Moving forward on quality of care: role of decision modeling.

abstract：OBJECTIVES:We sought to assess whether high dose estrogen treatment is associated with enhanced arterial reactivity in genetic males. BACKGROUND:Although estrogens have been shown to enhance arterial reactivity in women, and are thereby thought to confer cardiovascular benefit, the vascular effects of long-term estrog...

journal_title：Journal of the American College of Cardiology

authors： McCrohon JA,Walters WA,Robinson JT,McCredie RJ,Turner L,Adams MR,Handelsman DJ,Celermajer DS

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine the association of SCN5A cardiac sodium (Na(+)) channel mRNA splice variants in white blood cells (WBCs) with risk of arrhythmias in heart failure (HF). BACKGROUND:HF is associated with upregulation of two cardiac SCN5A mRNA splice variants that encode prematurely trun...

journal_title：Journal of the American College of Cardiology

authors： Gao G,Brahmanandam V,Raicu M,Gu L,Zhou L,Kasturirangan S,Shah A,Negi SI,Wood MR,Desai AA,Tatooles A,Schwartz A,Dudley SC Jr

更新日期：2014-06-03 00:00:00

abstract：:In an attempt to determine whether mural thrombus in a dilated left ventricle is associated with specific flow patterns, a study was undertaken to assess qualitatively and quantitatively the flow characteristics by conventional pulsed and two-dimensional Doppler color flow examination. Forty patients with cardiomyopat...

journal_title：Journal of the American College of Cardiology

authors： Maze SS,Kotler MN,Parry WR

更新日期：1989-03-15 00:00:00

abstract：OBJECTIVES:We investigated the role of SH2-domain containing phosphatase-1 (SHP-1) in endothelial reduced nicotinamide adenine dinucleotide (phosphate) (NAD[P]H)-oxidase-dependent oxidant production. BACKGROUND:Superoxide (O2*-) generation by endothelial NAD(P)H-oxidase promotes endothelial dysfunction and atheroscler...

journal_title：Journal of the American College of Cardiology

authors： Krötz F,Engelbrecht B,Buerkle MA,Bassermann F,Bridell H,Gloe T,Duyster J,Pohl U,Sohn HY

更新日期：2005-05-17 00:00:00

abstract：:Tricuspid regurgitation is often not apparent on physical examination and several methods are now available to aid in this difficult assessment. Cardiac catheterization using right ventriculography, previously considered the diagnostic standard, has several limitations. Currently available noninvasive tools such as M-...

journal_title：Journal of the American College of Cardiology

authors： DePace NL,Ross J,Iskandrian AS,Nestico PF,Kotler MN,Mintz GS,Segal BL,Hakki AH,Morganroth J

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to test the feasibility of selective elimination of ventriculoatrial (VA) conduction by limited laser photocoagulation of the atrioventricular (AV) node, and to analyze the histologic substrate of unidirectional retrograde block. BACKGROUND:Atrioventricular node reentry require...

journal_title：Journal of the American College of Cardiology

authors： Littmann L,Svenson RH,Bharati S,Lev M,Chuang CH,Kempler P,Splinter R,Tuntelder JR,Tatsis GP

更新日期：1993-02-01 00:00:00

abstract：:Although the entire coronary tree is exposed to the atherogenic effect of the systemic risk factors, atherosclerotic lesions form at specific arterial regions, where low and oscillatory endothelial shear stress (ESS) occur. Low ESS modulates endothelial gene expression through complex mechanoreception and mechanotrans...

journal_title：Journal of the American College of Cardiology

authors： Chatzizisis YS,Coskun AU,Jonas M,Edelman ER,Feldman CL,Stone PH

更新日期：2007-06-26 00:00:00

abstract：BACKGROUND:It is unclear what level of moderate to vigorous intensity physical activity (MVPA) offsets the health risks of sitting. OBJECTIVES:The purpose of this study was to examine the joint and stratified associations of sitting and MVPA with all-cause and cardiovascular disease (CVD) mortality, and to estimate th...

journal_title：Journal of the American College of Cardiology

authors： Stamatakis E,Gale J,Bauman A,Ekelund U,Hamer M,Ding D

更新日期：2019-04-30 00:00:00

abstract：OBJECTIVES:This study sought to investigate the angiographic or intracoronary Doppler variables of stenosis severity that best correlate with the results of dipyridamole echocardiography. BACKGROUND:Quantitative coronary angiography and intracoronary Doppler flow velocity assessments are the commonly used techniques f...

journal_title：Journal of the American College of Cardiology

authors： Danzi GB,Pirelli S,Mauri L,Testa R,Ciliberto GR,Massa D,Lotto AA,Campolo L,Parodi O

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVES:The purpose of the present study was to systematically evaluate the diagnostic utility of mechanical, pharmacological and orthostatic stimulation of the carotid sinus in a consecutive series of patients with recurrent unexplained syncope. BACKGROUND:Carotid sinus hypersensitivity (CSH) is an infrequently re...

journal_title：Journal of the American College of Cardiology

authors： Morillo CA,Camacho ME,Wood MA,Gilligan DM,Ellenbogen KA

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVES:The aim of this randomized, single-blind, controlled trial was to assess N-acetylcysteine effects on contrast-induced nephropathy and reperfusion injury in ST-segment elevation myocardial infarction patients undergoing primary angioplasty with moderate contrast volumes. BACKGROUND:High-dose N-acetylcysteine...

journal_title：Journal of the American College of Cardiology

authors： Thiele H,Hildebrand L,Schirdewahn C,Eitel I,Adams V,Fuernau G,Erbs S,Linke A,Diederich KW,Nowak M,Desch S,Gutberlet M,Schuler G

更新日期：2010-05-18 00:00:00

abstract：OBJECTIVES:We investigated the effect of adrenergic stimulation on left ventricular relaxation in patients with hypertrophic cardiomyopathy. BACKGROUND:Exercise-induced decreases in acceleration of left ventricular relaxation have been observed in patients with hypertrophic cardiomyopathy. However, data on sequential ...

journal_title：Journal of the American College of Cardiology

authors： Izawa H,Yokota M,Nagata K,Iwase M,Sobue T

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVES:The hypothesis of this study was that evaluation of myocardial flow and metabolism using nitrogen-13 (N-13) ammonia kinetic modeling with dynamic positron emission tomographic (PET) imaging could identify regions of myocardial scar and viable myocardium as defined by fluorine-18 fluorodeoxyglucose (F-18 FDG)...

journal_title：Journal of the American College of Cardiology

authors： Beanlands RS,deKemp R,Scheffel A,Nahmias C,Garnett ES,Coates G,Johansen HL,Fallen E

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVES:We performed Holter monitoring on days 4 and 7 after acute myocardial infarction in 109 patients to assess whether ST segment shift would identify those with more severe coronary artery disease, left ventricular dysfunction and unfavorable prognosis. BACKGROUND:Silent myocardial ischemia is a frequent and p...

journal_title：Journal of the American College of Cardiology

authors： Langer A,Minkowitz J,Dorian P,Casella L,Harris L,Morgan CD,Armstrong PW

更新日期：1992-11-15 00:00:00

abstract：:The impact of right bundle branch block on long-term prognosis after anterior wall myocardial infarction is unclear. In 932 patients with Q wave anterior infarction, the short- and long-term prognostic significance of the presence of right bundle branch block was analyzed. Compared with 754 patients without block, 178...

journal_title：Journal of the American College of Cardiology

authors： Ricou F,Nicod P,Gilpin E,Henning H,Ross J Jr

更新日期：1991-03-15 00:00:00

abstract：BACKGROUND:Cardiac allograft vasculopathy (CAV) remains a leading cause of mortality after heart transplantation (HT). Angiotensin-converting enzyme inhibitors (ACEIs) may retard the development of CAV but have not been well studied after HT. OBJECTIVES:This study tested the safety and efficacy of the ACEI ramipril on...

journal_title：Journal of the American College of Cardiology

authors： Fearon WF,Okada K,Kobashigawa JA,Kobayashi Y,Luikart H,Sana S,Daun T,Chmura SA,Sinha S,Cohen G,Honda Y,Pham M,Lewis DB,Bernstein D,Yeung AC,Valantine HA,Khush K

更新日期：2017-06-13 00:00:00

abstract：OBJECTIVES:To test the hypothesis that the cardiac insulin-like growth factor-1 (IGF-1) system is up-regulated in the failing heart, we measured the pericardial (cardiac) and plasma (circulating) IGF-1 levels in coronary artery disease patients. BACKGROUND:Local IGF-1 systems are regulated differently from the systemi...

journal_title：Journal of the American College of Cardiology

authors： Abe N,Matsunaga T,Kameda K,Tomita H,Fujiwara T,Ishizaka H,Hanada H,Fukui K,Fukuda I,Osanai T,Okumura K

更新日期：2006-10-03 00:00:00

abstract：OBJECTIVES:We sought to assess applicability, clinical correlates, and prognostic value of the transfer function method for measuring baroreflex sensitivity (TF-BRS). BACKGROUND:Abnormalities in autonomic reflexes play an important role in the development and progression of chronic heart failure (CHF). Simple and non-...

journal_title：Journal of the American College of Cardiology

authors： Pinna GD,Maestri R,Capomolla S,Febo O,Robbi E,Cobelli F,La Rovere MT

更新日期：2005-10-04 00:00:00

abstract：:Evaluation for patent ductus arteriosus by both Doppler examination and direct two-dimensional echocardiographic visualization has been reported in infants and children. However, visualization of a patent ductus arteriosus in preterm infants with lung disease has been difficult. Using a recently developed 7.5 MHz mech...

journal_title：Journal of the American College of Cardiology

authors： Vick GW 3rd,Huhta JC,Gutgesell HP

更新日期：1985-04-01 00:00:00

abstract：:Four electrocardiographic scoring systems for the assessment of left ventricular function or presence of myocardial infarction were evaluated in 231 patients with coronary artery disease. Electrocardiographic scores were compared with radionuclide ejection fraction and thallium perfusion studies. The correlation betwe...

journal_title：Journal of the American College of Cardiology

authors： Young SG,Abouantoun S,Savvides M,Madsen EB,Froelicher V

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVES:The aim of our study was to assess the value of transesophageal echocardiography (TEE) in predicting embolic events (EEs) in a large group of patients with definite endocarditis according to the Duke criteria, including silent embolism. BACKGROUND:The value of echocardiography in predicting embolism in pati...

journal_title：Journal of the American College of Cardiology

authors： Di Salvo G,Habib G,Pergola V,Avierinos JF,Philip E,Casalta JP,Vailloud JM,Derumeaux G,Gouvernet J,Ambrosi P,Lambert M,Ferracci A,Raoult D,Luccioni R

更新日期：2001-03-15 00:00:00

abstract：OBJECTIVES:The aim of this research was to assess the efficacy of paclitaxel-eluting stents in chronic total coronary occlusions (CTO). BACKGROUND:Percutaneous coronary interventions for CTOs are characterized by a high target vessel failure rate. METHODS:In 48 consecutive patients, paclitaxel-eluting stents (Taxus, ...

journal_title：Journal of the American College of Cardiology

authors： Werner GS,Krack A,Schwarz G,Prochnau D,Betge S,Figulla HR

更新日期：2004-12-21 00:00:00

abstract：BACKGROUND:Patients with severe aortic stenosis (AS) who were deemed too high risk or inoperable for conventional aortic valve replacement (AVR) in the PARTNER (Placement of Aortic Transcatheter Valves) trial were randomized to transcatheter aortic valve replacement (TAVR) versus AVR (PARTNER-A arm) or standard therapy...

journal_title：Journal of the American College of Cardiology

authors： Svensson LG,Blackstone EH,Rajeswaran J,Brozzi N,Leon MB,Smith CR,Mack M,Miller DC,Moses JW,Tuzcu EM,Webb JG,Kapadia S,Fontana GP,Makkar RR,Brown DL,Block PC,Guyton RA,Thourani VH,Pichard AD,Bavaria JE,Herrmann HC

更新日期：2014-07-15 00:00:00

abstract：:Myocardial ischemia of short duration (15 to 20 min) produces myocardial "stunning" during reperfusion. The vasoregulatory and contractile status of reperfused myocardium during normal and reduced perfusion pressures is of interest in the treatment of patients with unstable angina. In the present study the effects of ...

journal_title：Journal of the American College of Cardiology

authors： Ito BR,Libraty DH,Engler RL

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVES:We sought to investigate the effect of cardiac medication on long-term mortality in patients with peripheral arterial disease (PAD). BACKGROUND:Peripheral arterial disease is associated with increased cardiovascular morbidity and mortality. Treatment guidelines recommend aggressive management of risk factor...

journal_title：Journal of the American College of Cardiology

authors： Feringa HH,van Waning VH,Bax JJ,Elhendy A,Boersma E,Schouten O,Galal W,Vidakovic RV,Tangelder MJ,Poldermans D

更新日期：2006-03-21 00:00:00

abstract：BACKGROUND:The underlying etiology of ischemic stroke remains unknown in up to 30% of patients. OBJECTIVES:This study explored the causal role of complicated (American Heart Association-lesion type VI) nonstenosing carotid artery plaques (CAPs) in cryptogenic stroke (CS). METHODS:CAPIAS (Carotid Plaque Imaging in Acu...

journal_title：Journal of the American College of Cardiology

authors： Kopczak A,Schindler A,Bayer-Karpinska A,Koch ML,Sepp D,Zeller J,Strecker C,Hempel JM,Yuan C,Malik R,Wollenweber FA,Boeckh-Behrens T,Cyran CC,Helck A,Harloff A,Ziemann U,Poli S,Poppert H,Dichgans M,Saam T

更新日期：2020-11-10 00:00:00

abstract：OBJECTIVES:The Air Primary Angioplasty in Myocardial Infarction (PAMI) study was designed to determine the best reperfusion strategy for patients with high-risk acute myocardial infarction (AMI) at hospitals without percutaneous transluminal coronary angioplasty (PTCA) capability. BACKGROUND:Previous studies have sugg...

journal_title：Journal of the American College of Cardiology

authors： Grines CL,Westerhausen DR Jr,Grines LL,Hanlon JT,Logemann TL,Niemela M,Weaver WD,Graham M,Boura J,O'Neill WW,Balestrini C,Air PAMI Study Group.

更新日期：2002-06-05 00:00:00

abstract：OBJECTIVES:In a computed tomographic (CT) angiography study, we identified the characteristics of atherosclerotic lesions that were associated with subsequent development of acute coronary syndrome (ACS). BACKGROUND:The CT characteristics of culprit lesions in ACS include positive vessel remodeling (PR) and low-attenu...

journal_title：Journal of the American College of Cardiology

authors： Motoyama S,Sarai M,Harigaya H,Anno H,Inoue K,Hara T,Naruse H,Ishii J,Hishida H,Wong ND,Virmani R,Kondo T,Ozaki Y,Narula J

更新日期：2009-06-30 00:00:00

abstract：:This is a review of the important randomized trials of intracoronary and intravenous streptokinase therapy for treatment of acute myocardial infarction. Trials carried out before 1980 failed to recognize the relations between early coronary reperfusion and myocardial salvage and therefore have not been included in thi...

journal_title：Journal of the American College of Cardiology

authors： Kennedy JW

更新日期：1987-11-01 00:00:00

abstract：:Acute and chronic hemodynamic and clinical responses to milrinone, a new oral inotrope-vasodilator agent, were evaluated prospectively in 37 patients with severe congestive heart failure. The majority of patients (n = 31) had not responded to prior vasodilator therapy, with a substantial number (n = 8) requiring intra...

journal_title：Journal of the American College of Cardiology

authors： Simonton CA,Chatterjee K,Cody RJ,Kubo SH,Leonard D,Daly P,Rutman H

更新日期：1985-08-01 00:00:00