Transarterial embolization for pelvic hematoma following laparoscopic radical prostatectomy: A case report and review of the literature.

abstract：:Notch signaling is well-known for its role in regulating cell self-renewal and differentiation. Within the cancer research field, it has been identified that dysregulated Notch signaling is involved directly with various types of cancer. Although Notch signaling is generally considered as oncogenic, it sometimes acts ...

journal_title：Oncology letters

authors： Jia D,Underwood J,Xu Q,Xie Q

更新日期：2019-06-01 00:00:00

abstract：:Virosecurinine, a primary alkaloid from Securinega suffruticosa plant is known as a potent differentiation-inducing agent in acute leukemia cells. The present study aimed to investigate the effects and underlying mechanisms of virosecurinine on human leukemia THP-1 cells in vitro. The effects of virosecurinine on cell...

journal_title：Oncology letters

authors： Zhang G,Gao X,Zeng H,Li Y,Guo X

更新日期：2018-01-01 00:00:00

abstract：:The aim of the present study was to investigate whether oridonin is able to increase the effects of lentinan (LNT) in HepG2 human hepatoblastoma cells by MTT, flow cytometry, reverse transcription-quantitative polymerase chain reaction and western blot analysis. The in vitro results demonstrated that 20 µg/ml of orido...

journal_title：Oncology letters

authors： Sun Z,Han Q,Duan L,Yuan Q,Wang H

更新日期：2018-02-01 00:00:00

abstract：:The purpose of the present study was to evaluate the recent trend of diagnosing appendiceal diseases through the analysis of appendectomy materials, stressing the importance of their pathological examination. A clinicopathological assessment of patients undergoing an appendectomy was conducted, based on the pathologic...

journal_title：Oncology letters

authors： Tajima T,Tajiri T,Mukai M,Sugiyama T,Hasegawa S,Yamamoto S,Sadahiro S,Shimada H,Makuuchi H

更新日期：2018-05-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 base pairs that regulate the expression of genes by targeting messenger RNA with complementarity with the miRNA base sequence. Regulation of gene expression by miRNAs is crucial in cellular development and differentiation, and recent studies suggest a re...

journal_title：Oncology letters

authors： Yanokura M,Banno K,Kobayashi Y,Kisu I,Ueki A,Ono A,Masuda K,Nomura H,Hirasawa A,Susumu N,Aoki D

更新日期：2010-11-01 00:00:00

abstract：:Arteriosclerosis poses a significant risk to human health and involves the thickening and hardening of the walls of arteries. Accumulated evidence demonstrates that aberrant proliferation of vascular smooth muscle cells (VSMCs) accounts for the onset and progression of arteriosclerosis. Suppression of their proliferat...

journal_title：Oncology letters

authors： Han D,Zhang X,Zhang J,Guo X,Zheng Y,Sui S,Zheng J

更新日期：2016-11-01 00:00:00

abstract：:The present study investigated the anticancer functions of ursolic acid (UA) and its novel derivatives, with a nitrogen-containing heterocyclic scaffold and the privileged fragment at the C-28 position on apoptosis induction, cell proliferation and cell cycle in human BC lines. UA was chemically modified in the presen...

journal_title：Oncology letters

authors： Li W,Zhang H,Nie M,Wang W,Liu Z,Chen C,Chen H,Liu R,Baloch Z,Ma K

更新日期：2018-02-01 00:00:00

abstract：:Renal oncocytoma is one of the most unusual benign lesion, which are usually diagnosed postoperatively, since their differentiation from renal cell carcinoma is challenging. The present study reports two cases of renal oncocytoma in a 60-year-old woman and a 46-year-old man. Relevant clinical and pathological data on ...

journal_title：Oncology letters

authors： Wang Y,Hu YU,Zhai X,Wang W,Dong B,Zhou H

更新日期：2016-07-01 00:00:00

abstract：:Downregulation of microRNA-34a (miR-34a) has frequently been observed in esophageal squamous cell carcinoma (ESCC). However, the underlying role and molecular mechanism of miR-34a in ESCC remains largely unknown. In the current study, it was demonstrated that miR-34a was downregulated and forkhead box M1 (FOXM1), a ta...

journal_title：Oncology letters

authors： Zhou H,Yang L,Xu X,Lu M,Guo R,Li D,Huang Q,Liu Y,Deng G,Xu Y

更新日期：2019-01-01 00:00:00

abstract：:Ameloblastoma is the most common and clinically relevant type of odontogenic tumor. Clear cell odontogenic carcinoma is histologically characterized by solid sheets and nests of clear cells, whereas clear cell ameloblastoma (CCAM) is histologically characterized by an ameloblastomatous component intermixed with an ext...

journal_title：Oncology letters

authors： Gamoh S,Wato M,Akiyama H,Tsuji K,Ishikawa H,Naruse K,Yoshida H,Morita S,Tanaka A,Shimizutani K

更新日期：2017-12-01 00:00:00

abstract：:Preoperative radiotherapy improves local disease control and disease-free survival in patients with advanced rectal cancer; however, a reliable predictive biomarker for the effectiveness of irradiation has yet to be elucidated. Phosphorylation of H2A histone family member X (H2AX) to γ-H2AX is induced by DNA double-st...

journal_title：Oncology letters

authors： Kawashima S,Kawaguchi N,Taniguchi K,Tashiro K,Komura K,Tanaka T,Inomata Y,Imai Y,Tanaka R,Yamamoto M,Inoue Y,Lee SW,Kawai M,Tanaka K,Okuda J,Uchiyama K

更新日期：2020-09-01 00:00:00

abstract：:Resistance to apoptosis is an characteristic of cancer cells that serves a critical function in tumor development and represents a target for antitumor therapy. Isoimperatorin (ISOIM), a coumarin compound, exhibits antitumor functions in multiple types of tumor cells. However, its antitumor effects and molecular mecha...

journal_title：Oncology letters

authors： Yang HB,Gao HR,Ren YJ,Fang FX,Tian HT,Gao ZJ,Song W,Huang SM,Zhao AF

更新日期：2018-05-01 00:00:00

abstract：:The long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) has been identified as an oncogene in numerous diseases, and aberrant lncRNA PVT1 expression has been associated with the development of cancer. However, the underlying mechanism by which lncRNA PVT1 affects cell invasion in esophageal cancer...

journal_title：Oncology letters

authors： Zheng X,Hu H,Li S

更新日期：2016-10-01 00:00:00

abstract：:The aim of the present study was to investigate the underlying molecular mechanisms of the potent cell cycle inhibition and apoptotic effect of luteolin on LoVo human colon cancer cells. In the present study, Cell Counting kit-8 assay revealed that luteolin exerted notable cytotoxicity on LoVo cells in a dose- and tim...

journal_title：Oncology letters

authors： Chen Z,Zhang B,Gao F,Shi R

更新日期：2018-02-01 00:00:00

abstract：:The present study was conducted to evaluate the methanolic extract of Piper betle leaves (MPBL) and its organic fractions with regard to antitumor activity against Ehrlich ascites carcinoma (EAC) in Swiss albino mice and to confirm their antioxidant activities. At 24 h post-intraperitoneal inoculation of tumor cells i...

journal_title：Oncology letters

authors： Alam B,Majumder R,Akter S,Lee SH

更新日期：2015-02-01 00:00:00

abstract：:Effect of microRNA-27b (miR-27b) on cisplatin chemotherapy sensitivity of oral squamous cell carcinoma (OSCC) was investigated to provide a reference for clinical prevention of OSCC cell resistance. The clinical tissues of 34 patients with OSCC-resistant cancer and 28 patients with cisplatin-sensitive OSCC in Nanjing ...

journal_title：Oncology letters

authors： Liu B,Cao G,Dong Z,Guo T

更新日期：2019-07-01 00:00:00

abstract：:A standard treatment for patients with early-stage non-small cell lung cancer (NSCLC) who undergo surgery, and subsequently develop local failure or intrathoracic oligo-recurrence, has not yet been established. The present study aimed to assess the feasibility of stereotactic body radiotherapy (SBRT) for this subgroup...

journal_title：Oncology letters

authors： Aoki S,Yamashita H,Takahashi W,Nawa K,Ota T,Imae T,Ozaki S,Nozawa Y,Nakajima J,Sato M,Anraku M,Nitadori J,Karasaki T,Abe O,Nakagawa K

更新日期：2020-04-01 00:00:00

abstract：:The aim of this study was to evaluate the efficacy of multi-detector row helical computed tomography (MDCT) angiography in the detection of feeding arteries prior to multi-arterial infusion for lung cancer. A total of 59 consecutive patients (44 males and 15 females; age range, 27-86 years; median age, 62 years) with ...

journal_title：Oncology letters

authors： Ye XD,Yuan Z,Ye JD,Xiao XS

更新日期：2013-01-01 00:00:00

abstract：:Breast cancer is the most common malignant disease occurring in women. Conservative breast cancer surgery followed by radiation therapy is currently the standard treatment for this type of cancer. The majority of metastases occur within the scar, which initiated a series of studies. As a result, clinical trials aimed ...

journal_title：Oncology letters

authors： Zaleska K,Przybyła A,Kulcenty K,Wichtowski M,Mackiewicz A,Suchorska W,Murawa D

更新日期：2017-10-01 00:00:00

abstract：:A gallbladder neuroendocrine neoplasm (GB-NEN) is a unique heterogeneous neoplasm, originating from neuroendocrine cells and able to secrete peptides as its neurotransmitter. Among all the neuroendocrine tumors (NETs), the GB-NEN prevalence is 0.5%, which accounts for ~2.1% of all gallbladder tumors. The current study...

journal_title：Oncology letters

authors： Niu C,Wang S,Guan Q,Ren X,Ji B,Liu Y

更新日期：2020-05-01 00:00:00

abstract：:The aim of this study was to investigate the correlation between Girdin and PI3K in breast cancer stem cells and the clinical implications of the co-expression of these two proteins in breast cancer patients. CD44+/CD24- tumor cells from the MD-231 cell line were sorted by flow cytometry. The expression status of Gird...

journal_title：Oncology letters

authors： Jin F,Liu C,Guo Y,Chen H,Wu Y

更新日期：2013-05-01 00:00:00

abstract：:Previous studies have revealed the aberrant expression of a number of microRNAs (miRNA/miRs) in the blood circulation of patients with breast cancer (BC). The aim of the present study was to assess the effect of neoadjuvant chemotherapy on the levels of a panel of BC-associated miRNAs, which are at relatively low (let...

journal_title：Oncology letters

authors： Gezer U,Keskin S,Iğci A,Tükenmez M,Tiryakioğlu D,Cetinkaya M,Dişci R,Dalay N,Eralp Y

更新日期：2014-08-01 00:00:00

abstract：:The DNA methyltransferase 3A (DNMT3A) -448A>G polymorphism is a novel functional single nucleotide polymorphism (SNP) that contributes to the genetic susceptibility to gastric cancer. In this study, we aimed to assess the genotype frequencies of DNMT3A -448A>G in colorectal cancer (CRC) patients and healthy control su...

journal_title：Oncology letters

authors： Zhao Z,Li C,Song Y,Wu Q,Qiao F,Fan H

更新日期：2012-02-01 00:00:00

abstract：:The present study aimed to investigate the impact of overexpression of long noncoding RNA PEG10 (lncRNA PEG10) on the proliferation, invasion and metastasis of hypopharyngeal squamous cell carcinoma (HSCC). Quantitative reverse transcription polymerase chain reaction was used to quantify lncRNA PEG10 expression levels...

journal_title：Oncology letters

authors： Zhao M,Sun D,Li X,Xu Y,Zhang H,Qin Y,Xia M

更新日期：2017-09-01 00:00:00

abstract：:Early mitotic inhibitor-1 (Emi1), as a key cell cycle regulatory gene, induces S phase and mitotic entry by controlling anaphase-promoting complex substrates. Emi1 overexpression may be a prognostic factor for patients with invasive breast cancer. However, its expression and clinical significance in esophageal squamou...

journal_title：Oncology letters

authors： Guan C,Zhang J,Zhang J,Shi H,Ni R

更新日期：2016-07-01 00:00:00

abstract：:High mobility group box 1 (HMGB1) functions as a chromatin-associated nuclear protein and an extracellular signaling molecule. The concentration of HMGB1 protein and the expression of HMGB1 mRNA were analyzed by ELISA and polymerase chain reaction (PCR), respectively. The present study reports high plasma HMGB1 levels...

journal_title：Oncology letters

authors： Kimura R,Mori N

更新日期：2014-04-01 00:00:00

abstract：:Plant secondary metabolites including alkaloids, demonstrate a complex diversity in their molecular scaffolds and exhibit tremendous pharmacological potential as anti-cancerous therapeutics. The present study aimed to evaluate the anticancer activity of a natural alkaloid, mecambridine, against human oral squamous cel...

journal_title：Oncology letters

authors： Lin N,Li Z,Wang D,Zheng K,Wu Y,Wang H

更新日期：2018-01-01 00:00:00

abstract：:Radiation enterocolitis is a severe adverse event that occurs after radiotherapy for malignant abdominal tumors. In this study, the therapeutic effects of ETS-GS, a novel vitamin E derivative with antioxidative and anti-inflammatory abilities, were examined in a rat model of radiation enterocolitis. The radiation ente...

journal_title：Oncology letters

authors： Sugita S,Inomata M,Kono Y,Shiroshita H,Etoh T,Shiraishi N,Kitano S

更新日期：2013-11-01 00:00:00

abstract：:The clinicopathological value and exploration of the potential molecular mechanism of microRNA-183-5p (miR-183-5p) have been investigated in various cancers; however, to the best of the author's knowledge, no similar research has been reported for bladder cancer. In the present study, it was revealed that the expressi...

journal_title：Oncology letters

authors： Gao JM,Huang LZ,Huang ZG,He RQ

更新日期：2018-04-01 00:00:00

abstract：:A 39-year-old female presented to The First Affiliated Hospital of Jishou University (Jishou, Hunan) with a fever of unknown origin and progressive abdominal distension. Physical examination revealed generalized lymphadenopathy, multiple non-tender cutaneous nodules, hepatomegaly, splenomegaly and abdominal edema. An ...

journal_title：Oncology letters

authors： Song K,Li M

更新日期：2015-05-01 00:00:00