Anti-Ebola therapies based on monoclonal antibodies: current state and challenges ahead.

abstract：:Butanol is a precursor of many industrial chemicals, and a fuel that is more energetic, safer and easier to handle than ethanol. Fermentative biobutanol can be produced using renewable carbon sources such as agro-industrial residues and lignocellulosic biomass. Solventogenic clostridia are known as the most preeminent...

journal_title：Critical reviews in biotechnology

authors： Jiménez-Bonilla P,Wang Y

更新日期：2018-05-01 00:00:00

abstract：:Briskly evolving phytopathogens are dire threats to our food supplies and threaten global food security. From the recent advances made toward high-throughput sequencing technologies, understanding of pathogenesis and effector biology, and plant innate immunity, translation of these means into new control tools is bein...

journal_title：Critical reviews in biotechnology

authors： Nejat N,Rookes J,Mantri NL,Cahill DM

更新日期：2017-03-01 00:00:00

abstract：:A large number of rice agronomic traits are complex, multi factorial and polygenic. As the mechanisms and genes determining grain size and yield are largely unknown, the identification of regulatory genes related to grain development remains a preeminent approach in rice genetic studies and breeding programs. Genes re...

journal_title：Critical reviews in biotechnology

authors： Azizi P,Osman M,Hanafi MM,Sahebi M,Rafii MY,Taheri S,Harikrishna JA,Tarinejad AR,Mat Sharani S,Yusuf MN

更新日期：2019-11-01 00:00:00

abstract：:Chitosan, copolymer of glucosamine and N-acetyl glucosamine is mainly derived from chitin, which is present in cell walls of crustaceans and some other microorganisms, such as fungi. Chitosan is emerging as an important biopolymer having a broad range of applications in different fields. On a commercial scale, chitosa...

journal_title：Critical reviews in biotechnology

authors： Dhillon GS,Kaur S,Brar SK,Verma M

更新日期：2013-12-01 00:00:00

abstract：:Recombinant DNA technology enables the creation of well-defined alterations in the genetic material of an organism. Methods to manipulate recombinant DNA in the filamentous fungi (a group of microorganisms that includes species of academic as well as commercial interest) have recently been developed. This has been the...

journal_title：Critical reviews in biotechnology

authors： Rambosek J,Leach J

更新日期：1987-01-01 00:00:00

abstract：:Semisynthetic cephalosporins are important antibacterials in clinical practice. Semisynthetic cephalosporins are manufactured by derivatizing 7-aminocephalosporanic acid (7-ACA) and its desacetylated form. Microbial enzymes such as D-amino acid oxidase, glutaryl-7-ACA acylase and cephalosporin esterase are being used ...

journal_title：Critical reviews in biotechnology

authors： Sonawane VC

更新日期：2006-04-01 00:00:00

abstract：:The role of selenium (Se) in human health and diseases has been discussed in detail in several recent reviews, with the main conclusion being that selenium deficiency is recognised as a global problem which urgently needs resolution. Since selenium content in plant-based food depends on its availability from soil, the...

journal_title：Critical reviews in biotechnology

authors： Fisinin VI,Papazyan TT,Surai PF

更新日期：2009-01-01 00:00:00

abstract：:Starting with a brief history of solid-state fermentation (SSF), major aspects of SSF are reviewed, which include factors affecting SSF, biomass, fermentors, modeling, industrial microbial enzymes, organic acids, secondary metabolites, and bioremediation. Physico-chemical and environmental factors such as inoculum typ...

journal_title：Critical reviews in biotechnology

authors： Krishna C

更新日期：2005-01-01 00:00:00

abstract：:Experimental design is a form of process analysis in which certain factors are selected to obtain the desired responses of interest. It may also be used for the determination of the effects of various independent factors on a dependent factor. The bioengineering discipline includes many different areas of scientific i...

journal_title：Critical reviews in biotechnology

authors： Keskin Gündoğdu T,Deniz İ,Çalışkan G,Şahin ES,Azbar N

更新日期：2016-01-01 00:00:00

abstract：:In recent years, foods that contain omega-3 lipids have emerged as important promoters of human health. These lipids are essential for the functional development of the brain and retina, and reduction of the risk of cardiovascular and Alzheimer's diseases. The global market for omega-3 production, particularly docosah...

journal_title：Critical reviews in biotechnology

authors： Finco AMO,Mamani LDG,Carvalho JC,de Melo Pereira GV,Thomaz-Soccol V,Soccol CR

更新日期：2017-08-01 00:00:00

abstract：:In recent years, the advances in microbiology show that biofilms are structurally complex, dynamic and adaptable systems including attributes of multicellular organisms and miscellaneous ecosystems. One may distinguish between beneficial and harmful biofilms appearing in daily life as well as various industrial proces...

journal_title：Critical reviews in biotechnology

authors： Böl M,Ehret AE,Bolea Albero A,Hellriegel J,Krull R

更新日期：2013-06-01 00:00:00

abstract：:Microorganisms have the tendency to accumulate at interfaces through the release of extracellular polymeric substances to form aggregates such as films or flocs. This physical association leads to different modes of interactions among cells and the subsequent development of functionally and metabolically diverse conso...

journal_title：Critical reviews in biotechnology

authors： Srivastava A,Seo SH,Ko SR,Ahn CY,Oh HM

更新日期：2018-12-01 00:00:00

abstract：:The Vitamin K series, particularly menaquinone, have been attracting research attention, due to the potential in reducing both osteoporosis and cardiovascular diseases. This review provides an overview of the types of vitamin K and their health benefits. This is followed by a critical review of the various biotechnolo...

journal_title：Critical reviews in biotechnology

authors： Berenjian A,Mahanama R,Kavanagh J,Dehghani F

更新日期：2015-06-01 00:00:00

abstract：:Global gel-free proteomic analysis by mass spectrometry has been widely used as an important tool for exploring complex biological systems at the whole genome level. Simultaneous analysis of a large number of protein species is a complicated and challenging task. The challenges exist throughout all stages of a global ...

journal_title：Critical reviews in biotechnology

authors： Nie L,Wu G,Zhang W

更新日期：2008-01-01 00:00:00

abstract：:Filamentous fungi comprise an abundance of gene clusters that encode high-value metabolites, whereas affluent gene clusters remain silent during laboratory conditions. Complex cellular metabolism further limits these metabolite yields. Therefore, diverse strategies such as genetic engineering and chemical mutagenesis ...

journal_title：Critical reviews in biotechnology

authors： Deng H,Bai Y,Fan TP,Zheng X,Cai Y

更新日期：2020-03-01 00:00:00

abstract：:Innovation holds the potential for economic prosperity. Biotechnology (BT) has proved to be a viable vehicle for the development and utilization of technologies, which has brought not only advances to society, but also career opportunities to nation-states that have enabling conditions. In this review, we assess the c...

journal_title：Critical reviews in biotechnology

authors： Dettenhofer M,Ondrejovič M,Slavica A,Kurtanjek Ž,Tapaloaga D,Rodian Tapaloaga P,Kapur Pojskić L,Durmić-Pašić A,Begović J,Nedović V,Dundar M,Gartland KMA,Miertuš S

更新日期：2019-02-01 00:00:00

abstract：:The beneficial effects of endophytes on plant growth are important for agricultural ecosystems because they reduce the need for fertilizers and decrease soil and water pollution while compensating for environmental perturbations. Endophytic fungi are a novel source of bioactive secondary metabolites; moreover, recentl...

journal_title：Critical reviews in biotechnology

authors： Khan AL,Hussain J,Al-Harrasi A,Al-Rawahi A,Lee IJ

更新日期：2015-03-01 00:00:00

abstract：:Human body harbors diverse microbes, the main components include bacteria, eukaryotes and viruses. Emerging evidences show that the human microbiota is intrinsically linked with overall health. The development of next-generation sequencing provides an unprecedented opportunity to investigate the complex microbial comm...

journal_title：Critical reviews in biotechnology

authors： Xu X,Wang Z,Zhang X

更新日期：2015-03-01 00:00:00

abstract：:Proteases have a broad range of applications in industrial processes and products and are representative of most worldwide enzyme sales. The genus Bacillus is probably the most important bacterial source of proteases and is capable of producing high yields of neutral and alkaline proteolytic enzymes with remarkable pr...

journal_title：Critical reviews in biotechnology

authors： Contesini FJ,Melo RR,Sato HH

更新日期：2018-05-01 00:00:00

abstract：:Second generation biofuel production depends on lignocellulosic (LC) biomass transformation into simple sugars and their subsequent fermentation into alcohols. However, the main obstacle in this process is the efficient breakdown of the recalcitrant cellulose to sugar monomers. Hence, efficient feedstock pretreatment ...

journal_title：Critical reviews in biotechnology

authors： Portillo Mdel C,Saadeddin A

更新日期：2015-01-01 00:00:00

abstract：:Phytoremediation uses plants and associated microbes to remove pollutants from the environment and is considered a promising bioremediation method. Compared with well-described single contaminant treatments, the number of studies reporting phytoremediation of soil mixed pollutants has increased recently. Endophytes, i...

journal_title：Critical reviews in biotechnology

authors： He W,Megharaj M,Wu CY,Subashchandrabose SR,Dai CC

更新日期：2020-02-01 00:00:00

abstract：:Vitamin C (L-ascorbic acid; AsA) is the major soluble antioxidant found in plants and is also an essential component of human nutrition. Although numerous biotechnological methods have been exploited to increase its yield, pressures such as commercial competition and environmental concerns make it urgent to find a new...

journal_title：Critical reviews in biotechnology

authors： Zhang L,Wang Z,Xia Y,Kai G,Chen W,Tang K

更新日期：2007-07-01 00:00:00

abstract：:Mushrooms have become increasingly important as a reliable food source. They have also been recognized as an important source of bioactive compounds of high nutritional and medicinal values. The nucleobases, nucleosides and nucleotides found in mushrooms play important roles in the regulation of various physiological ...

journal_title：Critical reviews in biotechnology

authors： Phan CW,Wang JK,Cheah SC,Naidu M,David P,Sabaratnam V

更新日期：2018-08-01 00:00:00

abstract：:Corynebacterium glutamicum, a Gram-positive bacterium, has been widely used for the industrial production of amino acids, such as glutamate and lysine, for decades. Due to several characteristics - its ability to secrete properly folded and functional target proteins into culture broth, its low levels of endogenous ex...

journal_title：Critical reviews in biotechnology

authors： Liu X,Zhang W,Zhao Z,Dai X,Yang Y,Bai Z

更新日期：2017-06-01 00:00:00

abstract：:Filamentous fungi play an important role not only in the bio-manufacturing of value-added products, but also in bioenergy and environmental research. The bioprocess manipulation of filamentous fungi is more difficult than that of other microbial species because of their different pellet morphologies and the presence o...

journal_title：Critical reviews in biotechnology

authors： Zhang J,Zhang J

更新日期：2016-12-01 00:00:00

abstract：:Cancer is a clinical situation caused by uncontrolled cell division and is responsible for a large number of deaths worldwide. Colchicine is a classical antimitotic, tubulin-binding agent (TBA) which is being explored for its antitumor activities, although its tubulin-binding ability leads to some toxicity toward norm...

journal_title：Critical reviews in biotechnology

authors： Dubey KK,Kumar P,Labrou NE,Shukla P

更新日期：2017-12-01 00:00:00

abstract：:Affinity tags are vital tools for the production of high-throughput recombinant proteins. Several affinity tags, such as the hexahistidine tag, maltose-binding protein, streptavidin-binding peptide tag, calmodulin-binding peptide, c-Myc tag, glutathione S-transferase and FLAG tag, have been introduced for recombinant ...

journal_title：Critical reviews in biotechnology

authors： Soleimanpour S,Hassannia T,Motiee M,Amini AA,Rezaee SA

更新日期：2017-05-01 00:00:00

abstract：:Microbial bio-transformations of the essential trace element selenium are now recognized to occur among a wide variety of microorganisms. These transformations are used to convert this element into its assimilated form of selenocysteine, which is at the active center of a number of key enzymes, and to produce selenium...

journal_title：Critical reviews in biotechnology

authors： Ojeda JJ,Merroun ML,Tugarova AV,Lampis S,Kamnev AA,Gardiner PHE

更新日期：2020-12-01 00:00:00

abstract：:Small RNAs (sRNA) are reported to play pivotal roles in the epigenetic and post-transcriptional regulation of gene expression during growth, development, and stress response in plants. Recently, the involvement of two different classes of sRNAs namely, miRNAs (microRNAs), and siRNAs (small interfering RNAs) in biotic ...

journal_title：Critical reviews in biotechnology

authors： Prasad A,Sharma N,Muthamilarasan M,Rana S,Prasad M

更新日期：2019-06-01 00:00:00

abstract：:Lactic acid, an anaerobic product of glycolysis, can be theoretically produced by synthetic route; however, it is commercially produced by homo-fermentative batch mode of operations. Factors affecting its production and strategies improving it are considered while devising an optimized protocol. Although a hetero-ferm...

journal_title：Critical reviews in biotechnology

authors： Yadav AK,Chaudhari AB,Kothari RM

更新日期：2011-03-01 00:00:00