Transcriptional Changes Associated with Long-Term Left Ventricle Volume Overload in Rats: Impact on Enzymes Related to Myocardial Energy Metabolism.

abstract：OBJECTIVE:To evaluate the efficacy and safety of docetaxel plus oxaliplatin and capecitabine (DOX) in the first line treatment of advanced gastric adenocarcinoma. METHODS:A total of 37 patients were enrolled into this study, and they received DOX regimen (docetaxel 75 mg/m² and oxaliplatin 130 mg/m² intravenous infusi...

journal_title：BioMed research international

authors： Liu Y,Ye Z,Xi W,Ma T,Shi M,Yang L,Zhu Z,Zhang J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Varicocele is associated with high levels of DNA damage in spermatozoa due to oxidative stress and elevated levels of sperm DNA fragmentation, which has been currently proposed to be an essential additional diagnostic test to be recommended for patients with clinical varicocele. The aim of this study was to ...

journal_title：BioMed research international

authors： Kadioglu TC,Aliyev E,Celtik M

更新日期：2014-01-01 00:00:00

abstract：:Anopheles gambiae is the major malaria vector in Africa. Examining the molecular basis of A. gambiae traits requires knowledge of both genetic variation and genome-wide linkage disequilibrium (LD) map of wild A. gambiae populations from malaria-endemic areas. We sequenced the genomes of nine wild A. gambiae mosquitoes...

journal_title：BioMed research international

authors： Wang X,Afrane YA,Yan G,Li J

更新日期：2015-01-01 00:00:00

abstract：:ELABELA (ELA) is considered to be implicated in the pathophysiology of preeclampsia (PE), since ELA-deficient mice exhibited PE-like symptoms and infusion of exogenous ELA normalized the gestational hypertension (GH) and proteinuria. However, no evidence show that circulating ELA is deficient in early placental develo...

journal_title：BioMed research international

authors： Ma S,Guo C,Zhang J,Long S,Tan H,You Y

更新日期：2020-09-28 00:00:00

abstract：:Visual motor integration (VMI) is a vital ability in childhood development, which is associated with the performance of many functional skills. By using the Beery Developmental Test Package and Executive Function Tasks, the present study explored the VMI development and its factors (visual perception, motor coordinati...

journal_title：BioMed research international

authors： Fang Y,Wang J,Zhang Y,Qin J

更新日期：2017-01-01 00:00:00

abstract：:The purpose of this study was to describe the first metabolic profile of human sperm cells through the application of an untargeted platform based on gas chromatography-mass spectrometry (GC-MS). Sperm cell samples from patients diagnosed with idiopathic asthenozoospermia (n = 30) and healthy subjects (n = 30) were an...

journal_title：BioMed research international

authors： Zhao K,Zhang J,Xu Z,Xu Y,Xu A,Chen W,Miao C,Liu S,Wang Z,Jia R

更新日期：2018-02-28 00:00:00

abstract：Objectives:Percutaneous coronary intervention (PCI) is the mainstay treatment for coronary artery disease but complications such as in-stent restenosis and thrombosis remain problematic. Radiofrequency balloon angioplasty (RBA) can improve lumen dimension, fusing intimal tears, and artery dissection but is associated w...

journal_title：BioMed research international

authors： Chen Q,Wang M,Shao S,Liu H,Xia X,Tse G,Yuan M,Zhang Y,Liang X,Liu T,Li G

更新日期：2018-12-23 00:00:00

abstract：:Smoldering multiple myeloma (SMM) is an asymptomatic precursor stage of multiple myeloma (MM) characterized by clonal bone marrow plasma cells (BMPC) ≥ 10% and/or M protein level ≥ 30 g/L in the absence of end organ damage. It represents an intermediate stage between monoclonal gammopathy of undetermined significance ...

journal_title：BioMed research international

authors： Gao M,Yang G,Kong Y,Wu X,Shi J

更新日期：2015-01-01 00:00:00

abstract：:A series of sulfonamide-bearing azaheterocyclic Schiff base derivatives 3(a-j) were synthesized as carbonic anhydrase inhibitors. The substituted benzene sulfonyl chlorides 1(a-d) were reacted with N2H4 to get aromatic sulfonyl hydrazides 2(a-d). The intermediate hydrazides 2(a-d) were treated with substituted aldehyd...

journal_title：BioMed research international

authors： Abas M,Rafique H,Shamas S,Roshan S,Ashraf Z,Iqbal Z,Raza H,Hassan M,Afzal K,Rizvanov AA,Asad MHHB

更新日期：2020-02-20 00:00:00

abstract：:Translocations are the most common type of structural chromosomal abnormalities. Unbalanced translocations are usually found in children who present with congenital abnormalities, developmental delay, or intellectual disability. Balanced translocations are usually found in adults who frequently present with reproducti...

journal_title：BioMed research international

authors： Paththinige CS,Sirisena ND,Kariyawasam UGIU,Dissanayake VHW

更新日期：2019-04-02 00:00:00

abstract：:Molecular imaging based personalized therapy has been a fascinating concept for individualized therapeutic strategy, which is able to attain the highest efficacy and reduce adverse effects in certain patients. Theranostics, which integrates diagnostic testing to detect molecular targets for particular therapeutic moda...

journal_title：BioMed research international

authors： Ahn BC

更新日期：2016-01-01 00:00:00

abstract：:Blood pressure is the most important, modifiable risk factor for cardiovascular diseases. Lifestyle factors and also workload are the main, potential risk factors for the development of hypertension. This study focused on the early detection of unknown hypertension by screening employees in the hotel and restaurant in...

journal_title：BioMed research international

authors： Seibt R,Hunger B,Stieler L,Stoll R,Kreuzfeld S

更新日期：2018-04-08 00:00:00

abstract：:It has been reported that many modifications occur with the increase of oxidative stress during storage in erythrocytes. In order to delay these negative changes, we evaluated whether the addition of substances likely to protect antioxidant capacity in stored blood would be useful. Therefore, we investigated the effec...

journal_title：BioMed research international

authors： Huyut Z,Şekeroğlu MR,Balahoroğlu R,Karakoyun T,Çokluk E

更新日期：2016-01-01 00:00:00

abstract：:Breast cancer is the most frequently occurring disease among women worldwide. The early stage of breast cancer identification is the key challenge in cancer control and prevention procedures. Although gene expression profiling helps to understand the molecular mechanism of diseases or disorder in the living system, ge...

journal_title：BioMed research international

authors： Abdullah Al-Dhabi N,Srigopalram S,Ilavenil S,Kim YO,Agastian P,Baaru R,Balamurugan K,Choi KC,Valan Arasu M

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Cerebral white matter hyperintensity (WMH) with magnetic resonance imaging (MRI) has a potential for predicting cognitive impairment. Serum polyunsaturated fatty acid (PUFA) levels are important for evaluating the extent of atherosclerosis. We investigated whether abnormal PUFA levels affected WMH grading and...

journal_title：BioMed research international

authors： Suwa M,Yamaguchi S,Komori T,Kajimoto S,Kino M

更新日期：2015-01-01 00:00:00

abstract：:Modified poly(aspartic acid)/poly(vinyl alcohol) interpenetrating polymer network (KPAsp/PVA IPN) hydrogel for drug controlled release was synthesized by a simple one-step method in aqueous system using poly(aspartic acid) grafting 3-aminopropyltriethoxysilane (KH-550) and poly(vinyl alcohol) (PVA) as materials. The h...

journal_title：BioMed research international

authors： Lu J,Li Y,Hu D,Chen X,Liu Y,Wang L,Zhao Y

更新日期：2015-01-01 00:00:00

abstract：:Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis in children, and renal involvement (HSP nephritis, HSPN) is a severe manifestation. HSPN is histologically classified by the International Study of Kidney Disease in Children (ISKDC) based on mesangial hypercellularity and the extent of glomerular c...

journal_title：BioMed research international

authors： Kim J,Choi SE,Lee KH,Jeong HJ,Shin JI,Lim BJ

更新日期：2019-01-20 00:00:00

abstract：:Mouse lines selected for maximal (AIRmax) or minimal acute inflammatory reaction (AIRmin) were used to characterize the immune response and the influence of genetic background during pristane-induced arthritis (PIA). Susceptible AIRmax mice demonstrated exacerbated cellular profiles during PIA, with intense infiltrati...

journal_title：BioMed research international

authors： Correa MA,Borrego A,Jensen JR,Cabrera WHK,Barros M,Katz ISS,Canhamero T,Spadafora-Ferreira M,Fernandes JG,Starobinas N,Ribeiro OG,Ibañez OM,De Franco M

更新日期：2018-10-08 00:00:00

abstract：AIM:Cardiac rehabilitation (CR) is an important part of heart failure (HF) treatment. The aim of this paper was to evaluate if thoracic fluid content (TFC) measured by impedance cardiography (ICG) is a useful parameter for predicting the outcome of CR. METHODS:Fifty HF patients underwent clinical and noninvasive haemo...

journal_title：BioMed research international

authors： Gielerak G,Krzesiński P,Piotrowicz E,Piotrowicz R

更新日期：2013-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/7268308.]. ...

journal_title：BioMed research international

authors： Lin JA,Blanco R,Shibata Y,Nakamoto T,Lin KH

更新日期：2018-07-05 00:00:00

abstract：:Among uterine structural abnormalities, myomas and adenomyosis represent two distinct, though frequently coexistent entities, with a remarkable prevalence in women of reproductive age. Various mechanisms have been proposed to explain the impact of each of them on reproductive outcome. In respect to myomas, current evi...

journal_title：BioMed research international

authors： Vlahos NF,Theodoridis TD,Partsinevelos GA

更新日期：2017-01-01 00:00:00

abstract：:Osteoarthritis (OA) is a chronic degenerative joint disease, where chondrocyte apoptosis is responsible for cartilage degeneration. Bax is a well-known proapoptotic protein of the Bcl-2 family, involved in a large number of physiological and pathological processes. However, the regulation mechanisms of Bax underlying ...

journal_title：BioMed research international

authors： Miao G,Zang X,Hou H,Sun H,Wang L,Zhang T,Tan Y,Liu W,Ye P,Gao L,Zha Z

更新日期：2019-03-12 00:00:00

abstract：:Mitochondrial uncoupling protein 2 (UCP2) is suggested to have a role in the development of nonalcoholic steatohepatitis (NASH). However, the mechanism remains unclear. Autophagy is an important mediator of many pathological responses. This study aims to investigate the relationship between UCP2 and hepatoma cells aut...

journal_title：BioMed research international

authors： Lou J,Wang Y,Wang X,Jiang Y

更新日期：2014-01-01 00:00:00

abstract：:T. reesei is an efficient cellulase producer and biomass degrader. To improve xylitol production in Trichoderma reesei strains by genetic engineering, two approaches were used in this study. First, the presumptive D-xylulokinase gene in T. reesei (xyiH), which has high homology to known fungi D-xylulokinase genes, was...

journal_title：BioMed research international

authors： Hong Y,Dashtban M,Kepka G,Chen S,Qin W

更新日期：2014-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/6353510.]. ...

journal_title：BioMed research international

authors： Skjerdal T,Gefferth A,Spajic M,Estanga EG,De Cesare A,Vitali S,Pasquali F,Bovo F,Manfreda G,Mancusi R,Trevisiani M,Tessema GT,Fagereng T,Moen LH,Lyshaug L,Koidis A,Delgado-Pando G,Stratakos AC,Boeri M,From C,Syed

更新日期：2018-09-26 00:00:00

abstract：:Elevated levels of resistin and epidermal growth factor receptor (EGFR) facilitate the development of breast cancer, although there are no reports of any correlation between these proteins. This study analyzed 392 human breast cancer tissue specimens and 42 samples of adjacent normal tissue. Rates of positive and stro...

journal_title：BioMed research international

authors： Zeng Y,Tang CH,Wang Y,Lu HJ,Huang BF,Wang Q,Shao JK,Jin LL,Wang CQ,Teng LS

更新日期：2020-11-28 00:00:00

abstract：:Myopia is the most common ocular abnormality. Its high and growing prevalence has contributed to a recent surge in surgical interest in the disorder, since retinal detachment in eyes with high myopia differs from that in emmetropic eyes or eyes with low myopia. The myopic eye, because of its specific anatomy, poses sp...

journal_title：BioMed research international

authors： Semeraro F,Morescalchi F,Russo A,Romano MR,Costagliola C

更新日期：2014-01-01 00:00:00

abstract：:This study applies the environmental Kuznets curve to test the relationship between the regional economic growth and the different types of agricultural nonpoint source pollution loads in the Ningxia Yellow River irrigation area by using the Johnes export coefficient method. Results show that the pollution load genera...

journal_title：BioMed research international

authors： Mao C,Zhai N,Yang J,Feng Y,Cao Y,Han X,Ren G,Yang G,Meng QX

更新日期：2013-01-01 00:00:00

abstract：:Heart rate variability is a physiological feature indicating the influence of the autonomic nervous system on the heart rate. Association of the reduced heart rate variability due to myocardial infarction and the increased postinfarction mortality was first described more than thirty years ago. Many studies have unequ...

journal_title：BioMed research international

authors： Lakusic N,Mahovic D,Kruzliak P,Cerkez Habek J,Novak M,Cerovec D

更新日期：2015-01-01 00:00:00

abstract：:Macrophages play a key role in immunity. In this review, we consider the traditional notion of macrophage plasticity, data that do not fit into existing concepts, and a hypothesis for existence of a new switch macrophage phenotype. Depending on the microenvironment, macrophages can reprogram their phenotype toward the...

journal_title：BioMed research international

authors： Malyshev I,Malyshev Y

更新日期：2015-01-01 00:00:00