Efficacy of the Bunium persicum (Boiss) Essential Oil against Acute Toxoplasmosis in Mice Model.

Abstract:

BACKGROUND:We evaluated the in vivo activity of Bunium persicum (Boiss) essential oil on infected mice with acute toxoplasmosis. METHODS:To evaluate prophylactic effects, male NMRI mice received B. persicum essential oil at the concentrations of 0.05 and 0.1 mL/kg for 14 days. After 24 h mice were infected intraperitonealy with 1×10(4) tachyzoites of T. gondii, RH strain. In order to investigate therapeutic effects, mice were infected and then received B. persicum oil at the concentrations of 0.05 and 0.1 ml/kg two times a day for 5 days. The time/mean time of death in all infected mice and the number of tachyzoites from infected mice were recorded. RESULTS:The time/mean time of death of infected mice was 8 and 9 days after oral administration of B. persicum oil at the concentration of 0.05 and 0.1 mL/kg, respectively (P<0.05). In contrast, the time/mean time of death control group was 5 days. In addition, B. persicum significantly reduced the mean number of tachyzoites compared with control group. The time/mean time of death of infected mice was 6 and 7 days after oral administration of B. persicum essential oil at the concentration of 0.05 and 0.1 mL/kg, respectively. In contrast, the time/mean time of death control group was 5 days. B. persicum especially at the concentration of 0.1 ml/kg significantly reduced the mean number of tachyzoites compared with control group. CONCLUSION:The results showed the potential of B. persicum essential oil as a natural source for the production of new prophylactic agent for use in toxoplasmosis.

journal_name

Iran J Parasitol

authors

Tavakoli Kareshk A,Keyhani A,Mahmoudvand H,Tavakoli Oliaei R,Asadi A,Andishmand M,Azzizian H,Babaei Z,Zia-Ali N

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

625-31

issue

4

eissn

1735-7020

issn

2008-238X

journal_volume

10

pub_type

杂志文章
  • Evaluation of Immune Response against Leishmaniasis in BALB/c Mice Immunized with Cationic DOTAP/DOPE/CHOL Liposomes Containing Soluble Leishmania major Antigens.

    abstract:Background:Whole killed Leishmania vaccine reached phase III clinical trials but failed to display significant efficacy in human mainly due to limited Th1 inducer adjuvant. Liposomes consisting of 1, 2-dioleoyl-3trimethylammonium-propane (DOTAP) bearing an inherent adjuvanticity and 1, 2-dioleoyl-L-α-glycero-3-phosphat...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Hojatizade M,Badiee A,Khamesipour A,Jaafari MR

    更新日期:2019-01-01 00:00:00

  • Gluteal Hydatid Cyst: A Case Report.

    abstract::Hydatid cyst caused by Echinococcus granulosus usually involves lung and liver but can appear in other organs. We report a 29-yr-old woman presented to Fatemi Hospital, Ardabil, Iran in 2017 with progressive painful swelling of the left gluteus which in imaging showed hydatid cyst. The cyst was successfully en blocked...

    journal_title:Iranian journal of parasitology

    pub_type:

    doi:

    authors: Seyedsadeghi M,Ghobadi J,Haghshenas N,Habibzadeh A

    更新日期:2019-07-01 00:00:00

  • Enterobius vermicularis in the Endometrium of the Uterus: A Case Report.

    abstract::Enterobius vermicularis is an intestinal nematode of humans and the most common helminth infection. Main transmission path is direct contact between infected and uninfected person meaning ingestion of the eggs. Human infections are usually asymptomatic or manifest as perianal itching. Although ectopic locations are un...

    journal_title:Iranian journal of parasitology

    pub_type:

    doi:

    authors: Pigac B,Mašić S,Mašić V

    更新日期:2017-10-01 00:00:00

  • Study on ITS1 Gene of Iranian Trichomonas vaginalis by Molecular Methods.

    abstract:BACKGROUND:Trichomoniasis is a worldwide protozoan parasitic disease and metronidazole is a choice drug for its treatment. Because of disease importance in public health and its controversial ideas about the prevalence of drug resistance, this study was carried out. METHODS:Fifty-two suspected vaginal samples were col...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Kazemi F,Hooshyar H,Zareikar B,Bandehpour M,Arbabi M,Talari S,Alizadeh R,Kazemi B

    更新日期:2010-12-01 00:00:00

  • An incidental diagnosis of neurocysticercosis in a dental patient.

    abstract::Tenia solium, a parasite causes cysticercous cellulose when affecting the central nervous system, the manifestation is called neurocysticercosis. The most common symptom in neurocysticercosis is seizure. Generally, oral diagnosticians come across cases of oral cysticercosis and it is rare to find a case of neurocystic...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Puttaraju MK,Hanasoge Srivathsa S

    更新日期:2013-10-01 00:00:00

  • Double-Blind Randomized Efficacy Field Trial of Alum Precipitated Autoclaved Leishmania major (Alum-ALM) Vaccine Mixed With BCG Plus Imiquimod Vs. Placebo Control Group.

    abstract:BACKGROUND:Canine visceral leishmaniasis (CVL) is not only an emerging veterinary concern but also a public health threat in endemic areas. The aim of this study was to assess the efficacy, immunogenicity and safety of two doses of aluminum hydroxide (alum) precipitated Leishmania major (Alum-ALM) mixed with BCG plus i...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Barati M,Mohebali M,Alimohammadian MH,Khmesipour A,Keshavarz H,Akhoundi B,Zarei Z

    更新日期:2015-07-01 00:00:00

  • Hydatid Cyst Surgeries in Patients Referred to Hospitals in East Azerbaijan Province during 2009-2011.

    abstract:BACKGROUND:Hydatidosis, as the most important zoonotic parasitic disease in Iran, has posed many health and economic losses. This study was conducted to investigate the demographic characteristics of hydatid cyst surgeries in hospitals of East Azerbaijan Province, Northwest of Iran. METHODS:Demographic characteristics...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Ghabouli Mehrabani N,Kousha A,Khalili M,Mahami Oskouei M,Mohammadzadeh M,Alizadeh S,Maleksabet A,Hamidi F

    更新日期:2014-04-01 00:00:00

  • Protection Efficacy of Multivalent Egg Yolk Immunoglobulin against Eimeria tenella Infection in Chickens.

    abstract:BACKGROUND:To control avian coccidiosis with drug-independent strategy effectively and safely, multivalent hyperimmune egg yolk immunoglobulin (IgY) was prepared and its ability to protect against Eimeria tenella infection was evaluated. METHODS:Hens were orally immunized with live oocysts of 5 species of Eimeria for ...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Xu J,Ren C,Wang S,Liu D,Cao L,Tao J

    更新日期:2013-07-01 00:00:00

  • Epidemiology of Urinary Schistosomiasis among School Children in the Alsaial Alsagair Village, River Nile State, Sudan.

    abstract:BACKGROUND:Schistosomiasis is a debilitating disease, infects millions of people in tropical and subtropical regions. This study assessed the situation of the urinary schistosomiasis among schoolchildren of the Alsaial Alsagair village, Sudan. METHODS:A cross-sectional survey was carried out in 2016, in the Alsaial Al...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Sulieman Y,Eltayeb RE,Pengsakul T,Afifi A,Zakaria MA

    更新日期:2017-04-01 00:00:00

  • Evaluation of the leishmanicidal and cytotoxic potential of essential oils derived from ten colombian plants.

    abstract:BACKGROUND:The leishmanicidal and cytotoxic activity of ten essential oils obtained from ten plant specimens were evaluated. METHODS:Essential oils were obtained by the steam distillation of plant leaves without any prior processing. Cytotoxicity was tested on J774 macrophages and leishmanicidal activity was assessed ...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Sanchez-Suarez J,Riveros I,Delgado G

    更新日期:2013-01-01 00:00:00

  • Expression Analysis of Multiple Genes May Involve in Antimony Resistance among Leishmania major Clinical Isolates from Fars Province, Central Iran.

    abstract:BACKGROUND:Treatment of Cutaneous Leishmaniasis (CL) is being faced with serious difficulties in Fars Province, due to emerging of resistance against meglumine antimonite (Glucantime®). In this context, determining some biomarkers for drug sensitivity monitoring seems to be highly essential. Different studies have been...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Ghobakhloo N,Motazedian MH,Fardaei M

    更新日期:2016-04-01 00:00:00

  • Trypanocidal Effects of Cisplatin alone and in Combination with Nigella sativa Oil on Experimentally Infected Mice with Trypanosoma evansi.

    abstract:Background:Due to the limited number of the available drugs for the treatment of trypanosomiasis, this study was designed to evaluate the trypanocidal effects of cisplatin or/and Nigella sativa oil (NSO) in experimentally infected mice with T. evansi. Methods:During 2015 at the Parasitology Department, Menoufia Univer...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Nassef NAE,El-Melegy MA,Beshay EV,Al-Sharaky DR,Al-Attar TM

    更新日期:2018-01-01 00:00:00

  • In Vitro Assessment of Balanites aegyptiaca Fruit Methanolic Extract on the Adult Toxocara canis.

    abstract:Background:The effectiveness of anthelmintics may diminish within approximately 10 yr of use relying on several factors such as anthelmintic resistance. This study aimed to assess in vitro effect of Balanites aegyptiaca fruits extract on the cuticle of adult worm of Toxocara canis as naturally alternative therapy. Met...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Shalaby H,El Namaky A,Kandil O,Hassan N

    更新日期:2018-10-01 00:00:00

  • Comparison between Combination Therapy of Oral Terbinafine and Cryotherapy versus Systemic Meglumine Antimoniate and Cryotherapy in Cutaneous Leishmaniasis: A Randomized Clinical Trial.

    abstract:BACKGROUND:Leishmaniasis is a parasitic infection that may lead to a variety of manifestations. In Iran, cutaneous leishmaniasis (CL) has a high prevalence. There are many treatment modalities for CL. The use of oral terbinafine in the treatment of CL has recently been considered. The aim of this study was to compare c...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Farajzadeh S,Esfandiarpour I,Haghdoost AA,Mohammadi S,Mohebbi A,Mohebbi E,Mostafavi M

    更新日期:2015-01-01 00:00:00

  • Diagnosing Malaria Cases Referred to the Malaria Reference Laboratory in Tehran University of Medical Science, Iran.

    abstract:BACKGROUND:The number of malaria cases is declining worldwide; however, it remains as a serious health problem. Diagnosing unusual cases is the most important issue to manage the problem. This study designed to describe the number of falciparum and vivax malaria infected patients referred to Malaria Reference Laborator...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Nateghpour M,Edrissian G,Motevalli Haghi A,Farivar L,Kazemi-Rad E

    更新日期:2015-10-01 00:00:00

  • Identification of leishmania species using PCR assay on giemsa-stained slides prepared from cutaneous leishmaniasis patients.

    abstract:BACKGROUND:Leishmaniasis is a group of diseases that are created by intracellular parasites of Leishmania. Cutaneous leishmaniasis is considered as one of the health problems in some provinces of Iran. METHODS:In this study, a total of 178 Giemsa-stained slides from confirmed cases of cutaneous leishmaniasis were exam...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Kheirandish F,Chegeni Sharafi A,Kazemi B,Mohebali M,Sarlak A,Tarahi MJ,Holakouee K,Hajaran H

    更新日期:2013-07-01 00:00:00

  • Surgical Management of Liver Hydatid Cyst Related Non-traumatic Emergencies: Single Center Experience.

    abstract:BACKGROUND:Vast majority of complaints and physical examination findings of hydatid disease are common in emergency room patients. Different emergency presentations of hydatid cyst disease and their treatment are evaluated. We studied preoperative laboratory findings of these patients to identify any parameters to pred...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Dinc T,Kayilioglu SI,Akturk OM,Coskun F

    更新日期:2016-10-01 00:00:00

  • Prevalence of Intestinal Parasites among Rural Inhabitants of Fouman, Guilan Province, Northern Iran with Emphasis on Strongyloides stercoralis.

    abstract:Background:Intestinal parasitic infections (IPIs) are among the most important etiologies of gastrointestinal disorders in developing countries. The present study was performed to determine the prevalence of IPIs in rural inhabitants of Fouman, northern Iran. Methods:Overall, 31 villages were randomly selected during ...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Sharifdini M,Ghanbarzadeh L,Barikani A,Saraei M

    更新日期:2020-01-01 00:00:00

  • Molecular characterization of eimeria species naturally infecting egyptian baldi chickens.

    abstract:BACKGROUND:Coccidiosis is a serious protozoal disease of poultry. The identification of Eimeria species has important implications for diagnosis and control as well as for epidemiology. The molecular characterization of Eimeria species infecting Egyptian baladi chickens was investigated. METHODS:Eimeria species oocyst...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Gadelhaq SM,Arafa WM,Aboelhadid SM

    更新日期:2015-01-01 00:00:00

  • Determination of the Infectivity of Cryopreserved Theileria annulata Sporozoites in Tick Derived Stabilates Iran Ak-93 Strain, by In Vivo and In Vitro Methods.

    abstract:Background:The protozoan parasite Theileria annulata is the causative agent of tropical theileriosis in cattle. Vaccination is recommended by administration of attenuated schizont-infected cell lines. The expected protective immunity post-vaccination can be demonstrated by challenge test through inoculation of highly v...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Modirrousta H,Habibi G,Shayan P,Afshari A,Mirjalili A,Abdigoudarzi M

    更新日期:2019-10-01 00:00:00

  • Absence of asymptomatic malaria infection in endemic area of bashagard district, hormozgan province, iran.

    abstract:BACKGROUND:A successful malaria elimination program calls for enough attention to parasite carriers, especially asymptomatic malaria, as well as the diagnosis and treatment of clinical cases. Asymptomatic malaria is an infection that patients do not show any symptom; thus, these patients play critical role in the conce...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Turki H,Zoghi S,Mehrizi AA,Zakeri S,Raeisi A,Khazan H,Haghdoost A

    更新日期:2012-01-01 00:00:00

  • Development and Assessment of Loop-Mediated Isothermal Amplification (LAMP) Assay for the Diagnosis of Human Visceral Leishmaniasis in Iran.

    abstract:BACKGROUND:Parasitological methods for the diagnosis of Visceral leishmaniasis (VL) require invasive procedures, so serological and molecular approaches have been developed but are not generally applicable in the field. We evaluated a loop mediated isothermal amplification (LAMP) assay using blood from VL patients and ...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Ghasemian M,Gharavi MJ,Akhlaghi L,Mohebali M,Meamar AR,Aryan E,Oormazdi H

    更新日期:2014-03-01 00:00:00

  • Disseminated Leishmaniasis Due to Using Immunosuppression Drugs: A Case Report.

    abstract::Visceral leishmaniasis is a common parasitic disease between humans and animals, transmitted by sandflies (Phlebotomus) in the Mediterranean countries, including Iran. The statistics have been reported less than real due to errors in the diagnosis and reporting of affected cases. In this report, we will present the sy...

    journal_title:Iranian journal of parasitology

    pub_type:

    doi:

    authors: Afshoon M,Abdolsalehi M,Alinia G,Borhani K,Yaghmaie B,Khodabandeh M

    更新日期:2020-04-01 00:00:00

  • Evaluation of Immunogenicity of Novel Isoform of EG95 (EG95-5G1) From Echinococcus granulosus in BALB/C Mice.

    abstract:BACKGROUND:Echinococcosis is a zoonotic parasitic disease of humans and various herbivorous domestic animals transmitted by the contact with domestic and wild carnivores, mainly dogs and foxes. The aim of this study is the production, purification and evaluation immunogenicity of new construction of EG95 protein. METH...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Pirestani M,Dalimi A,Sarvi S,Khoramabadi N

    更新日期:2014-10-01 00:00:00

  • Gene regulation of pteridine reductase 1 in leishmania promastigotes and amastigotes using a full-length antisense construct.

    abstract:BACKGROUND:Pteridine metabolic pathway is unusual features of Leishmania, which is necessary for the growth of parasite. Leishmania has evolved a complex and versatile pteridine salvage network which has the ability of scavenging a wide area of the conjugated and unconjugated pteridines especially folate and biopterin....

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Kheirandish F,Bandehpour M,Davoudi N,Mosaffa N,Dawood S,Kazemi B,Haghighi A,Khamesipour A,Masjedi H,Mohebali M,Mahboudi F

    更新日期:2013-04-01 00:00:00

  • Iranian Native Plants on Treatment of Cutaneous Leishmaniosis: A Narrative Review.

    abstract:BACKGROUND:Chemotherapy still relies on the use of pentavalent antimonials, amphotericin B, paromomycin, miltefosin, and allopurinol. In this study, we explained about the native plant that grows in different regions of Iran and used as anti-leishmanial in Iran and even many other countries. METHODS:This narrative rev...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章,评审

    doi:

    authors: Moghaddas E,Khamesipour A,Mohebali M,Fata A

    更新日期:2017-07-01 00:00:00

  • Prevalence of Toxocara Spp. eggs in Public Parks in Tehran City, Iran.

    abstract:BACKGROUND:The objective of the present research was to determine the frequency of Toxocara spp. eggs in soil samples of public parks, in the city of Tehran, Iran. METHODS:A total of 600 soil samples were taken from 120 parks between Aprils to November, 2008. Soil samples were collected from 5 distinct sites in the pa...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Khazan H,Khazaei M,Tabaee SS,Mehrabi A

    更新日期:2012-01-01 00:00:00

  • Presence of visceral larva migrans in the urinary bladder of a woman in khorramabad, iran.

    abstract::The presence of Visceral Larva Migrans (VLM) in a patient is reported. A 57-year- old woman suffering from right upper abdominal and suprapubic pain referred into a clinic in Khorramabad, Lorestan Province, Iran. A cystoscopy was performed and biopsy was taken. The light microscopic study showed a couple of larvae as ...

    journal_title:Iranian journal of parasitology

    pub_type:

    doi:

    authors: Rafiee Alavi S,Nayebzadeh H

    更新日期:2011-03-01 00:00:00

  • The First Detection of Co-Infection of Double-Stranded RNA Virus 1, 2 and 3 in Iranian Isolates of Trichomonas vaginalis.

    abstract:Background:The Totiviridae family includes a number of double-stranded RNA viruses that can infect Trichomonas vaginalis. Some T. vaginalis isolates are infected with one or more double-stranded RNA (dsRNA) viruses. In this study, different strains of double-stranded RNA virus in Iranian isolates of T. vaginalis were e...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:10.18502/ijpa.v15i3.4200

    authors: Bokharaei-Salim F,Esteghamati A,Khanaliha K,Esghaei M,Donyavi T,Salemi B

    更新日期:2020-07-01 00:00:00

  • Allelic Variations of Plasmodium vivax Apical Membrane Antigen-1 (Pv AMA-1) in Malarious Areas of Southeastern Iran Using PCR-RFLP Technique.

    abstract:Background:Although Plasmodium vivax is usually known as benign malaria, some variations of the parasite can result in acute and sever infection. In this study we tried to determine some genetic variations in PvAMA-1 antigen among the samples were collected form southeastern Iran. Methods:About two ml blood samples we...

    journal_title:Iranian journal of parasitology

    pub_type: 杂志文章

    doi:

    authors: Motevalli Haghi A,Moradi S,Nateghpour M,Edrissian G

    更新日期:2018-07-01 00:00:00