Abstract:
OBJECTIVES:(1) To compare the prevalence of preclinical atherosclerosis in diabetic vs. non-diabetic rheumatoid arthritis (RA) patients; (2) to determine the influence of classical and RA-related factors on atherosclerosis; (3) to assess the usefulness of combined carotid and femoral ultrasonography in detecting atherosclerosis. METHODS:The study comprised 42 non-diabetic RA patients, 42 diabetic RA patients and 42 controls. Intima media thickness (IMT) was measured in the common carotid and superficial femoral arteries. These vessels were screened for atherosclerotic plaque. RESULTS:Plaque was more prevalent in diabetic RA patients than in non-diabetic RA patients or controls. Carotid IMT and femoral IMT were higher in diabetic RA patients compared to controls. So was femoral IMT in diabetic compared to non-diabetic RA patients. The prevalence of increased IMT and plaque was comparable in carotid ultrasonography and combined carotid and femoral ultrasonography in all groups. CONCLUSIONS:Subclinical atherosclerosis was found to be higher in diabetic RA patients than in non-diabetic RA patients. The combination of carotid and femoral artery ultrasonography did not improve the detection of atherosclerosis in RA.
journal_name
Pak J Med Scijournal_title
Pakistan journal of medical sciencesauthors
Kisiel B,Kruszewski R,Juszkiewicz A,Kłos K,Tłustochowicz M,Tłustochowicz Wdoi
10.12669/pjms.315.7620subject
Has Abstractpub_date
2015-09-01 00:00:00pages
1078-83issue
5eissn
1682-024Xissn
1681-715Xpii
PJMS-31-1078journal_volume
31pub_type
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