Innovations and Developments in Dermatologic Non-invasive Optical Imaging and Potential Clinical Applications.

Abstract:

:Most dermatologists are aware of the benefits of dermoscopy, and a few are familiar with laser-scanning confocal microscopy. Beyond confocal, there are fully 11 different categories of optical techniques that have been applied to clinical dermatology. This article first provides a comprehensive tabular overview of all these optical diagnostic technologies and then details 4 of the lesser known innovations that are already available or still in development (laser Doppler and speckle imaging, Raman spectroscopy, multiphoton microscopy, photoacoustic tomography), with some potential applications in clinical dermatology (blood flow monitoring, skin cancer diagnosis, composition measurements in atopic dermatitis, skin rejuvenation measurement, and noninvasive sentinel lymph node assessment in melanoma). These methods present many advantages, being non-invasive, portable, and rapid. The development of optics in biological and biomedical sciences (i.e. biophotonics) requires not only deep insight into the applications but also synergistic collaboration be-tween engineers and clinicians.

journal_name

Acta Derm Venereol

authors

Tkaczyk E

doi

10.2340/00015555-2717

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

5-13

eissn

0001-5555

issn

1651-2057

journal_volume

Suppl 218

pub_type

杂志文章
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    abstract::Cell-mediated immunity in patients with verified dermatophytosis was investigated by means of skin test and lymphocyte stimulation test (LST) using purified trichophytin, prepared by the ethylene glycol method, and commercially available trichophytin. The purified trichophytin seemed to be more specific and sensitive ...

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    pub_type: 杂志文章

    doi:

    authors: Kaaman T,Petrini B,Wasserman J

    更新日期:1979-01-01 00:00:00

  • Pressing and stretching of psoriatic lesions induces their involution.

    abstract::Remission of psoriatic lesions was induced when the lesions were firmly pressed with a plastic cap held in place by an elastic bandage for 24 h or stretched with a negative pressure of 200 mmHg for 2 h. Seven out of 10 patients showed a clinical improvement of the treated psoriatic lesions. These lesions cleared withi...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:102340/0001555570176179

    authors: Takematsu H,Tagami H

    更新日期:1990-01-01 00:00:00

  • Pregnancy and porphyria cutanea tarda.

    abstract::A 31-year-old woman developed typical clinical and laboratory signs of PCT at the end of her second pregnancy coincident with the summer season. She had elevated liver function values without history of alcoholism, hepatitis or chemical liver damage. She had taken oral contraceptive only before her first pregnancy whi...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Rajka G

    更新日期:1984-01-01 00:00:00

  • Prognosis and atopic background of juvenile plantar dermatosis and gluteo-femoral eczema.

    abstract::A 10-year follow-up of patients with juvenile plantar dermatosis and gluteo-femoral eczema disclosed a worse prognosis than previously assumed, with a course in some cases protracted into adult age. The presence of atopy was established with a clinical point score system. It was found that 52% of the patients with juv...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Svensson A

    更新日期:1988-01-01 00:00:00

  • Improvement of progressive systemic sclerosis (PSS) with estriol treatment.

    abstract::Two female patients suffering from progressive systemic sclerosis (PSS) of generalized type were treated with estriol for 10 months. Although complete cure was not achieved, considerable beneficial effects were observed in these patients, but no serious side effects. Thus, skin softening was observed on all involved p...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Katayama H,Ohsawa K,Yaoita H

    更新日期:1984-01-01 00:00:00

  • Peripheral blood lymphocyte subpopulations in patients with viral warts.

    abstract::Peripheral blood T-cell subpopulations were evaluated in 32 patients affected by viral warts and in 32 unaffected individuals belonging to a control group. A significant decrease was found in total lymphocytes as well as OKT3 and OKT4 subsets among affected patients. A significant negative correlation was also found b...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Betti R,Lodi A,Masnada MC,Cattaneo M,Rosti A

    更新日期:1986-01-01 00:00:00

  • Different roles of capsaicin-sensitive and H1 histamine receptor-expressing sensory neurones in itch of mosquito allergy in mice.

    abstract::Although mosquito allergy induces the release of histamine, the itch-related response, scratching, is not effectively suppressed by blockade of H1 histamine receptors. To address this question, we examined the effects of neonatal capsaicin treatment on allergic reactions and H1 histamine receptor-expressing sensory ne...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0479

    authors: Nakano T,Andoh T,Sasaki A,Nojima H,Kuraishi Y

    更新日期:2008-01-01 00:00:00

  • Expression of CCR2 on monocytes and macrophages in chronically inflamed skin in atopic dermatitis and psoriasis.

    abstract::Monocytes form a significant component of the inflammatory reaction taking place in the skin of atopic dermatitis and psoriasis. Chemokines are pivotal in mediating the attraction of leucocytes to sites of inflammation. The CC-chemokine, monocyte chemotactic protein 1 (MCP-1/CCL2), is expressed by keratinocytes in bot...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/00015550410034444

    authors: Vestergaard C,Just H,Baumgartner Nielsen J,Thestrup-Pedersen K,Deleuran M

    更新日期:2004-01-01 00:00:00

  • Attentional Bias Towards Visual Itch and Pain Stimuli in Itch- and Pain-free Individuals?

    abstract::Itch and pain are important attention-demanding sensations that allow adaptive responses to potential bodily harm. An attentional bias towards itch and pain stimuli, i.e. preferential attention allocation towards itch- and pain-related information, has been found in healthy, as well as patient groups. However, it rema...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-3537

    authors: Becker JM,Vreijling SR,Dobbinga S,Giesbers JJJ,Evers AWM,Veldhuijzen DS,Laarhoven AIM

    更新日期:2020-07-02 00:00:00

  • The complement fixing ability of anti-basement membrane zone IgG subclass of herpes gestationis and bullous pemphigoid.

    abstract::The antibody activities and complement fixing ability of the IgG subclass antibodies of herpes gestationis (HG) and bullous pemphigoid (BP) antibodies were investigated. IgG was prepared by DEAE Affi-Gel Blue column. IgG3 and IgG 1.2.4 fractions were isolated through Protein-A Sepharose CL-4B column. In HG, neither Ig...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Suzuki M,Watanabe C,Yaoita H

    更新日期:1989-01-01 00:00:00

  • Elevated colchicine sensitivity of dermal lymphocytes in mycosis fungoides.

    abstract::Lymphocytes in chronic lymphocytic leukaemia and in other malignant lymphomas exhibit an extreme sensitivity to colchicine and are cytolysed in vitro by 10(-6) M colchicine. This characteristic can be quantified with the colchicine sensitivity index which is used for diagnostic purposes. We have demonstrated that lymp...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Sterry W,Steigleder GK,Nikolai B

    更新日期:1980-01-01 00:00:00

  • A quantitative method for the assessment of the microtopography of human skin.

    abstract::The skin relief influences the exterior aspect of the skin which is very sensitive to aging. It could also be related to the mechanical properties and structure of both dermis and stratum corneum. Consequently, quantitative measurement of the skin surface roughness would seem most useful, as it would permit a quantifi...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Makki S,Barbenel JC,Agache P

    更新日期:1979-01-01 00:00:00

  • Response of intractable skin ulcers in recessive dystrophic epidermolysis bullosa patients to an allogeneic cultured dermal substitute.

    abstract::Recessive dystrophic epidermolysis bullosa (RDEB) is an inherited skin disorder caused by mutations in the COL7A1 gene, which encodes collagen VII (COL7). Skin ulcers in RDEB patients are sometimes slow to heal. We describe here the therapeutic response of intractable skin ulcers in two patients with generalized RDEB ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0776

    authors: Natsuga K,Sawamura D,Goto M,Homma E,Goto-Ohguchi Y,Aoyagi S,Akiyama M,Kuroyanagi Y,Shimizu H

    更新日期:2010-03-01 00:00:00

  • Irritation and staining by dithranol (anthralin) and related compounds: II. Structure-activity relationships among 10-meso-substituted acyl analogues.

    abstract::Irritation and staining by dithranol and some 10-meso-substituted acyl analogues was studied with the chamber-testing technique in a series of 50 psoriasis patients. The test concentrations for dithranol, 10-acetyldithranol, 10-propionyldithranol and 10-butyryldithranol were 0.05 and 0.5%, for 10-valeryldithranol 5% a...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Mustakallio KK

    更新日期:1980-01-01 00:00:00

  • The effect of treatment on quality of life in psoriasis patients.

    abstract::Psoriasis is a chronic skin disease with substantial impact on patients' social and relational ways of living and subsequently on their quality of life. The aim of this study was to evaluate the health-related quality of life (HRQoL) of patients with moderate to severe psoriasis treated with short contact dithranol tr...

    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1080/00015550510027801

    authors: Prins M,Krabbe PF,Swinkels QO,de Boo T,van de Kerkhof PC,van der Valk PG

    更新日期:2005-01-01 00:00:00

  • Atopic dermatitis-like pre-Sézary syndrome: role of immunosuppression.

    abstract::We describe here 4 patients with Sézary syndrome masquerading as adult-onset atopic dermatitis. The patients presented with a clinical picture compatible with wide-spread atopic dermatitis and did not fulfil the criteria for Sézary syndrome (lack of lymphoadenopathy and blood involvement, skin histology without presen...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-1149

    authors: Sokołowska-Wojdyło M,Barańska-Rybak W,Cegielska A,Trzeciak M,Lugowska-Umer H,Gniadecki R

    更新日期:2011-09-01 00:00:00

  • Cryosectioning of hair follicles. An improved method using liquid nitrogen conduction freezing.

    abstract::Horizontal sectioning of scalp biopsies is especially useful in hair diseases characterized by a reduction of follicles in size or number. Horizontal sectioning using standard cryo-microtomes is hampered by the differences in cutting properties between hair follicles and fatty tissue, resulting in loss of topography. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:102340/0001555570335338

    authors: Van Baar HM,Schalkwijk J,Perret CM

    更新日期:1990-01-01 00:00:00

  • Patch testing with a textile dye mix in two concentrations - a multicentre study by the Swedish contact dermatitis research group.

    abstract:UNLABELLED:Disperse dyes, which are used for colouring synthetic textile fibres, are well-known contact sensitisers. To investigate the outcome of patch-testing with a textile dye mix (TDM) at 7 dermatology clinics in Sweden, a TDM tested at 2 concentrations was included into the baseline series during one year. The mi...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,多中心研究

    doi:10.2340/00015555-1956

    authors: Ryberg K,Bråred-Christensson J,Engfeldt M,Isaksson M,Lindberg M,Matura M,Stenberg B,Svedman C,Bruze M

    更新日期:2015-04-01 00:00:00

  • Vascular Patterns in Cutaneous Ulcerated Basal Cell Carcinoma: A Retrospective Blinded Study Including Dermoscopy.

    abstract::The aim of this retrospective study was to determine the type and prevalence of vascular patterns in the ulcerated and non-ulcerated portions of histologically proven basal cell carcinomas (BCCs) and correlate them with other dermoscopic and clinical features, including the clinically supposed diagnosis. Three authors...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-2609

    authors: Arpaia N,Filoni A,Bonamonte D,Giudice G,Fanelli M,Vestita M

    更新日期:2017-05-08 00:00:00

  • Rosacea: The Blessing of the Celts - An Approach to Pathogenesis Through Translational Research.

    abstract::Increased expression of cathelicidin antimicrobial peptide (CAMP) is related to the pathogenesis of rosacea. CAMP plays a crucial role in antimicrobial defences, such as the killing of mycobacteria. CAMP gene expression is regulated by vitamin D-dependent (VDR) and vitamin D-independent (C/EBPα) transcription factors....

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,评审

    doi:10.2340/00015555-2220

    authors: Melnik BC

    更新日期:2016-02-01 00:00:00

  • Angiokeratomas in Fabry's disease and Fordyce's disease: successful treatment with copper vapour laser.

    abstract::Two patients with multiple angiokeratomas on genitalia and thighs, one with Fabry's disease and one with Fordyce's disease, were treated with copper vapour laser light of 578 nm wavelength. The result was desirable, with destruction and disappearance of the lesions and minimal scarring and posttreatment hyper- or hypo...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555573133135

    authors: Lapins J,Emtestam L,Marcusson JA

    更新日期:1993-04-01 00:00:00

  • Recall bias in childhood atopic diseases among adults in the Odense Adolescence Cohort Study.

    abstract::Atopic dermatitis (AD) is a common disease in childhood and an important risk factor for the later development of other atopic diseases. Many publications on childhood AD use questionnaires based on information obtained in adulthood, which introduce the possibility of recall bias. In a prospective cohort study, recall...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-2128

    authors: Mortz CG,Andersen KE,Bindslev-Jensen C

    更新日期:2015-11-01 00:00:00

  • Bullous pyoderma gangrenosum in association with myeloid leukaemia.

    abstract::The case is presented of a patient with busulfan (Myleran) treated myeloid leukaemia, who developed bullous pyoderma gangrenosum. Skin symptoms appeared at the time when treatment was discontinued due to signs of bone marrow depression. The pyoderma disappeared following treatment with systemic steroid. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Cramers M

    更新日期:1976-01-01 00:00:00

  • Transfer factor in mycosis fungoides: a case report on a patient "cured".

    abstract::A report is given of the successful treatment with transfer factor as an additional therapeutic agent of a patient in the tumour stage of mycosis fungoides who had not responded to conventional treatment with nitrogen mustard, methotrexate, or grenz rays alone. Besides twelve injections of transfer factor, the patient...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Zachariae H,Grunnet E,Thestrup-Pedersen K

    更新日期:1979-01-01 00:00:00

  • Bowel bypass arthritis dermatitis syndrome: a histological and electron microscopical study.

    abstract::A case of dermal vasculitis with arthralgia after intestinal bypass surgery is reported. A 36-year-old woman developed arthralgia and skin rash, 1 year after an ileo-jejunal bypass operation was performed for overweight (130 kg). Skin biopsy showed leucocytoclastic vasculitis in the dermis. E.M. study showed clumps of...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Sandbank M,Weltfriend S,Wolf R

    更新日期:1984-01-01 00:00:00

  • Development of gastric dysfunction in dermatitis herpetiformis.

    abstract::In order to study the development of atrophic gastritis, gastric secretory function was examined by a standard pentagastrin test 24 to 78 months after a previous examination (Ex I). The study included 12 patients with dermatitis herpetiformis (DH), 6 patients with functional signs of atrophic gastritis previously, and...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Stockbrügger R,Kastrup W,Lundqvist G,Mobacken H

    更新日期:1978-01-01 00:00:00

  • Effects of Short-term Temperature Change in the Innocuous Range on Histaminergic and Non-histaminergic Acute Itch.

    abstract::While temperatures in the noxious range are well-known to inhibit acute itch, the impact of temperature in the innocuous temperature range is less well understood. We investigated the effect of alternating short-term temperature changes in the innocuous range on histamine and cowhage-induced acute itch, taking into ac...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-3077

    authors: Lewis Z,George DN,Cowdell F,Holle H

    更新日期:2019-02-01 00:00:00

  • Gestational pemphigoid: placental morphology and function.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-1370

    authors: Huilaja L,Mäkikallio K,Sormunen R,Lohi J,Hurskainen T,Tasanen K

    更新日期:2013-01-01 00:00:00

  • Cutaneous adverse drug reactions seen at a university hospital department of dermatology.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0153

    authors: Borch JE,Andersen KE,Bindslev-Jensen C

    更新日期:2006-01-01 00:00:00

  • Histamine and cutaneous nociception: histamine-induced responses in patients with atopic eczema, psoriasis and urticaria.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/000155598433458

    authors: Heyer G,Koppert W,Martus P,Handwerker HO

    更新日期:1998-03-01 00:00:00