Technical Note: Immunohistochemical evaluation of mouse brain irradiation targeting accuracy with 3D-printed immobilization device.

abstract：PURPOSE:To reduce image noise and radiation dose in Digital Breast Tomosynthesis (DBT) reconstructions. METHODS:A retrospective study was performed on clinical data sets acquired at a normal dose with Hologic Selenia Dimensions DBT systems. The Prior Image Constrained Compressed Sensing (PICCS) algorithm was used to r...

journal_title：Medical physics

authors： Garrett J,Tang J,Zhang Y,Ruth C,Jing Z,Chen GH

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:In intensity-modulated proton therapy (IMPT), protons are used to deliver highly conformal dose distributions, targeting tumors, and sparing organs-at-risk. However, due to uncertainties in both patient setup and relative stopping power (RSP) calculation, margins are added to the treatment volume during treatme...

journal_title：Medical physics

authors： Harms J,Lei Y,Wang T,McDonald M,Ghavidel B,Stokes W,Curran WJ,Zhou J,Liu T,Yang X

更新日期：2020-09-01 00:00:00

abstract：:Electron energy spectra and angular distributions, including angular spreads, were measured using magnetic spectrometer techniques, at isocenter, for two clinical linear accelerators: one scanning beam machine, which achieves field flatness by scanning a pencil beam over the desired field at the patient plane, and one...

journal_title：Medical physics

authors： Deasy JO,Almond PR,McEllistrem MT

更新日期：1996-05-01 00:00:00

abstract：:We measured the physical imaging performance of a 41 x 41 cm2 amorphous silicon flat panel detector designed for angiographic and R&F imaging applications using methods from the emerging IEC standard for the measurement of detective quantum efficiency (DQE) in digital radiographic detectors. Measurements on 12 product...

journal_title：Medical physics

authors： Granfors PR,Aufrichtig R,Possin GE,Giambattista BW,Huang ZS,Liu J,Ma B

更新日期：2003-10-01 00:00:00

abstract：:Currently, two classes of the computational phantoms have been developed for dosimetry calculation: (1) stylized (or mathematical) and (2) voxel (or tomographic) phantoms describing human anatomy through mathematical surface equations and three-dimensional labeled voxel matrices, respectively. Mathematical surface equ...

journal_title：Medical physics

authors： Lee C,Lodwick D,Williams JL,Bolch WE

更新日期：2008-06-01 00:00:00

abstract：:In nuclear magnetic resonance (NMR) imaging by the zeugmatographic methods, there is a common and unified theoretical description. All forms of two-dimensional and three-dimensional imaging involve NMR data which trace various geometric representations, in reciprocal transform space, of the subject's spatially blurred...

journal_title：Medical physics

authors： King KF,Moran PR

更新日期：1984-01-01 00:00:00

abstract：PURPOSE:The variable resolution x-ray (VRX) CT scanner provides substantial improvement in the spatial resolution by matching the scanner's field of view (FOV) to the size of the object being imaged. Intercell x-ray cross-talk is one of the most important factors limiting the spatial resolution of the VRX detector. In ...

journal_title：Medical physics

authors： Arabi H,Asl AR,Ay MR,Zaidi H

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:Compton camera imaging (CCI) systems are currently under investigation for radiotherapy dose reconstruction and verification. The ability of such a system to provide real-time images during dose delivery will be limited by the computational speed of the image reconstruction algorithm. In this work, the authors ...

journal_title：Medical physics

authors： Mundy DW,Herman MG

更新日期：2011-01-01 00:00:00

abstract：:Recently, new imaging modalities based on the detection of weak phase perturbations effects, among which are phase contrast and diffraction imaging, have been developed by several researchers. Due to their high sensitivity to weakly absorbing details, these techniques seem to be very promising for applications in the ...

journal_title：Medical physics

authors： Olivo A,Arfelli F,Cantatore G,Longo R,Menk RH,Pani S,Prest M,Poropat P,Rigon L,Tromba G,Vallazza E,Castelli E

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:Cone beam computed tomography (CBCT) suffers from a large amount of scatter, resulting in severe scatter artifacts in the reconstructions. Recently, a new scatter correction approach, called improved primary modulator scatter estimation (iPMSE), was introduced. That approach utilizes a primary modulator that is...

journal_title：Medical physics

authors： Bier B,Berger M,Maier A,Kachelrieß M,Ritschl L,Müller K,Choi JH,Fahrig R

更新日期：2017-09-01 00:00:00

abstract：:The purpose of this work is to investigate algorithms for the delivery of intensity-modulated fields using independent collimators (IC). Two heuristic algorithms are proposed to calculate jaw-setting sequences for arbitrary 2D intensity distributions. The first algorithm is based on searching the whole intensity matri...

journal_title：Medical physics

authors： Dai JR,Hu YM

更新日期：1999-12-01 00:00:00

abstract：PURPOSE:State of the art to access radiofrequency (RF) heating near implants is computer modeling of the devices and solving Maxwell's equations for the specific setup. For a set of input parameters, a fixed result is obtained. This work presents a theoretical approach in the alternating current (ac) limit, which can p...

journal_title：Medical physics

authors： Ballweg V,Eibofner F,Graf H

更新日期：2011-10-01 00:00:00

abstract：:Computer algorithms for rotational therapy beams, in most cases, perform dose calculations by summing stored fixed beam data at finite angular steps. Such an algorithm, based on the Bentley beam model, was evaluated by comparing calculations with measured data for an 18-MV x-ray beam. Measurements were made in a speci...

journal_title：Medical physics

authors： Kurup RG,Hogstrom KR,Hwang CC

更新日期：1987-11-01 00:00:00

abstract：PURPOSE:The automated segmentation of each lung and trachea in CT scans is commonly taken as a solved problem. Indeed, existing approaches may easily fail in the presence of some abnormalities caused by a disease, trauma, or previous surgery. For robustness, we present ALTIS (implementation is available at http://lids....

journal_title：Medical physics

authors： Sousa AM,Martins SB,Falcão AX,Reis F,Bagatin E,Irion K

更新日期：2019-11-01 00:00:00

abstract：PURPOSE:A radiophotoluminescent glass rod dosimeter (RGD) has recently become commercially available. It is being increasingly used for dosimetry in radiotherapy to measure the absorbed dose including scattered low-energy photons on the body surface of a patient and for postal dosimetry audit. In this article, the dosi...

journal_title：Medical physics

authors： Kadoya N,Shimomura K,Kitou S,Shiota Y,Fujita Y,Dobashi S,Takeda K,Jingu K,Matsushita H,Namito Y,Ban S,Koyama S,Tabushi K

更新日期：2012-10-01 00:00:00

abstract：:The geometric accuracy and precision of an image-guided treatment system were assessed. Image guidance is performed using an x-ray volume imaging (XVI) system integrated with a linear accelerator and treatment planning system. Using an amorphous silicon detector and x-ray tube, volumetric computed tomography images ar...

journal_title：Medical physics

authors： Sharpe MB,Moseley DJ,Purdie TG,Islam M,Siewerdsen JH,Jaffray DA

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:Alpha-emitting radionuclides exhibit a potential advantage for cancer treatments because they release large amounts of ionizing energy over a few cell diameters (50-80 μm), causing localized, irreparable double-strand DNA breaks that lead to cell death. Radioimmunotherapy (RIT) approaches using monoclonal antib...

journal_title：Medical physics

authors： Miller BW,Frost SH,Frayo SL,Kenoyer AL,Santos E,Jones JC,Green DJ,Hamlin DK,Wilbur DS,Fisher DR,Orozco JJ,Press OW,Pagel JM,Sandmaier BM

更新日期：2015-07-01 00:00:00

abstract：PURPOSE:Transrectal ultrasound (TRUS)-guided needle biopsy is the current gold standard for prostate cancer diagnosis. However, up to 40% of prostate cancer lesions appears isoechoic on TRUS. Hence, TRUS-guided biopsy has a high false negative rate for prostate cancer diagnosis. Magnetic resonance imaging (MRI) is bett...

journal_title：Medical physics

authors： Sparks R,Bloch BN,Feleppa E,Barratt D,Moses D,Ponsky L,Madabhushi A

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To review the issues a physicist may encounter in a community hospital during the transition from film/paper charts to a paperless environment with ARIA and a TrueBeam LINAC. With a lean budget, it was necessary for the physics group to take on the project management responsibilities in order save costs. This w...

journal_title：Medical physics

authors： Chu K,Rasmussen B

更新日期：2012-06-01 00:00:00

abstract：:Multielectrode cochlear implantation is the most effective treatment for profound sensorineural hearing loss. In vivo three-dimensional 3-D localization of cochlear implant electrodes is important for modeling of the electrical field in the cochlea, design of electrode arrays, and may improve speech processor programm...

journal_title：Medical physics

authors： Yang S,Wang G,Skinner MW,Rubinstein JT,Vannier MW

更新日期：2000-04-01 00:00:00

abstract：:Breast density, the percentage of glandular breast tissue, has been identified as an important yet underutilized risk factor in the development of breast cancer. A quantitative method to measure breast density with dual energy imaging was investigated using a computer simulation model. Two configurations to measure br...

journal_title：Medical physics

authors： Ducote JL,Molloi S

更新日期：2008-12-01 00:00:00

abstract：:Radiographic image guidance has emerged as the new paradigm for patient positioning, target localization, and external beam alignment in radiotherapy. Although widely varied in modality and method, all radiographic guidance techniques have one thing in common--they can give a significant radiation dose to the patient....

journal_title：Medical physics

authors： Murphy MJ,Balter J,Balter S,BenComo JA Jr,Das IJ,Jiang SB,Ma CM,Olivera GH,Rodebaugh RF,Ruchala KJ,Shirato H,Yin FF

更新日期：2007-10-01 00:00:00

abstract：:An experiment to determine the peak of the energy spectrum of the photon beam from a Toshiba LMR-15 medical linear accelerator is described. It is found that the flattening filters removed much of the bremsstrahlung spectrum below approximately 1 MeV, resulting in a photon spectrum which peaks around 1.2 MeV. ...

journal_title：Medical physics

authors： Brownridge J,Samnick S,Stiles P,Tipton P,Veselka J,Yeh N

更新日期：1984-11-01 00:00:00

abstract：:A PTW Riga diamond detector and LiF TLDs have been evaluated for use in proton beam dosimetry by comparing results of proton beam calibration with those obtained using thimble ionization chambers. The thimble ionization chambers were calibrated in terms of exposure while the TLDs and diamond detector were calibrated i...

journal_title：Medical physics

authors： Vatnitsky S,Miller D,Siebers J,Moyers M

更新日期：1995-04-01 00:00:00

abstract：:Contemporary reconstruction methods employed for clinical helical cone-beam computed tomography (CT) are analytical (noniterative) but mathematically nonexact, i.e., the reconstructed image contains so called cone-beam artifacts, especially for higher cone angles. Besides cone artifacts, these methods also suffer from...

journal_title：Medical physics

authors： Sunnegårdh J,Danielsson PE

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:Talbot-Lau x-ray interferometry provides information about the scattering and refractive properties of an object - in addition to the object's attenuation features. Until recently, this method was ineligible for imaging human-sized objects as it is challenging to adapt Talbot-Lau interferometers (TLIs) to the r...

journal_title：Medical physics

authors： Hauke C,Bartl P,Leghissa M,Ritschl L,Sutter SM,Weber T,Zeidler J,Freudenberger J,Mertelmeier T,Radicke M,Michel T,Anton G,Meinel FG,Baehr A,Auweter S,Bondesson D,Gaass T,Dinkel J,Reiser M,Hellbach K

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To correct for the deviations of the detector response when typical radiation detectors are used under non-reference conditions, factor kNR was calculated from the known energy dependence of the detector response at photon energies from 10 keV upwards and from clinical photon spectra within a large water phanto...

journal_title：Medical physics

authors： Chofor N,Poppe B,Harder D

更新日期：2012-06-01 00:00:00

abstract：:The propagation of noise in digitized images arrived at by algebraic manipulation of two images has been investigated. The algebraic manipulations investigated were logarithmic subtraction, linear subtraction, and division of the two images. The two images were identical except for the presence of a contrast-adding co...

journal_title：Medical physics

authors： Baily NA,Rimkus D,Nalcioglu O

更新日期：1983-01-01 00:00:00

abstract：PURPOSE:Episcleral eye plaque brachytherapy has been utilized in the treatment of intra-ocular malignancies, delivering large prescription doses to the apex of the tumor. Advances in dose calculation and image guidance, via calibrated fundus images, enable localization of the tumor and determination of dose to the macu...

journal_title：Medical physics

authors： Guida K,Niermann K,Malcolm A,Sternberg P,Munn G,Coffey C

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:The lateral edge of a proton therapy beam is commonly used to achieve conformality to the treatment volume where critical structures reside close to the target. However, when treating shallow depths, the lateral edge of a pencil beam scanning (PBS) system may be broader than that of a double scattered (DS) syst...

journal_title：Medical physics

authors： Charlwood FC,Aitkenhead AH,Mackay RI

更新日期：2016-03-01 00:00:00