Abstract:
:Accounting for patients with multiple health conditions is a complex task that requires analysing potential interactions among recommendations meant to address each condition. Although some approaches have been proposed to address this issue, important features still require more investigation, such as (re)usability and scalability. To this end, this paper presents an approach that relies on reusable rules for detecting interactions among recommendations coming from various guidelines. It extends a previously proposed knowledge representation model (TMR) to enhance the detection of interactions and it provides a systematic analysis of relevant interactions in the context of multimorbidity. The approach is evaluated in a case study on rehabilitation of breast cancer patients, developed in collaboration with experts. The results are considered promising to support the experts in this task.
journal_name
Artif Intell Medjournal_title
Artificial intelligence in medicineauthors
Zamborlini V,da Silveira M,Pruski C,Ten Teije A,Geleijn E,van der Leeden M,Stuiver M,van Harmelen Fdoi
10.1016/j.artmed.2017.03.012subject
Has Abstractpub_date
2017-09-01 00:00:00pages
78-93eissn
0933-3657issn
1873-2860pii
S0933-3657(17)30150-1journal_volume
81pub_type
杂志文章abstract:OBJECTIVE:We explore the link between dataset complexity, determining how difficult a dataset is for classification, and classification performance defined by low-variance and low-biased bolstered resubstitution error made by k-nearest neighbor classifiers. METHODS AND MATERIAL:Gene expression based cancer classificat...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2008.08.004
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:In this paper, we propose a novel algorithm to extract the active intervals of intracardiac electrograms during atrial fibrillation. METHODS:First, we show that the characteristics of the signal waveform at its inflection points are prominent features that are implicitly used by human annotators for distingu...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2018.02.003
更新日期:2018-04-01 00:00:00
abstract::Early recognition of heart disease plays a vital role in saving lives. Heart murmurs are one of the common heart problems. In this study, Artificial Neural Network (ANN) is trained with Modified Neighbor Annealing (MNA) to classify heart cycles into normal and murmur classes. Heart cycles are separated from heart soun...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2017.05.005
更新日期:2017-05-01 00:00:00
abstract::Within the framework of the OPTIVIP project, an optic nerve based visual prosthesis is developed in order to restore partial vision to the blind. One of the main challenges is to understand, decode and model the physiological process linking the stimulating parameters to the visual sensations produced in the visual fi...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2004.02.004
更新日期:2004-11-01 00:00:00
abstract::If our goal in Artificial Intelligence in Medicine (AIM) is to engineer systems health-care providers will both use and, in the process, improve their performance, we must concentrate on the development of causal theories of knowledge and problem solving. One broad direction in pursuing this goal is understanding the ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章,评审
doi:10.1016/0933-3657(93)90013-s
更新日期:1993-04-01 00:00:00
abstract:OBJECTIVE:This paper proposes a novel method for the extraction and classification of individual motor unit action potentials (MUAPs) from intramuscular electromyographic signals. METHODOLOGY:The proposed method automatically detects the number of template MUAP clusters and classifies them into normal, neuropathic or ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2005.09.002
更新日期:2006-05-01 00:00:00
abstract::Hospital laboratories perform examination tests upon patients, in order to assist medical diagnosis or therapy progress. Planning and scheduling patient requests for examination tests is a complicated problem because it concerns both minimization of patient stay in hospital and maximization of laboratory resources uti...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(00)00061-0
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:A major focus in computational system biology research is defining organizing principles that govern complex biological network formation and evolution. The task is considered a major challenge because network behavior and function prediction requires the identification of functionally and statistically impor...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2007.07.006
更新日期:2007-10-01 00:00:00
abstract::Medical language is highly compositional and makes extensive use of common roots, especially Latino-Greek roots. Besides words devoted to common sense, medical language presents some typical characteristics, especially on morphological and semantic aspects of word formation. Morphological decomposition and identificat...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(98)00023-2
更新日期:1998-09-01 00:00:00
abstract:OBJECTIVE:Two major problems related the unsupervised analysis of gene expression data are represented by the accuracy and reliability of the discovered clusters, and by the biological fact that the boundaries between classes of patients or classes of functionally related genes are sometimes not clearly defined. The ma...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2008.07.014
更新日期:2009-02-01 00:00:00
abstract::Medical diagnosis and therapy planning at modern intensive care units (ICUs) have been refined by the technical improvement of their equipment. However, the bulk of continuous data arising from complex monitoring systems in combination with discontinuously assessed numerical and qualitative data creates a rising infor...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(96)00355-7
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:After several years of treatment, patients with Parkinson's disease (PD) tend to have, as a side effect of the medication, dyskinesias. Close monitoring may benefit patients by enabling doctors to tailor a personalised medication regimen. Moreover, dyskinesia monitoring can help neurologists make more inform...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2016.01.001
更新日期:2016-02-01 00:00:00
abstract::Traditional Chinese medicine has developed over more than 4000 years. A tremendous amount of medical knowledge has been accumulated, among which herbal drugs and formulae are an important portion. This paper presents an ontology for traditional Chinese drugs and formulae, and an ontology-based system for extracting kn...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2004.01.015
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:Arden Syntax is a standard for representing and sharing medical knowledge in form of independent modules and looks back on a history of 25 years. Its traditional field of application is the monitoring of clinical events such as generating an alert in case of occurrence of a critical laboratory result. Arden S...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2015.09.003
更新日期:2018-11-01 00:00:00
abstract::Case-based approaches predict the behaviour of dynamic systems by analysing a given experimental setting in the context of others. To select similar cases and to control adaptation of cases, they employ general knowledge. If that is neither available nor inductively derivable, the knowledge implicit in cases can be ut...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(98)00057-8
更新日期:1999-03-01 00:00:00
abstract::We introduce a novel approach to couple temporal similarity with spatial neighborhood information. This is achieved by concatenating the K nearest, spatially contiguous neighbors of a pixel time-course (TC) of T time-instances. This produces a new TC of (K+1)T time instances. Depending on how "nearest" is defined, we ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(02)00005-2
更新日期:2002-05-01 00:00:00
abstract::This work presents a hybrid expert system (HES) intended to minimise some complex problems pervasive to knowledge engineering such as: the knowledge elicitation process, known as the bottleneck of expert systems; the choice of a model for knowledge representation to codify human reasoning; the number of neurons in the...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(00)00090-7
更新日期:2001-01-01 00:00:00
abstract::As part of a plan to promote semi-automatic knowledge acquisition for the medical consultant system CADIAG-II/RHEUMA, this study sought to explore and cope with the variability of results that may be anticipated when performing knowledge acquisition with patient data from different patient settings. Patient data were ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(02)00025-8
更新日期:2002-07-01 00:00:00
abstract::Melanoma is the most dangerous skin cancer and early diagnosis is the key factor in its successful treatment. Well-trained dermatologists reach a diagnosis via visual inspection, and reach sensitivity and specificity levels of about 80%. Several computerised diagnostic systems were reported in the literature using dif...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/s0933-3657(02)00087-8
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:Brain-computer interfaces (BCIs) are no longer only used by healthy participants under controlled conditions in laboratory environments, but also by patients and end-users, controlling applications in their homes or clinics, without the BCI experts around. But are the technology and the field mature enough f...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2013.08.004
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:We present the implementation and application of a case-based reasoning (CBR) system for breast cancer related diagnoses. By retrieving similar cases in a breast cancer decision support system, oncologists can obtain powerful information or knowledge, complementing their own experiential knowledge, in their m...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2017.02.003
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:Coronary artery disease has been described as one of the curses of the western world, as it is one of its most important causes of mortality. Therefore, clinicians seek to improve diagnostic procedures, especially those that allow them to reach reliable early diagnoses. In the clinical setting, coronary arter...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2011.04.009
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:Progressive loss of the field of vision is characteristic of a number of eye diseases such as glaucoma which is a leading cause of irreversible blindness in the world. Recently, there has been an explosion in the amount of data being stored on patients who suffer from visual deterioration including field test...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2004.07.004
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVES:A well-developed appointment system can help increase the utilization of medical facilities in an outpatient department. This paper outlines the development of an appointment system that can make an outpatient department work more efficiently and improve patient satisfaction level. METHODS:A Markov decision...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2014.12.002
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:The objective of this work is to investigate a possibility of creating a computer-aided decision support system for an automated analysis of vocal cord images aiming to categorize diseases of vocal cords. METHODOLOGY:The problem is treated as a pattern recognition task. To obtain a concise and informative re...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2004.11.001
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:The objective of this study is to devise a modelling strategy for attaining in-silico models replicating human physiology and, in particular, the activity of the autonomic nervous system. METHOD:Discrete Multiphysics (a multiphysics modelling technique) and Reinforcement Learning (a Machine Learning algorit...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2019.06.005
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:The Arden Syntax is a knowledge-encoding standard, started in 1989, and now in its 10th revision, maintained by the health level seven (HL7) organization. It has constructs borrowed from several language concepts that were available at that time (mainly the HELP hospital information system and the Regenstrie...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2015.11.003
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:The aim of this paper is to provide an improved method for solving the so-called dynamic patient admission scheduling (DPAS) problem. This is a complex scheduling problem that involves assigning a set of patients to hospital beds over a given time horizon in such a way that several quality measures reflecting...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2016.10.002
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:The objective of the present work was to develop and compare methods for automatic detection of bilateral sleep spindles. METHODS AND MATERIALS:All-night sleep electroencephalographic (EEG) recordings of 12 healthy subjects with a median age of 40 years were studied. The data contained 6043 visually scored b...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2007.04.003
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:One of the major topics towards robot consciousness is to give a robot the capabilities of self-consciousness. We propose that robot self-consciousness is based on higher order perception of the robot, in the sense that first-order robot perception is the immediate perception of the outer world, while higher ...
journal_title:Artificial intelligence in medicine
pub_type: 杂志文章
doi:10.1016/j.artmed.2008.07.003
更新日期:2008-10-01 00:00:00