Correlation between the protein expression of A-kinase anchor protein 95, cyclin D3 and AKT and pathological indicators in lung cancer tissues.

abstract：:Effects of antithrombotic agents on the bleeding risk after transurethral resection of the prostate (TURP) were assessed in patients with benign prostatic hyperplasia (BPH). Controlled clinical trials on the effects of perioperative anticoagulant therapy on postoperative bleeding in BPH patients published during Janua...

journal_title：Experimental and therapeutic medicine

authors： He Q,Yu Y,Gao F

更新日期：2020-10-01 00:00:00

abstract：:Giant aneurysm of the posterior circulation is associated with a higher risk of rupture compared with that of the anterior circulation. Furthermore, surgical clipping and interventional embolization for giant aneurysm of the posterior circulation are more difficult and complex to perform. The present study reported on...

journal_title：Experimental and therapeutic medicine

authors： Zhang CL,Shi ZH,Yan ZZ,Ding CL,Cao JM,Wang YH,Zhang P

更新日期：2021-01-01 00:00:00

abstract：:The binary toxin Clostridium difficile transferase (CDT) is frequently observed in C. difficile strains and is associated with an increased severity of C. difficile infection. CDT-producing C. difficile infections cause higher fatality rates than infections with CDT negative isolates. Thus, the rapid and accurate iden...

journal_title：Experimental and therapeutic medicine

authors： Yu L,Li H,Zhao X,Wang X,Wei X,Lin W,Li P,Cui L,Yuan J

更新日期：2017-11-01 00:00:00

abstract：:The aim of the present study was to examine whether the expression of focal adhesion kinase (FAK) is altered in the eutopic endometrium of female patients with adenomyosis, as compared with that of females without adenomyosis. The expression of FAK was assessed by immunohistochemical, western blot and reverse transcri...

journal_title：Experimental and therapeutic medicine

authors： Mu L,Chen W,Ma Y,Zheng W

更新日期：2015-11-01 00:00:00

abstract：:Pancreatic cancer is one of the most lethal types of cancer, and curative resection is only applicable to potentially limited cases due to early metastasis and local invasion. This study reports the influence of CXCL12 and its receptor CXCR4 on the progression of pancreatic cancer and highlights the correlation betwee...

journal_title：Experimental and therapeutic medicine

authors： Zhong W,Chen W,Zhang D,Sun J,Li Y,Zhang J,Gao Y,Zhou W,Li S

更新日期：2012-09-01 00:00:00

abstract：:Ovarian cancer is a highly prevalent cancer among women. Recent studies have indicated that microRNAs (miRs) may serve important roles in the pathogenesis of ovarian cancer. miR-519a was observed to be downregulated in tissue samples of patients with ovarian cancer; however, its role in ovarian cancer requires further...

journal_title：Experimental and therapeutic medicine

authors： Tian F,Jia L,Chu Z,Han H,Zhang Y,Cai J

更新日期：2018-02-01 00:00:00

abstract：:Lipid peroxidation is associated with several metabolic diseases. Lipid peroxidation causes cellular damage through reactive aldehyde species such as 4-hydroxyonenal (4-HNE). The exact mechanism(s) by which 4-HNE causes damage in the intravascular compartment is not yet exactly understood. Using an in vitro system, th...

journal_title：Experimental and therapeutic medicine

authors： Mustafa AG,Alfaqih MA,Al-Shboul O

更新日期：2018-09-01 00:00:00

abstract：:One of the most prevalent diseases affecting humans are those which affect the oral cavity. Several diseases can affect the mouth, such as oral cancer, dental caries, Lichen Planus and, of course, periodontal disease with its variants. This review discusses gingivitis, periodontitis and peri-implantitis with a brief f...

journal_title：Experimental and therapeutic medicine

authors： Mann J,Bernstein Y,Findler M

更新日期：2020-02-01 00:00:00

abstract：:The main function of adipocyte fatty acid-binding protein (A-FABP) is to regulate fatty acid metabolism as its molecular chaperone. The clinical significance of A-FABP in hypoxic-ischemic brain damage (HIBD) neonates is not yet clear. Free fatty acid (FFA) in cerebral cortex increases along with hypoxia ischemia degre...

journal_title：Experimental and therapeutic medicine

authors： Li M,Jiang L,Zhang H,Wang D,Zhang M,Zhang L

更新日期：2016-08-01 00:00:00

abstract：:This study was designed to assess the relationship between changes in peripheral inflammatory factors of patients complicated with non-alcoholic fatty liver disease (NAFLD) undergoing coronary artery bypass grafting (CABG) before and after operation, and their prognosis. A total of 68 patients with stable angina pecto...

journal_title：Experimental and therapeutic medicine

authors： Wang L,Li Y,Gong X

更新日期：2018-01-01 00:00:00

abstract：:The effects of atrial fibrillation on complications and prognosis of patients receiving emergency percutaneous coronary intervention after acute myocardial infarction (AMI) were investigated. Eighty AMI patients treated with interventional vascular recanalization in the Affiliated Hospital of Weifang Medical Universit...

journal_title：Experimental and therapeutic medicine

authors： Zhang Y,Zhang L,Zheng H,Chen H

更新日期：2018-10-01 00:00:00

abstract：:Uterine cervical adenocarcinoma has a poor clinical prognosis when compared with squamous cell carcinoma. Therefore, the development of new treatment strategies for uterine cervical adenocarcinoma is necessary. Src is a proto-oncogene that is important in cancer progression. Dasatinib is a Src inhibitor that has been ...

journal_title：Experimental and therapeutic medicine

authors： Takiguchi E,Nishimura M,Mineda A,Kawakita T,Abe A,Irahara M

更新日期：2017-11-01 00:00:00

abstract：:The effectiveness of therapy combining dihydroartemisinin (DHA) and small interfering RNA targeting Notch1 (siNotch1) in T-cell lymphoma remains unknown. The present study explored the potential and possible mechanisms of combined dihydroarteminin, and siNotch1 therapy for T-cell lymphoma. It was demonstrated that the...

journal_title：Experimental and therapeutic medicine

authors： Huo L,Wei W,Wu S,Zhao X,Zhao C,Zhao H,Sun L

更新日期：2018-03-01 00:00:00

abstract：:Different tacrolimus (TAC) population pharmacokinetic (PPK) models have been established in various pediatric disease populations. However, a TAC PPK model for pediatric refractory nephrotic syndrome (PRNS) has not been well characterized. The current study aimed to establish a TAC PPK model in Chinese PRNS and provid...

journal_title：Experimental and therapeutic medicine

authors： Wang D,Lu J,Li Q,Li Z

更新日期：2019-05-01 00:00:00

abstract：:Stereotactic body radiation therapy (SBRT) plays an important role in the treatment of early stage non-small cell lung cancer (NSCLC), particularly when patients are unable to tolerate surgical resection due to comorbid conditions or are unwilling to undergo surgery. High rates of local tumor control that may rival th...

journal_title：Experimental and therapeutic medicine

authors： Yang G,Li M,Wang Y,Wang Y,Liu X

更新日期：2013-09-01 00:00:00

abstract：:To exploit a cross passive immunotherapy for enterovirus-induced hand-foot-and-mouth disease (HFMD), the cross antiviral activity of a neutralizing antibody against enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) was investigated in vitro. White Leghorn specific-pathogen-free chickens were immunized with EV71 ant...

journal_title：Experimental and therapeutic medicine

authors： Gao E,Wu S,Xu Q,Zeng Y,Tan N,He S,Yang Y,Wei J

更新日期：2019-07-01 00:00:00

abstract：:The present study aimed to systematically evaluate the effectiveness of single-incision laparoscopic surgery (SILS), conventional laparoscopic appendectomy (CLA) and open appendectomy (OA) for the treatment of acute appendicitis. PubMed and Embase databases were systematically searched to identify relevant studies com...

journal_title：Experimental and therapeutic medicine

authors： Feng J,Cui N,Wang Z,Duan J

更新日期：2017-12-01 00:00:00

abstract：:The aim of the present study was to isolate, culture and characterize sheep metanephric mesenchymal stem cells (MMSCs). The MMSCs were isolated from the kidney tissue of six-week-old sheep fetus. This study investigated whether primary MMSCs could be grown for 26 passages and expressed Oct-4, which is involved in the ...

journal_title：Experimental and therapeutic medicine

authors： Ji M,Bai C,Li L,Fan Y,Ma C,Li X,Guan W

更新日期：2016-12-01 00:00:00

abstract：:Uterine leiomyoma is the most common benign tumor type of the female reproductive tract. Despite its high prevalence, the exact pathogenesis of the benign tumor remains unknown. In the present study, the effects of di-(2-ethylhexyl) phthalate (DEHP) on the proliferation and apoptosis rates and expression of inflammato...

journal_title：Experimental and therapeutic medicine

authors： Kim JH

更新日期：2018-06-01 00:00:00

abstract：:To investigate the pharmacological mechanism of Guizhi Fuling Wan (GFW) in the treatment of uterine fibroids, a network pharmacology approach was used. Information on GFW compounds was collected from traditional Chinese medicine (TCM) databases, and input into PharmMapper to identify the compound targets. Genes associ...

journal_title：Experimental and therapeutic medicine

authors： Zeng L,Yang K,Liu H,Zhang G

更新日期：2017-11-01 00:00:00

abstract：:Peptide P7 specifically binds with basic fibroblast growth factor (bFGF) to inhibit the proliferation and invasion of numerous types of cancer cell. However, this effect has remained to be demonstrated in ovarian cancer-derived cell lines. In the present study, the protein P7 was used treat bFGF-stimulated SKOV3 epith...

journal_title：Experimental and therapeutic medicine

authors： Chen Q,Yang Z,Chen X,Shu L,Qu W

更新日期：2019-04-01 00:00:00

abstract：:Rhubarb has been used as an evacuant for thousands of years. However, recent research has indicated that rhubarb inhibits inflammation and protects organ function. In the current study, the use of rhubarb was investigated in patients with intra-abdominal hypertension (IAH). Specifically, its dual role in attenuating l...

journal_title：Experimental and therapeutic medicine

authors： Wan B,Zhang H,Yin J,Fu H,Chen Y,Yang L,Liu D,Lv T,Song Y

更新日期：2017-07-01 00:00:00

abstract：:The curative effect of minimally invasive surgery on palmar and foot hyperhidrosis and its influence on serum-related cytokines and immunoglobulins were investigated. Seventy-six patients with palmar and foot hyperhidrosis admitted to Yunnan University Hospital from August 2014 to July 2016 were selected and randomly ...

journal_title：Experimental and therapeutic medicine

authors： Li WX,Li YK,Lin HT

更新日期：2018-04-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic disease of connective tissue caused by intolerance to self-antigens. Regulatory T cells (Tregs) are key players in maintaining autotolerance through a variety of suppressor mechanisms. RA is generally believed to develop due to disorders in Tregs; however, there is no consensus o...

journal_title：Experimental and therapeutic medicine

authors： Shevyrev D,Tereshchenko V,Kozlov V,Sizikov A,Chumasova O,Koksharova V

更新日期：2021-03-01 00:00:00

abstract：:The diaphragm is an important respiratory organ. The aim of this study was to quantitatively evaluate the longitudinal deformation of the right hemidiaphragm in normal subjects using two-dimensional strain ultrasound speckle tracking. Twenty-one healthy subjects were enrolled in this study. GE Healthcare Vivid E9 equi...

journal_title：Experimental and therapeutic medicine

authors： Ye X,Xiao H,Bai W,Liang Y,Chen M,Zhang S

更新日期：2013-08-01 00:00:00

abstract：:The present study examined the effectiveness of the method of inversing the distal clavicle anatomic locking plate to treat medial-end clavicle fractures. This involved retrospectively analyzing six cases of medial-end clavicle fractures treated using the method of inversing the distal clavicle anatomic locking plate ...

journal_title：Experimental and therapeutic medicine

authors： Xie WP,Zhang YK,Chen YH,Wang SL,Xu HH,Bi RX

更新日期：2018-12-01 00:00:00

abstract：:Cancer antigen 125 (CA125), encoded by the mucin 16 cell surface associated (MUC16) gene, has been widely used as a biomarker for ovarian cancer (OC) screening. However, it has yet to be elucidated as to why its levels increase with tumor progression as well as with certain other non-malignant conditions. Based on our...

journal_title：Experimental and therapeutic medicine

authors： Liu J,Li L,Luo N,Liu Q,Liu L,Chen D,Cheng Z,Xi X

更新日期：2021-02-01 00:00:00

abstract：:Vascular calcification (VC) caused by chronic kidney disease (CKD)-mineral and bone disorder is a common complication of CKD. Recent studies have demonstrated that menaquinone-4 (MK-4) is negativly associated with VC in patients with CKD. Furthermore, we have previously shown that runt-related transcription factor 2 (...

journal_title：Experimental and therapeutic medicine

authors： Cui L,Xu J,Zhang J,Zhang M,Zhang S,Bai Y

更新日期：2018-10-01 00:00:00

abstract：:17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) is a water soluble, semisynthetic derivative of endotoxin that has anticancer effects. The aim of the present study was to determine whether 17-DMAG enhances the apoptosis of lymphoma cells in diffuse large B-cell lymphoma. Apoptosis was induced in SU-DHL-4...

journal_title：Experimental and therapeutic medicine

authors： Li JJ,Zhang JJ,Wang X,Sun ZM

更新日期：2017-10-01 00:00:00

abstract：:The aim of the present study was to investigate the mucus secretion status of mature goblet cells following the application of mitomycin-C (MMC) in ileal neobladder rat models. Bladder substitution models were established in Sprague Dawley rats, which had been divided into five groups, namely the control (sham), norma...

journal_title：Experimental and therapeutic medicine

authors： Fan W,Yu Y,Shu J,Ming H,Li W,Fan Z

更新日期：2015-08-01 00:00:00