Genetic and Environmental Influences on Longitudinal Trajectories of Functional Biological Age: Comparisons Across Gender.

Abstract:

:We used an alternate age variable, functional biological age (fBioAge), which was based on performance on functional body measures. The aim was to examine development of fBioAge across the adult life span, and to also examine potential gender differences and genetic and environmental influences on change with age. We used longitudinal data (n = 740; chronological age (ChronAge) range 45-85 at baseline) from the Swedish Adoption/Twin Study of Aging. The rate of increase in fBioAge was twice as fast after ChronAge 75 than before. fBioAge was higher in women than in men. fBioAge was fairly equally influenced by genetic and environmental factors. Whereas the rate of ChronAge cannot vary across time, gender, or individual, our analyses demonstrate that fBioAge does capture these within and between individual differences in aging, providing advantages for fBioAge in the study of aging effects.

journal_name

Behav Genet

journal_title

Behavior genetics

authors

Finkel D,Sternäng O,Wahlin Å

doi

10.1007/s10519-017-9851-5

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

375-382

issue

4

eissn

0001-8244

issn

1573-3297

pii

10.1007/s10519-017-9851-5

journal_volume

47

pub_type

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