angiotensin system and AII synthesis have been found in human adrenals and aldosteronomas, it is unclear whether ald...

journal_title：Endocrine research

authors： Sarzani R,Opocher G,Dessì-Fulgheri P,Paci V,Cola G,Rocco S,Vianello B,Mantero F,Rappelli A

更新日期：1995-02-01 00:00:00

abstract：:The prostate gland of humans and other animals has the unique function of accumulating and secreting extraordinarily high levels of citrate. The prostate secretory epithelial cells synthesize citrate which, due to a limiting mitochondrial (m-) aconitase, accumulates rather than being oxidized. Thus citrate is essentia...

journal_title：Endocrine research

authors： Costello LC,Liu Y,Zou J,Franklin RB

更新日期：2000-02-01 00:00:00

abstract：:The sexual dimorphism of life span and caloric restriction effects in numerous species suggest that estradiol (E2) is protective against oxidative damage. The only direct test of E2's protective effect in mice against in vivo oxidative stress to date may have been confounded by E2's direct chemical action as an antiox...

journal_title：Endocrine research

authors： Bokov AF,Ko D,Richardson A

更新日期：2009-01-01 00:00:00

abstract：:T3 receptors are ligand-dependent transcriptional activators that can stimulate gene expression resulting in growth and development. In this study T3 binding sites on isolated liver nuclei are demonstrated in the teleost Anabas testudineus. The effect of hypothyroidism and feeding of polyunsaturated fatty acids (PUFA)...

journal_title：Endocrine research

authors： Shameena B,Renuka TR,Varghese S,Paulose CS,Oommen OV

更新日期：2001-08-01 00:00:00

abstract：:There are several published reports on the prevalence of low vitamin D levels in otherwise healthy Indian population. Vitamin D deficiency has shown variable effect on muscle performance and strength but there is paucity of data on the effect of vitamin D deficiency on muscle energy metabolism. The present study was p...

journal_title：Endocrine research

authors： Rana P,Marwaha RK,Kumar P,Narang A,Devi MM,Tripathi RP,Khushu S

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:The scavenger receptor class B type I (SR-BI) is a key component in the reverse cholesterol transportation. The aim of this study was to assess the association between exon1 (G → A) polymorphism of SR-BI gene and lipid profiles among the Tehran Lipid and Glucose Study (TLGS) population. MATERIALS AND METH...

journal_title：Endocrine research

authors： Faam B,Daneshpour MS,Hedayati M,Halalkhor S,Mansournia MA,Zarkesh M,Azizi F

更新日期：2014-01-01 00:00:00

abstract：:The steady state level of most cellular phosphoproteins is dependent on the relative catalytic activities of intracellular protein kinases and phosphatases. In adrenal cortex, ACTH acts through PKA activation and Ser/Tre phosphorylation. Phosphatases involved in this pathway are not completely described, particularly ...

journal_title：Endocrine research

authors： Cornejo Maciel F,Paz C,Neuman MI,Podestá EJ

更新日期：1998-08-01 00:00:00

abstract：:Activation of calcium-activated, phospholipid-dependent protein kinase C by phorbol esters such as 12-O-tetradecanoyl-phorbol-13-acetate (TPA) has been shown to mediate release of hormones in many systems. To investigate the role of protein kinase C in the mechanism of pituitary ACTH release, we studied the effect of ...

journal_title：Endocrine research

authors： Sobel DO

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the effect of pioglitazone on serum uric acid (UA) levels and several diabetic parameters in drug-naïve subjects with type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS:The patients (n = 68) received 7.5-30 mg/day pioglitazone monotherapy. They were divided into t...

journal_title：Endocrine research

authors： Kutoh E,Hori T

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Tetraiodothyroacetic acid (tetrac) and its nanoparticulate formulation (Nanotetrac) act at a cell surface receptor to block angiogenesis and tumor cell proliferation. OBJECTIVE:The complex anti-angiogenic properties of tetrac and Nanotetrac caused us to search in the literature and in certain of our unpubli...

journal_title：Endocrine research

authors： Davis PJ,Glinsky GV,Lin HY,Incerpi S,Davis FB,Mousa SA,Tang HY,Hercbergs A,Luidens MK

更新日期：2013-01-01 00:00:00

abstract：:Tumor-promoting phorbol esters are believed to affect cell functions by activating a Ca+2-and lipid-dependent protein kinase (protein kinase C). 12-0-Tetradecanoyl phorbol-13-acetate (TPA) inhibits LH stimulation of progesterone (P) accumulation in rat granulosa cells. To determine the mechanisms by which TPA inhibits...

journal_title：Endocrine research

authors： Kawai Y,Clark MR

更新日期：1986-01-01 00:00:00

abstract：:The question of whether ethanol's (ETOH's) known suppressive effect on serum luteinizing hormone (LH) could be mediated directly at the anterior pituitary level was addressed by examining the effects of ETOH in vitro on release of LH from cultured male rat pituitary cells. The impact of added ethanol concentrations ra...

journal_title：Endocrine research

authors： Emanuele MA,Tentler J,Emanuele NV,Reda D,Kirsteins L,Lawrence AM

更新日期：1989-01-01 00:00:00

abstract：:Congenital adrenal hyperplasia due to 21-hydroxylase (21-OH) deficiency is HLA-linked. The haplotype HLA-(A3);Bw47;DR7 is strongly associated with 21-OH deficiency and always carries a null allele at the complement C4A (Rodgers) locus. It seemed likely that this haplotype carries a deletion encompassing both the C4A a...

journal_title：Endocrine research

authors： White PC,Dupont B,New MI

更新日期：1984-01-01 00:00:00

abstract：AIMS/HYPOTHESIS:Glucose tolerance progressively declines with age, and there is a high prevalence of type 2 diabetes in the elderly people. Previous studies have reported the sex differences in risk for type 2 diabetes, especially in the elderly people, whereas reasons for these sex differences remain poorly understood...

journal_title：Endocrine research

authors： Li T,Jiao W,Li W,Li H

更新日期：2016-08-01 00:00:00

abstract：:Plasminogen activator inhibitor-1 (PAI-1) levels were found to be associated with obesity, indicating that adipocytes might influence PAI-1 plasma levels. In addition, the 4G/5G promoter polymorphism of the PAI-1 gene possibly modulates PAI-1 gene transcription and, as a consequence, PAI-1 plasma levels. Metabolic par...

journal_title：Endocrine research

authors： Zietz B,Buechler C,Drobnik W,Herfarth H,Schölmerich J,Schäffler A

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:It has been suggested that the changes in hormone levels that occur with menopause and aging are related to loss of muscle mass. However, the role of gonadotropins in this process is unknown. OBJECTIVES:To analyze the relationship between follicle-stimulating hormone (FSH) and luteinizing hormone (LH) and l...

journal_title：Endocrine research

authors： García-Martín A,Reyes-García R,García-Castro JM,Muñoz-Garach A,Escobar-Jiménez F,Muñoz-Torres M

更新日期：2013-08-01 00:00:00

abstract：:The purpose of this study was to examine the effects of exercise on anterior pituitary hormones (adrenocorticotropic hormone (ACTH), leutinizing hormone (LH) and growth hormone) as well as on cortisol at low altitude (350 meters below the sea level) and to compare these effects with those at a moderate level altitude ...

journal_title：Endocrine research

authors： Bashir N,el-Migdadi F,Hasan Z,al-Hader AA,Wezermes I,Gharaibeh M

更新日期：1996-08-01 00:00:00

abstract：:A comparative study (n = 20) of serum levels of leutinizing hormone (LH) and testosterone (T) between male trained athletes (high-school students, 16-18 years old) living in North and South Shouna in the Jordan Valley (JV), 320-360 meters below sea level, and those living in Ramtha and Irbid, 550-650 meters above sea ...

journal_title：Endocrine research

authors： Bani Hani I,El-Migdadi F,Shotar A,Abudheese R,Bashir N

更新日期：2001-02-01 00:00:00

abstract：:Neutrophils have an important role in the host defense. The elevated serum glucose levels of diabetics affect traditional host defenses such as neutrophil counts and functions. The causes of these impairments are not clear. We aimed to investigate changes of peripheral neutrophil counts and functions and their relatio...

journal_title：Endocrine research

authors： Cantürk Z,Cantürk NZ,Cetinarslan B,Erçin C,Dökmetaş S,Sencan M

更新日期：1999-08-01 00:00:00

abstract：:The enzyme, 3 beta-hydroxysteroid dehydrogenase/delta 5-4 isomerase (3 beta-HSD) is an essential element in the biosynthetic pathway for potent adrenal steroid hormones that appear to regulate maturation of many tissues in utero and are critical for homeostasis after birth. The results of prior studies are suggestive ...

journal_title：Endocrine research

authors： Parker CR Jr,Faye-Petersen O,Stankovic AK,Mason JI,Grizzle WE

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:Antithyroid drugs such as propylthiouracil (PTU) and methimazole (MMI) are common medications in Chinese patients with hyperthyroidism and PTU-induced antineutrophil cytoplasmic antibody (ANCA) positive vasculitis has been reported. The current cross-sectional study aimed to investigate the prevalence and the...

journal_title：Endocrine research

authors： Gao Y,Zhao MH,Guo XH,Xin G,Gao Y,Wang HY

更新日期：2004-05-01 00:00:00

abstract：:In order to study the role of Platelet Activating Factor (PAF) in the mechanism of parturition and connective tissue metabolism in the pregnant rat uterus, we investigated the influence of the Platelet Activating Factor Receptor Antagonist (BN 52021) on gestation duration and collagen concentration in pregnant rat ute...

journal_title：Endocrine research

authors： Bieńkiewicz A,Pajszczyk-Kieszkiewicz T,Kuś E,Dabrowski R

更新日期：1994-11-01 00:00:00

abstract：:The determination of DNA ploidy and the study of the cell cycle in adrenocortical tumoral cells could help in the distinction between benign and malignant lesions and also in the prediction of the biological behaviour of these tumors. We analysed 32 cases of adrenal tissue (8 normal adrenals--N, 12 benign adenomas--A ...

journal_title：Endocrine research

authors： Pignatelli D,Leitão D,Maia M,Schmidt F

更新日期：1998-08-01 00:00:00

abstract：:Background: Evidence has shown that low thyroid hormone levels may lead to worse prognosis including a higher mortality rate in patients with heart failure (HF). Thyroid replacement increases cardiac output and exercise performance without causing significant adverse events. The purpose of this study is to compare lev...

journal_title：Endocrine research

authors： Yang T,Ruegger M,Colavecchia AC,Sadhu A,Patham B,Tatara A

更新日期：2020-02-01 00:00:00