Abstract：
:Perceptual decisions require the transformation of raw sensory inputs into cortical representations suitable for stimulus discrimination. One of the best-known examples of this transformation involves the middle temporal area (MT) of the primate visual cortex. Area MT provides a robust representation of stimulus motion, and previous work has shown that it contributes causally to performance on motion discrimination tasks. Here we report that the strength of this contribution can be highly plastic: depending on the recent training history, pharmacological inactivation of MT can severely impair motion discrimination, or it can have little detectable influence. Further analysis of neural and behavioral data suggests that training moves the readout of motion information between MT and lower-level cortical areas. These results show that the contribution of individual brain regions to conscious perception can shift flexibly depending on sensory experience.
journal_name
Neuronjournal_title
Neuronauthors
Liu LD,Pack CCdoi
10.1016/j.neuron.2017.06.024subject
Has Abstractpub_date
2017-07-19 00:00:00pages
436-446.e3issue
2eissn
0896-6273issn
1097-4199pii
S0896-6273(17)30548-2journal_volume
95pub_type
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