Abstract:
OBJECTIVES:The impact of ethnicity and the socioeconomic status (SES) among Caucasians is not well studied. Here, we examine the impact of income on melanoma presentation and prognosis within a Caucasian cohort, accounting for ethnicity, as some reports suggest increased melanoma incidence in Ashkenazi Jewish (AJ) BRCA mutation carriers. METHODS:We studied prospectively enrolled primary melanoma patients at New York University. SES data were estimated using United States' Census Bureau data and patient zip codes. We evaluated associations between ethnicity, SES, and baseline characteristics using the χ² test and multivariate logistic regression. We compared survival distributions using Kaplan-Meier curves, log-rank tests, and Cox proportional hazard ratios. RESULTS:Of the 1,339 enrolled patients, AJ represented 32% (n = 423). Apart from AJ being older at presentation (p < 0.001), no significant differences were observed in baseline characteristics between ethnic groups. Patients with a median household income (MHI) lower than the median of the cohort were significantly more likely to present with advanced stages (p < 0.001) compared to patients with a higher MHI. Shorter overall (p = 0.016) and post-recurrence survival (p = 0.042) was also observed in patients from lower-income households. CONCLUSION:Data suggest that disparities in melanoma presentation in Caucasians stratify according to income independent of ethnic background.
journal_name
Oncologyjournal_title
Oncologyauthors
Salvaggio C,Han SW,Martires K,Robinson E,Madankumar R,Gumaste P,Polsky D,Stein J,Berman R,Shapiro R,Zhong J,Osman Idoi
10.1159/000441524subject
Has Abstractpub_date
2016-01-01 00:00:00pages
79-87issue
2eissn
0030-2414issn
1423-0232pii
000441524journal_volume
90pub_type
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