Abstract:
BACKGROUND:To clarify the role of physical activity in preventing disability in Japan, we investigated the association between amount of leisure-time physical activity and incidence of disability among the young elderly. METHODS:In the New Integrated Suburban Seniority Investigation (NISSIN) project conducted from 1996 to 2013, we followed 2888 community-dwelling adults aged 64-65 years with no history of cerebrovascular disease for a median follow-up of 11.6 years. Disabilities were defined as follows based on the classifications of the Japanese long-term care insurance system: 1) support or care levels (support levels 1-2 or care levels 1-5); 2) care levels 2-5; 3) support or care levels with dementia; and 4) care levels 2-5 or death. In addition, we also assessed 5) all-cause mortality. RESULTS:After controlling for sociodemographic, lifestyle, and medical factors, male participants reporting an activity level of 18.1 metabolic equivalent (MET)-hours/week (the median among those with activities) or more had 52% less risk of being classified as support or care levels with dementia compared with the no activity group (hazard ratio 0.48; 95% confidence interval, 0.25-0.94). No significant association was found among women between amount of leisure-time physical activity and incidence of disability. CONCLUSION:We identified an inverse dose-response relationship between the amount of leisure-time physical activity and the risk of disability with dementia in men. Therefore, a higher level of physical activity should be recommended to young elderly men to prevent disability with dementia.
journal_name
J Epidemioljournal_title
Journal of epidemiologyauthors
Matsunaga T,Naito M,Wakai K,Ukawa S,Zhao W,Okabayashi S,Ando M,Kawamura T,Tamakoshi Adoi
10.1016/j.je.2016.11.004subject
Has Abstractpub_date
2017-11-01 00:00:00pages
538-545issue
11eissn
0917-5040issn
1349-9092pii
S0917-5040(17)30120-Xjournal_volume
27pub_type
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