Abstract:
:High affinity D-[3H]aspartate uptake and amino acid concentrations were examined in synaptosome-enriched preparations of microdissected rat ventral tegmental area 6-7 days following N-methyl-D-aspartate lesions confined to medial prefrontal cortex. Specific reductions were observed in the high affinity uptake of D-[3H]aspartate (59% of control, P less than 0.005) and concentrations of L-aspartate (79% of control, P less than 0.05) in the ventral tegmental area suggesting the presence of an aspartatergic projection from medial prefrontal cortex to this area.
journal_name
Brain Resjournal_title
Brain researchauthors
Christie MJ,Bridge S,James LB,Beart PMdoi
10.1016/0006-8993(85)90140-4subject
Has Abstractpub_date
1985-04-29 00:00:00pages
169-72issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(85)90140-4journal_volume
333pub_type
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