Abstract:
:Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by pathophysiological factors including airflow limitation, hyperinflation and reduced gas exchange. Treatment consists of lifestyle changes, lung rehabilitation and pharmacological therapies such as long acting beta-2-agonists (LABA) and long acting muscarinic antagonists (LAMA). More recently bronchoscopic treatments are emerging for COPD. Among them endobronchial valves (EBV) and endobronchial coils (EBC), next to endobronchial stents, sclerosing agents, targeted lung denervation and liquid nitrogen metered cryospray. In this review we aim to summarize the new emerging bronchoscopic treatments and their effect sizes compared with lung rehabilitation and pharmacological therapies.
journal_name
Pharmacol Therjournal_title
Pharmacology & therapeuticsauthors
van Geffen WH,Kerstjens HAM,Slebos DJdoi
10.1016/j.pharmthera.2017.05.007subject
Has Abstractpub_date
2017-11-01 00:00:00pages
96-101eissn
0163-7258issn
1879-016Xpii
S0163-7258(17)30126-2journal_volume
179pub_type
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