Abstract:
:The aim of this study was to reduce barriers that prevent implementation of evidence-based recommendations about single-fraction palliative radiotherapy (PRT) and to demonstrate that single-fraction PRT yields similar outcomes as long-course treatment (≥10 fractions) in patients with bone metastases from breast cancer. This retrospective study (2007-2014) included 118 Norwegian female patients. All patients received guideline-conform systemic therapy including bone-targeting agents. Median survival was 12.7 months. Long-course PRT was prescribed in 60% of patients, while 21% had PRT with a single fraction of 8 Gy to at least one target. Reirradiation rate was not significantly higher after 8 Gy (9%, compared to 5% after long-course PRT and 6% after 4 Gy x5). Patients with favorable baseline characteristics such as younger age and good performance status (PS) were significantly more likely to receive long-course PRT. Biological subtype and comorbidity did not correlate with fractionation. Prognosis was influenced by biological subtype, extra-skeletal disease extent, severe anemia and abnormal CRP. The limited need for reirradiation after single fraction PRT might encourage physicians to prescribe this convenient regimen, which would improve resource utilization. Even patients with PS3 had a median survival of 3 months, which indicates that they could experience worthwhile clinical benefit.
journal_name
Int J Circumpolar Healthjournal_title
International journal of circumpolar healthauthors
Nieder C,Dalhaug A,Haukland E,Mannsåker B,Pawinski Adoi
10.1080/22423982.2016.1270080subject
Has Abstractpub_date
2017-01-01 00:00:00pages
1270080issue
1eissn
1239-9736issn
2242-3982journal_volume
76pub_type
杂志文章abstract:BACKGROUND:Community-acquired methicillin-resistant Staphylococcus aureus and methicillin-sensitive S. aureus infections are common to south-western Alaska and have been associated with traditional steambaths. More than a decade ago, recommendations were made to affected communities that included preventive skin care, ...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v75.30603
更新日期:2016-02-23 00:00:00
abstract:OBJECTIVES:Experiences in one's family of origin, especially the relationship to one's parents, supposedly form the basis of relationships in adulthood. The connection between traumatic childhood events and later life has been studied intensively, whereas average childhood growth experiences have been given less attent...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v70i2.17805
更新日期:2011-04-01 00:00:00
abstract::We report further details of the Eurowinter survey of cold related mortalities and protective measures against cold in seven regions of Europe, and review these with other evidence on the relationship of winter mortality to climate. Data for the oldest subject group studied, aged 65-74, showed that in this vulnerable ...
journal_title:International journal of circumpolar health
pub_type: 杂志文章,多中心研究
doi:
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVES:To analyze the prevalence of poor oral health and selected determinants in First Nations (FN) and Caucasian samples in Manitoba, Canada. STUDY DESIGN:Cross-sectional survey, nested in a cohort study. METHODS:FN and Caucasian participants completed a questionnaire on socio-demographic variables, oral health...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v71i0.17394
更新日期:2012-03-19 00:00:00
abstract:OBJECTIVES:The study aimed to estimate the prevalence of diabetes and impaired glucose intolerance (IGT) among Inuit migrants living in Denmark, and to compare with findings from Greenland. Further, we analyzed determinants for diabetes and impaired glucose metabolism. STUDY DESIGN:Cross-sectional, population-based ep...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v64i4.18013
更新日期:2005-09-01 00:00:00
abstract::In the first part of the study the prevalence and incidence of diagnosed Type 2 diabetes among adult rural populations of southern, central and northern areas of the Krasnoyarsk region of Siberia is compared. The six-year mean incidence of diabetes in the southern area was 0.86 per 1000 (95% CI: 0.66-1.06), in the cen...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract::The reasons for the rapidly increasing prevalence of diabetes (NIDDM) among Alaskan Eskimos are only partly understood. This study examines the association of fatty acid metabolism in 68 Alaskan Eskimos with NIDDM or impaired glucose tolerance (IGT) and 386 with normal glucose tolerance > 24 years old. The prevalence ...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVES:To trace the historical development of the Rankin Inlet Birthing Centre since its inception in 1993 in the context of plans to make it the nucleus of a system of community birthing centres throughout Nunavut. STUDY DESIGN:This is an analytical historical study using a combination of oral history interviews,...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v70i2.17803
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:Cochlear implant (CI) treatment was introduced to the world in the 1980s and has become a routine treatment for congenital or acquired severe-to-profound hearing loss. CI treatment requires access to a highly skilled team of ear, nose and throat specialists, audiologists and speech-language pathologists for e...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v72i0.20974
更新日期:2013-08-05 00:00:00
abstract::Seven-field stereo retinal photography is both 100% sensitive and specific for diagnosing diabetic retinopathy and is the standard for evaluating the severity of retinopathy both for clinical and epidemiological studies. It is also very useful for follow-up of diabetics and eventual treatment of complicated cases with...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Emerging infections have in recent years caused enormous health problems. About 70% of these infections are zoonotic e.g. arise from natural foci in the environment. As climate change impacts ecosystems there is an ongoing transition of infectious diseases in humans. With the fastest changes of the climate occurring i...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.1080/22423982.2019.1601991
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:To evaluate a community-based, not-for-profit medical group's effectiveness with diabetic management while using an electronic medical record and financial incentives. DESIGN:Descriptive retrospective study over 2 years with published reference standards. METHODS:There were 5,316 diabetic patients in the me...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v64i1.17951
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:The medical internship as a way of exposing young doctors to training in a rural context is regarded as a useful tool to recruit and retain doctors in rural areas. Norwegian health authorities tested an arrangement of early sign-up for medical internships in the Finnmark County in Norway. OBJECTIVE:To repor...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.1080/22423982.2017.1314415
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to predict the prevalence of type 2 diabetes and the associated burden to the health care system in Greenland posed by diabetic complications by 2014. The predictions were based on changes in demographic variables and obesity. STUDY DESIGN:Projection model based on two cross-...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v65i3.18106
更新日期:2006-06-01 00:00:00
abstract::Arctic peoples are spread over eight countries and comprise 3.74 million residents, of whom 9% are indigenous. The Arctic countries include Canada, Finland, Greenland (Denmark), Iceland, Norway, Russia, Sweden and the United States. Although Arctic peoples are very diverse, there are a variety of environmental and hea...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v65i1.17889
更新日期:2006-02-01 00:00:00
abstract::Our research in high latitudes has allowed the identification of a special class of deadaptive disorders, northern cardiometeopathies, which integrates cardiovascular functional violations connected to biologically significant modifications of meteorological, geomagnetic, electrical, gravitational, rhythmological and ...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract::This study deals with the adaptation of the sympathoadrenal responses to an acute cold water immersion in ordinary winter swimmers. Hormonal responses were determined at the beginning of the winter swimming period in the autumn and after regular swimming for one and three months. Water temperature in the river was 10 ...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVES:The first aim was to study how oral health care delivery was organized in member countries and to determine whether there were differences across the Barents region. The second aim was to assess the performance of the care provision systems. The Barents region is one of the largest hinterlands in northern Eu...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v69i5.17693
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Despite a growing number of studies and reports indicating a very high and increasing prevalence of trauma exposure in Greenlandic adolescents, the knowledge on this subject is still very limited. The purpose of the present study was twofold: To estimate the lifetime prevalence of potentially traumatic event...
journal_title:International journal of circumpolar health
pub_type: 杂志文章,多中心研究
doi:10.3402/ijch.v71i0.18378
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Alaska Native people are disproportionately impacted by tobacco-related diseases in comparison to non-Native Alaskans. DESIGN:We used Alaska's Behavioral Risk Factor Surveillance System (BRFSS) to describe tobacco use among more than 4,100 Alaska Native adults, stratified by geographic region and demographi...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v72i0.21208
更新日期:2013-08-05 00:00:00
abstract:BACKGROUND:Arctic residents can be exposed to a wide range of contaminants through consumption of traditional (country) foods (i.e. food from wild animals and plants that are hunted, caught or collected locally in the Arctic). Yet these foods provide excellent nutrition, promote social cohesion, meet some spiritual nee...
journal_title:International journal of circumpolar health
pub_type: 杂志文章,评审
doi:10.3402/ijch.v75.33822
更新日期:2016-12-13 00:00:00
abstract:BACKGROUND:The US commercial fishing industry is hazardous, as measured by mortality data. However, research on non-fatal injuries is limited. Non-fatal injuries constitute the majority of occupational injuries and can result in workers' lowered productivity and wages, lost quality of life, and disability. In the Unite...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v75.30070
更新日期:2016-01-14 00:00:00
abstract:OBJECTIVES:To evaluate NicAlert immunoassay test strips and liquid chromatography atmospheric-pressure ionization tandem mass spectrometry (LC/MS/MS) for the measurement of saliva cotinine levels in pregnant Alaska Native women. STUDY DESIGN:Cross-sectional study. METHODS:Pregnant women completed a questionnaire abou...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:A population-based birth registry has been set up for the Arctic town of Moncegorsk in north-western Russia. This investigation describes the health status of the delivering population, including pregnancy history and the prevalence of obesity, infections, smoking and alcohol abuse during the pregnancy perio...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v63i1.17647
更新日期:2004-03-01 00:00:00
abstract::The most important risk factors and findings of acute accidental hypothermia and concomitant local frostbites are reviewed. Both external and internal risk factors are usually present when exposure to cold is leading to death. The external factors are alcohol and psychic drugs, too light a clothing for the circumstanc...
journal_title:International journal of circumpolar health
pub_type: 杂志文章,评审
doi:
更新日期:2000-04-01 00:00:00
abstract::Ethical appraisal of medical protocols for research is now well accepted, and needed when research may carry side effects and risks that may be difficult to understand for the people invited to take part in research. We argue that time has come for Greenland to establish a formal medical research ethics committee with...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v63i0.17878
更新日期:2004-01-01 00:00:00
abstract::People with Sami and Norwegian background are frequent users of traditional folk medicine (TM). Traditional healing, such as religious prayers of healing (reading) and the laying on of hands, are examples of commonly used modalities. The global aim of this study is to examine whether health personnel's knowledge, atti...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.1080/22423982.2017.1398010
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Rickets was first described in the 17th century and vitamin D deficiency was recognized as the underlying cause in the early 1900s. Despite this long history, vitamin D deficiency remains a significant health concern. Currently, vitamin D supplementation is recommended in Canada for breast fed infants. There...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v72i0.20244
更新日期:2013-04-16 00:00:00
abstract:AIM:The aim of this study was to analyse how changes in housework over the course of adulthood are related to somatic health in Swedish men and women. METHODS:Data were drawn from 2 waves of the Northern Swedish Cohort Study, response rate 94.3%, N=1,001. A subsample of cohabiting individuals was selected (n=328 women...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v75.31781
更新日期:2016-06-30 00:00:00
abstract:OBJECTIVES:To describe the levels of obesity, adiposity measures, physical activity and fitness in Cree children aged 9-12 years. STUDY DESIGN:Cross-sectional survey. METHODS:The study took place in northern Quebec, Canada. Height, body mass, waist circumference and five skinfold thicknesses were measured. Physical a...
journal_title:International journal of circumpolar health
pub_type: 杂志文章
doi:10.3402/ijch.v65i4.18124
更新日期:2006-09-01 00:00:00