Fluoroquinolone and Third-Generation-Cephalosporin Resistance among Hospitalized Patients with Urinary Tract Infections Due to Escherichia coli: Do Rates Vary by Hospital Characteristics and Geographic Region?

Abstract:

:This analysis of nearly 10,000 hospital-associated urinary tract infection (UTI) episodes due to Escherichia coli showed that fluoroquinolone and third-generation-cephalosporin resistance rates were 34.5% and 8.6%, respectively; the rate of concurrent resistance to both agents was 7.3%. Fluoroquinolone resistance rates exceeded 25% regardless of geographic location or hospital characteristics. The findings suggest that fluoroquinolones should be reserved and third-generation cephalosporins be used with caution as empirical agents for hospitalized patients with UTIs due to E. coli.

authors

Bidell MR,Palchak M,Mohr J,Lodise TP

doi

10.1128/AAC.02505-15

subject

Has Abstract

pub_date

2016-04-22 00:00:00

pages

3170-3

issue

5

eissn

0066-4804

issn

1098-6596

pii

AAC.02505-15

journal_volume

60

pub_type

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