Abstract:
:In summary, the in utero diagnosis of nonimmune hydrops is associated with a grave prognosis. Antenatal evaluation will determine the cause in many cases, allowing appropriate decisions to be made regarding the management of the pregnancy. To date, no specific in utero therapy exists for most causes of nonimmune hydrops fetalis. At the time of delivery, a resuscitation team will be needed for the infant because extensive resuscitation is likely to be necessary. Many infants will die in the first day of life but some will survive; the survivors will probably require intensive newborn care, including mechanical ventilation. A major cause of mortality in babies with nonimmune hydrops is respiratory insufficiency. If pulmonary hypoplasia is present and severe, survival may not be possible despite intensive care. Review of our data suggests that the diagnosis of idiopathic nonimmune hydrops carries the same grave prognosis as other forms. Currently, only babies with nonimmune hydrops secondary to supraventricular tachycardia have a high probability of survival. Parents of hydropic infants should be counseled concerning the probable outcome and the risk of recurrence. A genetic consultant can help in this regard. Infants who die should have a complete postmortem examination, and placental pathology should be performed in all cases.
journal_name
Clin Perinatoljournal_title
Clinics in perinatologyauthors
Carlton DP,McGillivray BC,Schreiber MDsubject
Has Abstractpub_date
1989-12-01 00:00:00pages
839-51issue
4eissn
0095-5108issn
1557-9840journal_volume
16pub_type
杂志文章,评审abstract::There were approximately 2 million deaths worldwide from tuberculosis in 1997, 98% of them in developing countries. Factors implicated in the resurgence of tuberculosis in the United States in the late 80s and early 90s included increased immigration from countries with high prevalence, HIV infection, emergence of res...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2005.04.010
更新日期:2005-09-01 00:00:00
abstract::Most allegations in obstetric lawsuits against obstetrician-gynecologists relate in some manner to the management of labor and delivery; few solely involve perceived flaws in prenatal or postpartum care. Although many of these cases accuse the defendant of not having properly monitored the fetus during labor for signs...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2007.03.011
更新日期:2007-06-01 00:00:00
abstract::Preterm birth remains a significant health concern. Maternal reproductive infections such as bacterial vaginosis pose increased risk for preterm birth, although treatment of bacterial vaginosis has not proven to be universally effective in preterm birth prevention. Maternal oral infection such as clinical periodontal ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2005.05.002
更新日期:2005-09-01 00:00:00
abstract::The extensive data from animal models of BPD and specific aspects of lung injury have helped to expand and refine the concept of pathogenesis introduced by Northway et al. Given the complexity and heterogeneity of the human illness, it is unreasonable to presume that any single model or research group could elucidate ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract::Inherited organic acidemias are a group of metabolic disorders currently being described and investigated as gas-liquid chromatography is applied to unexplained diseases of infancy and childhood. Common clinical presentations include attacks of ketoacidosis, unexplained metabolic acidosis, failure of normal developmen...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1976-03-01 00:00:00
abstract::Administrative data research on maternal racial disparities supports 2 broad clinical inferences. First, failure to rescue in terms of both death and severe maternal morbidity likely accounts for a significant proportion of maternal disparities. Second, risk for adverse outcomes by race is generally differential with ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2020.08.008
更新日期:2020-12-01 00:00:00
abstract::Ischemic perinatal stroke (IPS) occurs in 1 of 2300 to 5000 live births. It is an under-recognized cause of significant long-term disabilities, including hemiplegic cerebral palsy, epilepsy, cognitive delays, and behavioral impairments. The pathophysiology is complex and multifactorial, involving maternal, fetal, plac...
journal_title:Clinics in perinatology
pub_type: 杂志文章
doi:10.1016/j.clp.2008.09.008
更新日期:2009-03-01 00:00:00
abstract::It is clear that prostaglandins and related compounds are important in the physiology and pathophysiology of the perinatal pulmonary circulation. This article focuses on what is known about prostaglandin-related compounds (PRC) in the pulmonary circulation of the developing and newly born mammal. Also included is a di...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1984-10-01 00:00:00
abstract::Neurologically impaired infants have immature, damaged, or abnormally developed nervous systems that may cause abnormalities of sucking and swallowing, among other problems. Sucking abnormalities usually present as absence of the sucking response, weakness or incoordination of sucking and swallowing, or some combinati...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1987-03-01 00:00:00
abstract::Several limitations and controversies surround the definition of hypotension; however, it remains one of the most common problems faced by neonates. Approximately 15% to 30% of neonates with hypotension fail to respond to volume and/or vasopressor or inotropes. They are considered to have refractory hypotension. Altho...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2020.05.015
更新日期:2020-09-01 00:00:00
abstract::Staphylococci are common pathogens in the neonatal period. Increased survival of premature infants leads to prolonged hospital stay with associated risk factors for developing invasive staphylococcal disease. Challenges of diagnosing coagulase-negative staphylococcal infections result in conflicting definitions and in...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2014.10.013
更新日期:2015-03-01 00:00:00
abstract::The fetal environment is thus well suited for normal growth and development with oxygen availability exceeding oxidative needs. With impairments in blood gas exchange this excess oxygen acts as a "margin of safety," providing for the maintenance of oxidative metabolism through increases in fractional O2 extraction, al...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1989-09-01 00:00:00
abstract::Neutropenia, a below normal concentration of neutrophils in the circulating blood, can be the kinetic result of diminished neutrophil production, excessive neutrophil margination, or accelerated neutrophil utilization and destruction. The significance of neutropenia to the well-being of the subject is dependent, in pa...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1995-09-01 00:00:00
abstract::Decision-making for extremely immature preterm infants at the margins of viability is ethically, professionally, and emotionally complicated. A standard for prenatal consultation should be developed incorporating assessment of parental decision-making preferences and styles, a communication process involving a recipro...
journal_title:Clinics in perinatology
pub_type: 杂志文章
doi:10.1016/j.clp.2011.06.004
更新日期:2011-09-01 00:00:00
abstract::Ultrasonography has increasingly become essential in the practice of obstetrics and gynecology. Its antenatal use is well described in the literature and is a continuing subject of study. However, the use of ultrasonography in the labor and delivery suite has not been the subject of many articles. The purpose of this ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1996-03-01 00:00:00
abstract::Numerous articles have chronicled the problems that stem from patients' lack of compliance with health care recommendations, yet there has not been a systematic approach to the development of a strategy for increasing the effectiveness of health education programs. In this article, making use of anticipatory guidance,...
journal_title:Clinics in perinatology
pub_type: 杂志文章
doi:
更新日期:1985-06-01 00:00:00
abstract::The treatment of cocaine abuse among pregnant women involves attention not only to the cocaine use, but also to the pregnancy and constellation of medical and social problems substance-abusing women experience. Writing about the needs of women who enter treatment for drug-dependence treatment, Reed has offered suggest...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1993-03-01 00:00:00
abstract::Cesarean delivery as a result of maternal request is increasingly popular, leading to important ethical questions. One of the challenging issues is balancing respect for the autonomy of a pregnant woman with concerns of beneficence and nonmaleficence for her and the fetus. The perceived benefit of cesarean section is ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2008.03.011
更新日期:2008-06-01 00:00:00
abstract::Although it has been customary to treat neonatal jaundice at lower serum bilirubin levels in low-birth weight infants than in term infants, the threshold bilirubin levels and long-term benefits for early treatment of preterm infants have not been validated. This article summarizes and evaluates existing evidence and s...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/s0095-5108(05)70012-9
更新日期:2000-03-01 00:00:00
abstract::Our experience in the management of 138 infants with various causes of intestinal obstruction has provided us with important principles of diagnosis and treatments that we adhere to in the course of our practice. 1. The overall mortality of neonates suffering from intestinal obstruction should be fewer than 5 per cent...
journal_title:Clinics in perinatology
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract::Discussed in this article are the effects of pregnancy-induced hypertension on the renin-angiotensin-aldosterone system; the possible role of prostanoids, deoxycorticosterone, and deoxycorticosterone sulfate in blood pressure control; and the effect of pregnancy-induced hypertension upon the endocrinology of the mater...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1983-10-01 00:00:00
abstract::This chapter describes the utility of event-related potential recordings in the assessment of auditory and visual system integrity in the newborn infant. A battery of electrophysiologic tests is described that permits the evaluation of sequential levels of processing within these sensory system. ...
journal_title:Clinics in perinatology
pub_type: 杂志文章
doi:
更新日期:1985-02-01 00:00:00
abstract::Multiple pregnancies represent a state of magnified nutritional requirements, resulting in a greater nutrient drain on maternal resources and an accelerated depletion of nutritional reserves. Maternal weight gain to 20 weeks and between 20 and 28 weeks has the greatest effect on birthweight in twin and triplet pregnan...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2005.02.005
更新日期:2005-06-01 00:00:00
abstract::Beta-sympathomimetic agents are used extensively in obstetrics to inhibit premature labor. Knowledge of the pharmacology, mode of action on smooth muscle, and cardiovascular and metabolic side effects of these agents is essential for the obstetrician and perinatologist. This review article draws extensively on recent ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1987-12-01 00:00:00
abstract::New knowledge has accumulated in recent years making it prudent to ask questions regarding current oxygenation policies and guidelines. Because new-born resuscitation affects so many individuals, and because resuscitation procedures may have dramatic consequences on infant and child health, intensified discussion and ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2004.04.021
更新日期:2004-09-01 00:00:00
abstract::The placenta not only "records" and reflects the intrauterine environment, it also provides valuable information on the cause and timing of many adverse events and conditions. The placenta may be useful in several ways. It may be the cause of injury due to an inherent abnormality, it may "malfunction" because of disea...
journal_title:Clinics in perinatology
pub_type: 杂志文章
doi:10.1016/j.clp.2007.03.013
更新日期:2007-09-01 00:00:00
abstract::Intraventricular hemorrhage (IVH) occurs in 20% to 25% of very low birthweight preterm neonates and may be associated with significant sequelae. Infants who have IVH are at risk for posthemorrhagic hydrocephalus and periventricular leukomalacia; as many as 75% of those who have parenchymal involvement of hemorrhage su...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2008.07.014
更新日期:2008-12-01 00:00:00
abstract::There is now clear evidence that dietary supplementation of omega-3 fatty acid is essential for normal eye and brain development. Corn oil-based diets induce omega-3 deficiency in preterm infants, affecting retinal responses to light, cortical visual evoked potentials, and behavioral measures of visual acuity. Preterm...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1995-03-01 00:00:00
abstract::The currently available interventional cardiac procedures in neonates and infants are at various stages of development. We currently dilate neonates and infants with critical valvular pulmonary and aortic stenosis and postoperative aortic obstruction. We do not routinely dilate native coarctation of the aorta because ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:
更新日期:1988-09-01 00:00:00
abstract::The incidence of neonatal abstinence syndrome owing to prenatal opioid exposure has grown rapidly in recent decades and it disproportionately affects rural, non-white, and public insurance-dependent populations. Treatment consists of pharmacologic and nonpharmacologic interventions with wide variability in approaches ...
journal_title:Clinics in perinatology
pub_type: 杂志文章,评审
doi:10.1016/j.clp.2019.08.012
更新日期:2019-12-01 00:00:00