Helicobacter pylori infection in dyspeptic patients in an industrial belt of India.

Abstract:

:The present study is done to study different aspects of Helicobacter pylori (H. pylori) such as its prevalence, association with upper gastrointestinal pathology, diagnosis and treatment outcome. Gastric antral biopsy and serology for H. pylori was done for all dyspeptic patients. Histopathology, gram stain and biopsy urease test was done from the gastric biopsy specimen. The prevalence of H. pylori infection was 58.8%. The sensitivity, specificity, positive and negative predictive value for histopathology was 96.9%, 100%, 100% and 95.8%, respectively; for biopsy urease test 80.4%, 100%, 100% and 78.2%, respectively; for gram stain 85.6%, 97.1%, 97.6% and 82.5%, respectively, and for serology 94.8%, 77.9%, 86% and 91.4%, respectively. Mostly peptic ulcer and duodenitis cases followed by chronic active gastritis were associated with H. pylori infection. Repeat biopsy revealed eradication of H. pylori in 90.7% cases. In dyspeptic patients, endoscopic biopsy not only detects H. pylori infection, but also reveals different gastric pathologies.

journal_name

Trop Doct

journal_title

Tropical doctor

authors

Satpathi P,Satpathi S,Mohanty S,Mishra SK,Behera PK,Maity AB

doi

10.1177/0049475515626033

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

2-6

issue

1

eissn

0049-4755

issn

1758-1133

pii

0049475515626033

journal_volume

47

pub_type

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