Prevalence of Atherosclerosis in diabetic and non-diabetic patients with rheumatoid arthritis.

Abstract:

OBJECTIVES:(1) To compare the prevalence of preclinical atherosclerosis in diabetic vs. non-diabetic rheumatoid arthritis (RA) patients; (2) to determine the influence of classical and RA-related factors on atherosclerosis; (3) to assess the usefulness of combined carotid and femoral ultrasonography in detecting atherosclerosis. METHODS:The study comprised 42 non-diabetic RA patients, 42 diabetic RA patients and 42 controls. Intima media thickness (IMT) was measured in the common carotid and superficial femoral arteries. These vessels were screened for atherosclerotic plaque. RESULTS:Plaque was more prevalent in diabetic RA patients than in non-diabetic RA patients or controls. Carotid IMT and femoral IMT were higher in diabetic RA patients compared to controls. So was femoral IMT in diabetic compared to non-diabetic RA patients. The prevalence of increased IMT and plaque was comparable in carotid ultrasonography and combined carotid and femoral ultrasonography in all groups. CONCLUSIONS:Subclinical atherosclerosis was found to be higher in diabetic RA patients than in non-diabetic RA patients. The combination of carotid and femoral artery ultrasonography did not improve the detection of atherosclerosis in RA.

journal_name

Pak J Med Sci

authors

Kisiel B,Kruszewski R,Juszkiewicz A,Kłos K,Tłustochowicz M,Tłustochowicz W

doi

10.12669/pjms.315.7620

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

1078-83

issue

5

eissn

1682-024X

issn

1681-715X

pii

PJMS-31-1078

journal_volume

31

pub_type

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